Clinical Trials at Johns Hopkins Hospital

As of June 2026, 138 paid clinical trials are recruiting at Johns Hopkins Hospital, located at JOHNS HOPKINS DEPARTMENT OF SURGERY, 600 N WOLFE ST TOWER 110, BALTIMORE, MD 21287-0001, phone (410) 955-5020 in Baltimore, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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138 clinical trials at Johns Hopkins Hospital

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320-detector Computed Tomography to Assess Myocardial Extracellular Volume Fraction in Patients With Atrial Fibrillation Before AF Ablation.

for Atrial Fibrillation

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+

Code: NCT06308094·Recruiting

Apply to this trial

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

for Metastatic Sarcoma

2 locations incl. Washington D.C.

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: Up to 39

Code: NCT06796543·Recruiting

Apply to this trial

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

55 locations incl. Birmingham

Sponsor: Celgene

Sex: Male·Age: 18+

Code: NCT06764485·Phase 3·Recruiting

Apply to this trial

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

for Psoriatic Arthritis

Drug: Zasocitinib

21 locations incl. Mesa

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06671496·Phase 3·Recruiting

Apply to this trial

Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

for Barrett Esophagus

5 locations incl. Aurora

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06687603·Recruiting

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A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

for Neurofibromatosis Type 1

14 locations incl. Birmingham

Sponsor: Healx Limited

Sex: All·Age: 12+

Code: NCT06541847·Phase 2·Recruiting

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A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

for mCRPC (Metastatic Castration-resistant Prostate Cancer)

18 locations incl. Fountain Valley

Sponsor: Pathos AI, Inc.

Sex: Male·Age: 18+

Code: NCT06785636·Phase 1, Phase 2·Recruiting

Apply to this trial

Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)

for Endometriosis

3 locations incl. Athens

Sponsor: Johns Hopkins University

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06847685·Recruiting

Apply to this trial

Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma

for Vestibular Schwannoma

4 locations incl. Baltimore

Sponsor: Akouos, Inc.

Sex: All·Age: 18+

Code: NCT06517888·Phase 1, Phase 2·Recruiting

Apply to this trial

Yoga for Back Pain in Adolescent Scoliosis

for Scoliosis Idiopathic Adolescent Treatment

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 10 - 20

Code: NCT06242821·Recruiting

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A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.

for Candidemia

23 locations incl. Birmingham

Sponsor: Basilea Pharmaceutica

Sex: All·Age: 18+

Code: NCT05421858·Phase 3·Recruiting

Apply to this trial

Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure

for Heart Failure With Reduced Ejection Fraction

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 90

Code: NCT06299436·Recruiting

Apply to this trial

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

for Leukemia

53 locations incl. Goodyear

Sponsor: Daiichi Sankyo

Sex: All·Age: 18 - 70

Code: NCT06578247·Phase 3·Recruiting

Apply to this trial

Brain Volume and Cardiac Function in Heart Failure

for Heart Failure

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+

Code: NCT06623344·Recruiting

Apply to this trial

Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

for Breast Reconstruction

22 locations incl. Los Angeles

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06575192·Phase 3·Recruiting

Apply to this trial

Adult Trauma Centers RE-AIM at Gun Safety

for Firearm Injury

3 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06302452·Enrolling By Invitation

Improving Cardiovascular Health Risks in Adults With Epilepsy on a Modified Atkins Diet

for Epilepsy

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06369571·Phase 1, Phase 2·Enrolling By Invitation

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma

for Monoclonal Gammopathy of Undetermined Significance (MGUS)

Drug: Linvoseltamab

7 locations incl. Baltimore

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06140524·Phase 2·Recruiting

Apply to this trial

Study to Evaluate the Diagnostic Performance of of MAGENTIQ-COLO During Colonoscopy.

for Screening Colonoscopy

2 locations incl. Baltimore

Sponsor: Magentiq Eye LTD

Sex: All·Age: 45 - 80·Accepts healthy volunteers

Code: NCT06568523·Not Yet Recruiting

A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

Drug: riliprubart

29 locations incl. Homewood

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06290141·Phase 3·Recruiting

Apply to this trial

Investigating Dyadic Expectations About ARF Survivorship (IDEAS)

for Acute Respiratory Failure

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06401239·Recruiting

Apply to this trial

A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Drug: riliprubart

27 locations incl. Homewood

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06290128·Phase 3·Recruiting

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A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis

for Acute Pancreatitis

11 locations incl. Little Rock

Sponsor: Panafina, Inc.

Sex: All·Age: 18 - 85

Code: NCT06080789·Phase 2·Recruiting

Apply to this trial

Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma

for Chordoma of Spine

2 locations incl. Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT06463262·Recruiting

Apply to this trial

Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy

for Total Thyroidectomy

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06383091·Recruiting

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Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention

for Respiratory Failure

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06341972·Recruiting

Apply to this trial

A Study of Pitolisant in Patients With Prader-Willi Syndrome

for Prader-Willi Syndrome

21 locations incl. Los Angeles

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 6+

Code: NCT06366464·Phase 3·Recruiting

Apply to this trial

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

for Clostridium Difficile

84 locations incl. Huntsville

Sponsor: Vedanta Biosciences, Inc.

Sex: All·Age: 12+

Code: NCT06237452·Phase 3·Recruiting

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A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast

for Idiopathic Pulmonary Fibrosis

Drug: Nerandomilast

58 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06238622·Phase 3·Recruiting

Apply to this trial

Safety of Erythropoietin and Melatonin for Very Preterm Infants With Intraventricular Hemorrhage

for Intraventricular Hemorrhage of Prematurity

2 locations incl. St. Petersburg

Sponsor: Johns Hopkins University

Sex: All·Age: 12 Hours - 2 Months

Code: NCT05617833·Phase 1·Recruiting

Apply to this trial

Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

for Primary Progressive Aphasia

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 50 - 90·Accepts healthy volunteers

Code: NCT05386394·Phase 2·Recruiting

Apply to this trial

Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).

for NF1

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06159166·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

for Hemolytic Disease of the Fetus and Newborn

Drug: Nipocalimab

18 locations incl. La Jolla

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18 - 45

Code: NCT05912517·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

Drug: Ruxolitinib

13 locations incl. Duarte

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06034002·Phase 1·Recruiting

Apply to this trial

POEM-F for Achalasia International Study

for Achalasia

1 location in Baltimore

Sponsor: Chinese University of Hong Kong

Sex: All·Age: 18 - 65

Code: NCT06042127·Recruiting

Apply to this trial

Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study)

for Fibroid

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 18 - 55

Code: NCT06135870·Recruiting

Apply to this trial

Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy

for Bladder Cancer

2 locations incl. Washington D.C.

Sponsor: Johns Hopkins University

Sex: Male·Age: 18+

Code: NCT05792722·Recruiting

Apply to this trial

A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction

for Lung Transplant Rejection

32 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06082037·Phase 3·Recruiting

Apply to this trial

The Role of IL5 in Epithelial Cell Integrity

for Chronic Rhinosinusitis With Nasal Polyps

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 100

Code: NCT05895929·EARLY_Phase 1·Recruiting

Apply to this trial

PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]

for Coronary Artery Disease

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05994014·Recruiting

Apply to this trial