Paid Clinical Trials in Tennessee

Tennessee has 2,156 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,156 clinical trials

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Evaluating the Safety, Tolerability, and Efficacy of GRF312 5% in Participants With Dry Eye Disease (DED).

for Dry Eye Disease

10 locations incl. Glendale

Sponsor: Instituto Grifols, S.A.

Sex: All·Age: 18+

Code: NCT07264517·Phase 2·Recruiting

Apply to this trial

A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa (HS)

31 locations incl. Phoenix

Sponsor: Bluefin Biomedicine, Inc.

Sex: All·Age: 18 - 75

Code: NCT07287644·Phase 2, Phase 3·Recruiting

Apply to this trial

De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia

for Congenital Diaphragmatic Hernia

19 locations incl. Birmingham

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 Months - 1 Month

Code: NCT05213676·Phase 4·Recruiting

Apply to this trial

CCM OPEN HF Registry

for Heart Failure

28 locations incl. Mesa

Sponsor: Impulse Dynamics

Sex: All·Age: 18+

Code: NCT07112924·Recruiting

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Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work

for Dry Eye

3 locations incl. Pittsburg

Sponsor: Southern College of Optometry

Sex: All·Age: 18 - 75

Code: NCT07266948·Phase 4·Recruiting

Apply to this trial

Worldwide Assessment of Deceased Donor Kidney Utilization

for Kidney Failure

1 location in Nashville

Sponsor: Paris Translational Research Center for Organ Transplantation

Sex: All·Age: All ages

Code: NCT07341516·Enrolling By Invitation

An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye

for Dry Eye

5 locations incl. Newport Beach

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07179055·Phase 2·Recruiting

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Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

for Peripheral Arterial Disease

Drug: Orforglipron

30 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07223593·Phase 3·Recruiting

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

50 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting

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A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks

for Eosinophilic Esophagitis

41 locations incl. Little Rock

Sponsor: Phathom Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06851559·Phase 2·Recruiting

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Retinal Detachment Prevention (Laser Prophylaxis) in Stickler Syndrome (SS)

for Stickler Syndrome Type 1

5 locations incl. Birmingham

Sponsor: Helen Keller Eye Research Foundation

Sex: All·Age: All ages

Code: NCT07146516·Recruiting

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ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

for Breast Neoplasms

Drug: Pumitamig

26 locations incl. Springdale

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT07173751·Phase 3·Recruiting

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A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

for HNSCC

9 locations incl. Denver

Sponsor: Normunity AccelCo, Inc.

Sex: All·Age: 18+

Code: NCT07182149·Phase 1·Recruiting

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An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE)

for Bipolar Depression

15 locations incl. Little Rock

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18 - 75

Code: NCT07217860·Phase 3·Enrolling By Invitation

Exploring the Physiologic, Pharmacodynamic, and Clinical Responses of Skeletal Muscle in Patients With Spinal Muscular Atrophy Treated With SMN-Directed Therapies

for Spinal Muscular Atrophy

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 5 - 20

Code: NCT06532474·Recruiting

Apply to this trial

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Bevacizumab

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701656·Phase 2·Recruiting

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Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in Pediatric PNH Patients

for Paroxysmal Nocturnal Hemoglobinuria (PNH)

Drug: Iptacopan

3 locations incl. New Brunswick

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 2 - 18

Code: NCT06934967·Phase 3·Recruiting

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OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

for Cardiac Failure

7 locations incl. Los Angeles

Sponsor: Inova Health Care Services

Sex: All·Age: 18 - 99

Code: NCT06939751·Recruiting

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A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

for Colorectal Cancer

9 locations incl. New Haven

Sponsor: Criterium, Inc.

Sex: All·Age: 18+

Code: NCT06992258·Phase 2·Recruiting

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Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

for Breast Cancer

12 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18 - 99

Code: NCT07211178·Recruiting

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A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

Drug: Divarasib

50 locations incl. Anchorage

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06793215·Phase 3·Recruiting

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BoxX-NoAF Clinical Trial

for Post Operative Atrial Fibrillation

14 locations incl. Jonesboro

Sponsor: AtriCure, Inc.

