A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain

Part of paid clinical trials in Chandler, Arizona.

Sponsor
Eli Lilly and Company
Study ID
NCT07035093
Phase
PHASE3
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Retatrutide — DRUG
    Administered SC
  • Placebo — DRUG
    Administered SC

Study Details

The main purpose of this study is to evaluate the efficacy and safety of retatrutide in relieving chronic low back pain in participants who have obesity or overweight. Participation in the study will last about 80 weeks.

Key Dates

Start date
May 29, 2025
Status verified
May 2026
Primary completion
Sep 30, 2027
Completion
Sep 30, 2027

Study Design

Enrollment
586 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Retatrutide
    Participants will receive Retatrutide subcutaneously (SC)
  • Placebo Comparator: Placebo
    Participants will receive Placebo SC

Primary Outcome Measure

Change from Baseline in Pain Intensity Per Numeric Rating Scale [ Time Frame: Baseline, up to 72 weeks ]

Central Contacts

  • Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
    1-317-615-4559
    [email protected]
  • Physicians interested in becoming principal investigators please contact
    [email protected]

Locations (25)

FacilityCityStateZIPSite coordinators
MD First Research - ChandlerChandlerArizona85286
480-508-1038
Hemant Pandey (PRINCIPAL_INVESTIGATOR)
Tucson Orthopaedic Institute - North Wyatt DriveTucsonArizona85712
520-404-0276
Nebojsa Skrepnik (PRINCIPAL_INVESTIGATOR)
Ark Clinical Research - Fountain ValleyFountain ValleyCalifornia92708
714-988-2021
Justin Yanuck (PRINCIPAL_INVESTIGATOR)
St Joseph Heritage HealthcareFullertonCalifornia92835
714-626-8610
Shirley Pang (PRINCIPAL_INVESTIGATOR)
Clinical Research InstituteLos AngelesCalifornia90048
323-879-9999
David Kudrow (PRINCIPAL_INVESTIGATOR)
Artemis Institute for Clinical ResearchSan DiegoCalifornia92123
858-278-3647
Stacey Layle (PRINCIPAL_INVESTIGATOR)
Alpine Clinical Research CenterBoulderColorado80301
303-443-7229
Paul Brownstone, MD (PRINCIPAL_INVESTIGATOR)
K2 Medical Research - Daytona BeachDaytona BeachFlorida32114
Joshua Eisenhut (PRINCIPAL_INVESTIGATOR)
Flourish Research - Miami, LLCMiamiFlorida33135
305-631-6704
Mark Kutner (PRINCIPAL_INVESTIGATOR)
IMA Clinical Research St. PetersburgSt. PetersburgFlorida33704
727-521-9137
Howard Chipman (PRINCIPAL_INVESTIGATOR)
Care Access - TampaTampaFlorida33625
813-771-5980
Shital Mehta (PRINCIPAL_INVESTIGATOR)
Charter Research - Lady LakeThe VillagesFlorida32162
Stephen Miller (PRINCIPAL_INVESTIGATOR)
Conquest ResearchWinter ParkFlorida32789
407-916-0060
Anand Patel (PRINCIPAL_INVESTIGATOR)
Cotton O'Neil Clinical Research CenterTopekaKansas66606
785-354-9591
Katherine Willingham (PRINCIPAL_INVESTIGATOR)
Care Access - Lake Charles (Bayou Pines)Lake CharlesLouisiana70601
337-602-6642
William Nabours (PRINCIPAL_INVESTIGATOR)
MedVadis Research CorporationWalthamMassachusetts02451
617-744-1310
David DiBenedetto (PRINCIPAL_INVESTIGATOR)
Great Lakes Research Group, Inc.Bay CityMichigan48706
989-895-9100
Jeffrey Potts (PRINCIPAL_INVESTIGATOR)
Clinvest Headlands LlcSpringfieldMissouri65807
417-883-7889
Ralph Duda (PRINCIPAL_INVESTIGATOR)
Center for Clinical ResearchWinston-SalemNorth Carolina27103
Leonardo Kapural (PRINCIPAL_INVESTIGATOR)
Altoona Center For Clinical ResearchDuncansvillePennsylvania16635
814-693-0300
Alan Kivitz (PRINCIPAL_INVESTIGATOR)
New Phase Research and DevelopmentKnoxvilleTennessee37909
Natalie Clarke (PRINCIPAL_INVESTIGATOR)
FutureSearch Trials of NeurologyAustinTexas78731
512-380-9925
Gregory Tempest (PRINCIPAL_INVESTIGATOR)
Mercy Family ClinicDallasTexas75208
281-944-3610
Ebere Israel Azubuike, MD (PRINCIPAL_INVESTIGATOR)
Houston Research InstituteHoustonTexas77079
281-809-3234
David Huang (PRINCIPAL_INVESTIGATOR)
Sovah Clinical Research-River DistrictDanvilleVirginia24541
James Dailey (PRINCIPAL_INVESTIGATOR)

Find similar trials in Chandler, AZ

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
MD First Research - Chandler· Chandler, AZTucson Orthopaedic Institute - North Wyatt Drive· Tucson, AZArk Clinical Research - Fountain Valley· Fountain Valley, CASt Joseph Heritage Healthcare· Fullerton, CAClinical Research Institute· Los Angeles, CAArtemis Institute for Clinical Research· San Diego, CA

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