Worldwide Assessment of Deceased Donor Kidney Utilization

Part of paid clinical trials in Nashville, Tennessee.

Sponsor
Paris Translational Research Center for Organ Transplantation
Study ID
NCT07341516
Status
Enrolling By Invitation

Conditions

  • Deceased Donor Kidney Transplant
  • Kidney Failure
  • Kidney Transplant

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Study Details

The persistent imbalance between kidney transplant demand and organ availability remains a major global challenge. Optimizing the utilization of kidneys from deceased donors is a critical strategy to expand the donor pool and increase access to transplantation. Previous studies have demonstrated substantial international differences in kidney acceptance and discard practices, with significant potential gains in allograft life-years through optimized utilization. However, major changes in allocation policies, donor characteristics, preservation technologies, and global events such as the COVID-19 pandemic may have altered contemporary utilization patterns. This study aims to characterize international trends in deceased donor kidney utilization, compare allograft survival across countries, and estimate potential transplantable allograft life-years gained through improved utilization practices.

Key Dates

Start date
Nov 1, 2025
Status verified
Dec 2025
Primary completion
Nov 30, 2026
Completion
Nov 30, 2026

Study Design

Enrollment
300,000 participants (estimated)

Primary Outcome Measure

Kidney allograft discard [ Time Frame: Day 0 ]

Locations (1)

FacilityCityStateZIPSite coordinators
Vanderbilt Center for Transplant Science, Vanderbilt University Medical Center, Nashville, TN, USANashvilleTennessee37232-

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Vanderbilt Center for Transplant Science, Vanderbilt University Medical Center, Nashville, TN, USA· Nashville, TN

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