Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.

Part of paid clinical trials in Boston, Massachusetts.

Sponsor
Columbia University
Study ID
NCT01998750
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
N/A - 80 Years
Healthy Volunteers
Not accepted

Study Details

This study aims to investigate genetic causes of early childhood obesity. The investigators will enroll children and adults with severe early onset obesity (BMI \> 99th percentile) diagnosed prior to 6 years of age. The investigators will ask questions about the health and eating behavior of the participants, and perform a brief physical examination. The investigators will collect saliva or blood to perform genetic testing from the participants and invite family members to enroll in the study.

Key Dates

Start date
Feb 28, 2014
Status verified
Oct 2025
Primary completion
Dec 31, 2026
Completion
Dec 31, 2030

Study Design

Enrollment
500 participants (estimated)

Arms

  • Arm: Early-onset severe obesity
    The study will enroll individuals with early onset severe obesity (BMI \> 99th percentile noted at an age \< 6 years of age). Individuals with a known history of early onset obesity are eligible, regardless of their current age.

Primary Outcome Measure

Identification of known or novel genetic variants in genes that underlie obesity. [ Time Frame: 1.5-2 years ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Boston Children's HospitalBostonMassachusetts02115-
Columbia University Medical CenterNew YorkNew York10032
Vidhu Thaker, MD
[email protected]
212-851-5315

Find similar trials in Boston, MA

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Boston Children's Hospital· Boston, MAColumbia University Medical Center· New York, NY

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