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06989775·Recruiting

Apply to this trial

CAR T-cell Long-Term Follow-Up, Quality of Life and Adverse Reactions

for B-Cell Acute Lymphoblastic Leukemia (B-ALL)

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT07048535·Recruiting

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A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease

for Dry Eye Disease

32 locations incl. Phoenix

Sponsor: Bausch & Lomb Incorporated

Sex: All·Age: 18+

Code: NCT07128628·Phase 2·Recruiting

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A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

for Non-alcoholic Fatty Liver Disease

49 locations incl. Arcadia

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 75

Code: NCT07221227·Phase 3·Recruiting

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Evaluation of TL-925 for the Treatment of Seasonal Allergic Conjunctivitis

for Allergic Conjunctivitis

1 location in Smyrna

Sponsor: Telios Pharma, Inc.

Sex: All·Age: 18+

Code: NCT07220408·Phase 2·Recruiting

Apply to this trial

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

for Heart Failure - NYHA II - IV

32 locations incl. Huntsville

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07069738·Recruiting

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A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

for Ovarian Neoplasms

82 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213804·Phase 3·Recruiting

Apply to this trial

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

for Asthma

Drug: Brenipatide

17 locations incl. Tempe

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07219173·Phase 2·Recruiting

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Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy

for Ig-E Mediated Food Allergy

Drug: RPT904

17 locations incl. Little Rock

Sponsor: RAPT Therapeutics, Inc.

Sex: All·Age: 12 - 55

Code: NCT07220811·Phase 2·Recruiting

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A Clinical Trial Assessing the Safety and Effectiveness of the DurAVR® THV System

for Severe Aortic Stenosis

3 locations incl. San Francisco

Sponsor: Anteris Technologies Ltd.

Sex: All·Age: 18+

Code: NCT07194265·Recruiting

Apply to this trial

A Study of JNT-517 in Participants With Phenylketonuria (PKU)

for Phenylketonuria

10 locations incl. Los Angeles

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 18+

Code: NCT06971731·Phase 3·Recruiting

Apply to this trial

Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation

for Atrial Fibrillation (AF)

35 locations incl. Dothan

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07175428·Phase 2·Recruiting

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A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

for Neoplasms, Colorectal

3 locations incl. Detroit

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07213609·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study of S-892216-PO in Participants With Renal Impairment and Matched Controls

for Renal Impairment

4 locations incl. Orlando

Sponsor: Shionogi

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07217886·Phase 1·Recruiting

Apply to this trial

Safety and Effectiveness Evaluation of the High-intensity Focused Ultrasound Device for Lifting Lax Submental and Neck Tissue

for Skin Laxity (Submental and Neck)

5 locations incl. Los Angeles

Sponsor: CLASSYS Inc.

Sex: All·Age: 30 - 65·Accepts healthy volunteers

Code: NCT07229430·Recruiting

Apply to this trial

ResQ133A-NMIBC: Intravesical Recombinant Mycobacterium (rMBCG) in Participants With NMIBC Eligible to Receive Intravesical Tice BCG

for NMIBC

9 locations incl. Chandler

Sponsor: ImmunityBio, Inc.

Sex: All·Age: 18 - 85

Code: NCT06800963·Phase 1, Phase 2·Recruiting

Apply to this trial

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

for Metabolic Dysfunction-Associated Steatotic Liver Disease

140 locations incl. Tuscaloosa

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07165028·Phase 3·Recruiting

Apply to this trial

STrong Relationships to Improve DiabEtes Pilot

for Type 2 Diabetes

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 75

Code: NCT07210593·Enrolling By Invitation

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

for Chronic Lymphocytic Leukemia (CLL)

13 locations incl. Duarte

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07221500·Phase 2·Recruiting

Apply to this trial