Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study)

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Johns Hopkins University
Study ID
NCT06135870
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 55 Years
Healthy Volunteers
Not accepted

Study Details

The investigators are evaluating the role of senescent cells in uterine fibroids.

Key Dates

Start date
Nov 1, 2023
Status verified
Dec 2025
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
150 participants (estimated)

Arms

  • Arm: Women with fibroids undergoing elective hysterectomy or myomectomy
    Women between the age of 18-55 with fibroids undergoing elective hysterectomy or myomectomy

Primary Outcome Measure

Develop an atlas to comprehensively quantify the rate of senescent cell (SnC) types in fibroid and myometrium tissue samples [ Time Frame: 5 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Johns Hopkins HospitalBaltimoreMaryland21287
Rachel Mitchel
[email protected]

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By research site
Johns Hopkins Hospital· Baltimore, MD

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