Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)

Part of paid clinical trials in Athens, Georgia.

Sponsor
Johns Hopkins University
Study ID
NCT06847685
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 45 Years
Healthy Volunteers
Accepted

Study Details

The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy

Key Dates

Start date
Feb 1, 2025
Status verified
Mar 2026
Primary completion
Feb 1, 2029
Completion
Feb 1, 2030

Study Design

Enrollment
140 participants (estimated)

Arms

  • Arm: Women between the ages of 18 and 45 years with or without endometriosis
    50 women with endometriosis (cases) and 50 without endometriosis (controls)
  • Arm: Women between the ages of 18 and 45 years with or without endometrial cavity fluid undergoing IVF
    20 women with endometrial lumen fluid and 20 women without endometrial lumen fluid

Primary Outcome Measure

Expression levels of selected ion channels in human endometrium biopsies across the menstrual cycle. [ Time Frame: 5 years ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
University of GeorgiaAthensGeorgia30602
Xiaoqin Ye, MD, PhD
[email protected]
Xiaoqin Ye, MD, PhD (PRINCIPAL_INVESTIGATOR)
Johns Hopkins HospitalBaltimoreMaryland21287
Samya El Sayed, MD
[email protected]
James Segars, MD (PRINCIPAL_INVESTIGATOR)
Rutgers UniversityPiscatawayNew Jersey08854-

Find similar trials in Athens, GA

By condition
Endometriosis
By specialty
Women's healthFertility
By research site
University of Georgia· Athens, GAJohns Hopkins Hospital· Baltimore, MDRutgers University· Piscataway, NJ

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