Paid Clinical Trials in Tennessee

Tennessee has 2,156 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,156 clinical trials

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BeSMART Secure Storage Counseling in the Inpatient Setting

for Firearm Injury

2 locations incl. Aurora

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06485141·Recruiting

Apply to this trial

DESTINY-PANTUMOUR04

for Adenocarcinoma (NOS)

17 locations incl. Birmingham

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT07124000·Recruiting

Apply to this trial

ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for Anatomic Stage I Breast Cancer AJCC v8

652 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06876714·Phase 3·Recruiting

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Positron Emission Tomography (PET) Contrast Agent Kinetics and Safety: [18F]-Fluoromannitol

for Healthy

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07110519·EARLY_Phase 1·Recruiting

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A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

for Alzheimers Disease

Drug: Trontinemab

35 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07169578·Phase 3·Recruiting

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Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype

for Chronic Obstructive Pulmonary Disease

Drug: Lunsekimig

54 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 40 - 80

Code: NCT07190222·Phase 3·Recruiting

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High vs. Standard Dose Influenza Vaccines in Lung Transplant (Repeater)

for Immunization

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07192458·Phase 2·Recruiting

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A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

for Extensive Stage Small Cell Lung Cancer

Drug: Tarlatamab

13 locations incl. Gilbert

Sponsor: Amgen

Sex: All·Age: 18 - 90

Code: NCT07037758·Phase 1·Recruiting

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A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy

for Spinal Muscular Atrophy

Drug: Apitegromab

14 locations incl. Phoenix

Sponsor: Scholar Rock, Inc.

Sex: All·Age: Up to 2

Code: NCT07047144·Phase 2·Recruiting

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A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

for Osteoarthritis

Drug: Orforglipron

26 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07153471·Phase 3·Recruiting

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5-Year Postoperative Outcomes of Patients Who Completed the CREST Study

for Open-angle Glaucoma (OAG)

10 locations incl. Newport Beach

Sponsor: Iantrek, Inc.

Sex: All·Age: All ages

Code: NCT07480343·Enrolling By Invitation

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

for HIV Infections

7 locations incl. San Francisco

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06665646·Phase 1·Recruiting

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A Study in Subjects With Neurogenic Orthostatic Hypotension

for Neurogenic Orthostatic Hypotension

5 locations incl. Scottsdale

Sponsor: CuraSen Therapeutics, Inc.

Sex: All·Age: 18 - 85

Code: NCT07089043·Phase 2·Recruiting

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A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO

for Neovascular Age-Related Macular Degeneration (NVAMD)

49 locations incl. Scottsdale

Sponsor: EyeBiotech Ltd.

Sex: All·Age: 18+

Code: NCT07205887·Phase 2·Recruiting

Apply to this trial

AMEND TS Early Feasibility Study

for Symptomatic Functional MR 3 or Greater

11 locations incl. Phoenix

Sponsor: Valcare Medical Ltd.

Sex: All·Age: 21+

Code: NCT06951672·Recruiting

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A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

22 locations incl. Sun City

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06919965·Phase 3·Recruiting

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Neoadjuvant Darolutamide Alone or in Combination With Standard Therapy for Stage II-IIIA, AR+, TNBC

for Anatomic Stage II Breast Cancer AJCC v8

1 location in Nashville

Sponsor: Vandana Abramson

Sex: All·Age: 18+

Code: NCT07016399·Phase 2·Recruiting

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Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

for Metastatic Clear Cell Renal Cell Carcinoma

Drug: Cabozantinib

40 locations incl. Gilbert

Sponsor: Arcus Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07011719·Phase 3·Recruiting

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Validation of Donor-Derived Cell-Free DNA (Dd-cfDNA) for Kidney Transplant Monitoring

for Kidney Transplant Rejection

8 locations incl. Los Angeles

Sponsor: Insight Molecular Diagnostics

Sex: All·Age: 18+

Code: NCT07060716·Recruiting

Apply to this trial

Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial

for Other

31 locations incl. Newark

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06904391·Recruiting

Apply to this trial

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial

for Childhood Cancer Survivor

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 10 - 17

Code: NCT07160621·Recruiting

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A Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

36 locations incl. Phoenix

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06973187·Phase 3·Recruiting

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High-Resolution PET-CT Imaging for Surgical Margin Visualization

for Cancer

1 location in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT06915454·Recruiting

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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity

for Obesity

4 locations incl. Doral

Sponsor: MBX Biosciences

Sex: All·Age: 18 - 65

Code: NCT07142707·Phase 1·Recruiting

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Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial

for Postoperative Nausea

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07152249·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

for Colorectal Cancer

22 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07023289·Phase 2·Recruiting

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Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

for Elevated Lp(a)

Drug: Muvalaplin

121 locations incl. Gilbert

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07157774·Phase 3·Recruiting

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A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

for Metastatic Castration-resistant Prostate Neoplasms

Drug: Pasritamig

50 locations incl. La Jolla

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT07164443·Phase 3·Recruiting

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2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients

for Alzheimer Disease

1 location in Nashville

Sponsor: MTI Biotech Inc

Sex: All·Age: 55 - 85

Code: NCT06432166·Phase 1, Phase 2·Not Yet Recruiting

Contingency Management to Reinforce Attendance to Cognitive Behavioral Treatment for Gambling Disorder

for Gambling Disorder

1 location in Johnson City

Sponsor: East Tennessee State University

Sex: All·Age: 18+

Code: NCT07016100·Not Yet Recruiting

Injection Versus Suture Repair of Laryngeal Clefts

for Laryngeal Cleft

2 locations incl. Portland

Sponsor: Oregon Health and Science University

Sex: All·Age: 12 Months - 10

Code: NCT07057258·Enrolling By Invitation

Clinical Performance Study of Microbio InfectID-BSI for Detection of Bacteria and Yeast With Patient Blood Samples

for Bloodstream Infection

5 locations incl. Indianapolis

Sponsor: Microbio Co Ltd

Sex: All·Age: All ages

Code: NCT06531031·Not Yet Recruiting

Stenting for Ischemic Strokes Secondary to Medically Refractory Intracranial Atherosclerotic Disease

for ICAD - Intracranial Atherosclerotic Disease

1 location in Memphis

Sponsor: Nitin Goyal

Sex: All·Age: 18+

Code: NCT06790147·Not Yet Recruiting

Sentence Shaping - DHH

for Hearing Loss, Bilateral

1 location in Nashville

Sponsor: Vanderbilt University

Sex: All·Age: 9 - 15

Code: NCT06860022·Recruiting

Apply to this trial

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

for Renal Cell Carcinoma

5 locations incl. Boston

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06966024·Phase 1·Recruiting

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A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

for Metastatic Gastric Adenocarcinoma

19 locations incl. Chandler

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07043400·Phase 3·Recruiting

Apply to this trial

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

for Advanced Pancreatic Carcinoma

109 locations incl. Birmingham

Sponsor: Sameek Roychowdhury

Sex: All·Age: 18+

Code: NCT06906562·Phase 2·Recruiting

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A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE) and Sjogren's Disease (SjD)

for Dry Eye Syndrome

4 locations incl. Margate

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06977724·Phase 1·Recruiting

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Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

for PIK3CA Mutation

51 locations incl. Gilbert

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06982521·Phase 3·Recruiting

Apply to this trial

Study to Evaluate Efficacy and Dose Response of Imapextide (STEADI)

for Postbariatric Hypoglycemia

4 locations incl. Aurora

Sponsor: MBX Biosciences

Sex: All·Age: 18 - 75

Code: NCT07029412·Phase 2·Recruiting

Apply to this trial