Paid Clinical Trials in Winston-Salem, NC

As of June 2026, 584 paid clinical trials are recruiting in Winston-Salem, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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584 clinical trials

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Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

for Acute Leukemia of Ambiguous Lineage

Drug: Venetoclax

112 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 365 Days

Code: NCT06317662·Phase 2·Recruiting

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A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for Leukemia, Myeloid, Acute

Drug: Venetoclax

50 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06852222·Phase 3·Recruiting

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

315 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting

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A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

for B Acute Lymphoblastic Leukemia

137 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 366 Days - 46

Code: NCT06124157·Phase 2·Recruiting

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Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET

for Somatostatin Receptor Positive (SSTR+)

19 locations incl. Scottsdale

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT06784752·Phase 3·Recruiting

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A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain

for Obesity

Drug: Retatrutide

25 locations incl. Chandler

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07035093·Phase 3·Recruiting

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Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

for Prostate Cancer (Adenocarcinoma)

350 locations incl. Anchorage

Sponsor: Canadian Cancer Trials Group

Sex: Male·Age: 18+

Code: NCT06592924·Phase 3·Recruiting

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A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

for Ulcerative Colitis

25 locations incl. Canoga Park

Sponsor: Spyre Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07012395·Phase 2·Recruiting

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Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC)

for Vulvovaginal Candidiasis (VVC)

10 locations incl. Jacksonville

Sponsor: Coologics, Inc

Sex: Female·Age: 22 - 49

Code: NCT06983041·Recruiting

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Automated Robotic TCD in Traumatic Brain Injury

for Brain Injuries, Traumatic

3 locations incl. Davis

Sponsor: Virginia Commonwealth University

Sex: All·Age: 18+

Code: NCT05848297·Recruiting

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Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

for Acute Myeloid Leukemia, in Relapse

3 locations incl. Charlotte

Sponsor: ARCE Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06680752·Phase 1, Phase 2·Recruiting

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Va Meh Du: A Sports-based Mental Health Promotion Intervention for Karenni Refugees

for Coping Skills

1 location in Winston-Salem

Sponsor: University of North Carolina, Greensboro

Sex: Male·Age: 8+·Accepts healthy volunteers

Code: NCT06921499·Recruiting

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Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

129 locations incl. Tucson

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06672146·Phase 2·Recruiting

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A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine

for Acute Treatment of Migraine

13 locations incl. Little Rock

Sponsor: Pfizer

Sex: All·Age: 6 - 11

Code: NCT06995729·Phase 1·Recruiting

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Development of Quantitative Muscle Imaging as a Biomarker of Disease Endpoints in Myotonic Dystrophy

for Myotonic Dystrophy

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07362875·Recruiting

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COmmunities Aligned to Reduce Concussion and Head Impact Exposure

for Concussions

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 11 - 14·Accepts healthy volunteers

Code: NCT06624202·Recruiting

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A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndromes

23 locations incl. Duarte

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06499285·Phase 3·Recruiting

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A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

16 locations incl. Scottsdale

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06747351·Phase 3·Recruiting

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Tube Size Randomized Trial During Emergency Tracheal Intubation

for Acute Respiratory Failure

7 locations incl. Birmingham

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06939361·Enrolling By Invitation

A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)

for Narcolepsy Type 2

31 locations incl. Auburn

Sponsor: Takeda

Sex: All·Age: 18 - 70

Code: NCT06952699·Phase 2·Recruiting

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Evaluating the Effect of Surgical Drain Securement on Patient Quality of Life and Postoperative Drain-related Complications

for Surgical Drain

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06916286·Recruiting

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Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

for Atherosclerotic Cardiovascular Disease (ASCVD)

Drug: Inclisiran

37 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 80

Code: NCT06813911·Phase 3·Recruiting

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A Study of HyQvia in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) in Routine Clinical Care

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

9 locations incl. Rancho Mirage

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06538064·Recruiting

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Project neuroARTEMIS

for Stimulant Use

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 59

Code: NCT06814275·Recruiting

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Preoperative Fasting vs. Not Fasting in Critically Ill Patients

for Critical Illness

19 locations incl. Palo Alto

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06751043·Recruiting

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Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

3 locations incl. Orange

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT06704269·Phase 1, Phase 2·Recruiting

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Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

for Acute Respiratory Failure

9 locations incl. Chicago

Sponsor: Brian Driver

Sex: All·Age: 18+

Code: NCT06934876·Recruiting

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Seizure Prevention in Traumatic Brain Injury With Levetiracetam and Lacosamide

for Traumatic Brain Injury

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06866691·Phase 4·Recruiting

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An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

for Progressive Pulmonary Fibrosis

23 locations incl. Birmingham

Sponsor: Avalyn Pharma Inc.

Sex: All·Age: 18+

Code: NCT06951217·Phase 2·Recruiting

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

146 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting

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A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

for Lymphoma, Large B-Cell, Diffuse

Drug: Polatuzumab Vedotin

70 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06890884·Phase 2·Recruiting

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Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

for Leukemia, Myeloid, Acute

Drug: Venetoclax

2 locations incl. Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06580106·Recruiting

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Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

for Extensive Stage Lung Small Cell Carcinoma

Drug: Atezolizumab

43 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06287775·Phase 1, Phase 2·Recruiting

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Sacroiliac (SI) Joint Transfixing and Fusion: Meaningful Long Term Outcomes With Nevro1

for Sacroiliac Joint Dysfunction

5 locations incl. Lodi

Sponsor: Nevro Corp

Sex: All·Age: 21+

Code: NCT06909292·Recruiting

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The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

for Anesthesia

9 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06802224·Phase 4·Recruiting

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A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

for Advanced Solid Tumors Cancer

11 locations incl. Los Angeles

Sponsor: Nimbus Wadjet, Inc.

Sex: All·Age: 18 - 99

Code: NCT06898450·Phase 1, Phase 2·Recruiting

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DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

for Endometrial Cancer

Drug: Rilvegostomig

60 locations incl. Tucson

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT06989112·Phase 3·Recruiting

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Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

for Non-small Cell Lung Cancer

2 locations incl. Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06567704·Recruiting

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Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

for Advanced Solid Tumor

Drug: AI-081

19 locations incl. Birmingham

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT06635785·Phase 1, Phase 2·Recruiting

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Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study

for Alcohol Use Disorder

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT06770556·Recruiting

Apply to this trial