Paid Clinical Trials in Tennessee

Tennessee has 2,156 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,156 clinical trials

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Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Upper Extremities

for Actinic Keratosis

20 locations incl. Phoenix

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 18 - 85

Code: NCT07144852·Phase 3·Recruiting

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A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

29 locations incl. Goodyear

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT07213674·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures

for Focal Seizures

24 locations incl. Phoenix

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 12 - 75

Code: NCT07233239·Phase 1·Recruiting

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Observational Study of VYKAT™ XR in Patients With Prader-Willi Syndrome

for Prader-Willi Syndrome

15 locations incl. Los Angeles

Sponsor: Soleno Therapeutics, Inc.

Sex: All·Age: 4+

Code: NCT07450664·Enrolling By Invitation

Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial

for Muscle Invasive Bladder Urothelial Carcinoma

143 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07061964·Phase 2·Recruiting

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Phase I Clinical Study To Evaluate Pharmacokinetic Profile, Safety, Efficacy and Immunogenicity Of Ipilimumab Biosimilar HLX13 Vs. YERVOY® (US-Sourced YERVOY®) As A First-Line Treatment For Patients With Unresectable Hepatocellular Carcinoma

for Hepatocellular Carcinoma (HCC)

Drug: Ipilimumab

11 locations incl. Glendale

Sponsor: Shanghai Henlius Biotech

Sex: All·Age: 18 - 65

Code: NCT07176650·Phase 1·Recruiting

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Planning Together: A Couple-based, Multi-level Prenatal Contraceptive Education Program for Economically Marginalized Families

for Short Interpregnancy Intervals

1 location in Knoxville

Sponsor: University of Tennessee Graduate School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07214012·Recruiting

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A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions.

for Ankle Arthrodesis or Arthroplasty

5 locations incl. Vail

Sponsor: Kuros Biosurgery AG

Sex: All·Age: 18 - 75

Code: NCT07225751·Recruiting

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Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease

for Sickle Cell Disease

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 8 - 17

Code: NCT07226219·Phase 1·Recruiting

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Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months

for Endometrial Hyperplasia

69 locations incl. Birmingham

Sponsor: Bayer

Sex: Female·Age: 18+

Code: NCT06904274·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for Parkinson's Disease

Drug: Prasinezumab

42 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 85

Code: NCT07174310·Phase 3·Recruiting

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Restoring Iron Deficiency in POTS

for POTS - Postural Orthostatic Tachycardia Syndrome

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18 - 45

Code: NCT07197905·Phase 2·Recruiting

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Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

for Macular Telangiectasia Type 2 (MacTel)

23 locations incl. La Jolla

Sponsor: Neurotech Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06971939·Phase 4·Recruiting

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Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

75 locations incl. Birmingham

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT07231419·Phase 3·Recruiting

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Evaluation of the Safety, Efficacy, and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma

for Metastatic Uveal Melanoma

3 locations incl. Scottsdale

Sponsor: Novelwise Pharmaceutical Corporation

Sex: All·Age: 18+

Code: NCT07136181·Phase 1, Phase 2·Recruiting

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Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp

for Actinic Keratosis

10 locations incl. Fremont

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 18 - 85

Code: NCT07144345·Phase 3·Recruiting

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Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)

for Autosomal Dominant Polycystic Kidney Disease (ADPKD)

26 locations incl. Alabaster

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 65

Code: NCT07161037·Phase 2·Recruiting

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A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

for Advanced or Metastatic Solid Tumors

15 locations incl. Santa Monica

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07205718·Phase 1, Phase 2·Recruiting

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Gene Therapy for HER-Positive Cancer (SENTRY-HER2)

for HER2 Expressing Solid Tumors

6 locations incl. Los Angeles

Sponsor: Vironexis Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT07192432·Phase 1, Phase 2·Recruiting

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Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

for Metastatic Colorectal Cancer (CRC)

Drug: Bevacizumab

58 locations incl. Goodyear

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT07228832·Phase 3·Recruiting

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A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

for Non Small Cell Lung Cancer

11 locations incl. San Francisco

Sponsor: Rondo Therapeutics

Sex: All·Age: 18+

Code: NCT07218003·Phase 1·Enrolling By Invitation

Discovery Diabetes

for Type 1 Diabetes

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 13 - 21

Code: NCT07116434·Recruiting

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A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

for Idiopathic Pulmonary Fibrosis

Drug: BI 765423

15 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07036523·Phase 2·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

for Ovarian Cancer

23 locations incl. La Jolla

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT07059845·Phase 2·Recruiting

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A Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS)

for Multiple Sclerosis

9 locations incl. Carlsbad

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18 - 65

Code: NCT07074886·Phase 2·Recruiting

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A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

for Bladder Cancer

10 locations incl. Los Angeles

Sponsor: EvolveImmune United, Inc

Sex: All·Age: 18+

Code: NCT07217171·Phase 1·Recruiting

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A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Psoriatic Arthritis

for Arthritis, Psoriatic

16 locations incl. Avondale

Sponsor: MoonLake Immunotherapeutics AG

Sex: All·Age: 18+

Code: NCT07223138·Phase 3·Enrolling By Invitation

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

for B-cell Acute Lymphoblastic Leukemia (B-ALL)

6 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07109219·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis (SPMS)

Drug: Remibrutinib

30 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07225504·Phase 3·Recruiting

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A Safety and Efficacy Long-Term Follow-up Study of Adult Participants Treated With Gene Modified T Cells

for Long Term Safety Following GM T Cell Therapy

1 location in Nashville

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06798298·Recruiting

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A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

for Neuroblastoma Recurrent

4 locations incl. San Francisco

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT07085338·Phase 2·Recruiting

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A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)

for Hypothalamic Obesity

6 locations incl. Aurora

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 12+

Code: NCT07156578·Phase 2·Enrolling By Invitation

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

for Ulcerative Colitis

Drug: LY4268989

41 locations incl. Scottsdale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07186101·Phase 2·Recruiting

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Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

for BRAF V600 Mutation

Drug: Dabrafenib

6 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 12 Months - 25

Code: NCT07110246·Phase 2·Recruiting

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A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

for Lymphoma

14 locations incl. Aurora

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT07015242·Phase 2·Recruiting

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A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

for Non-muscle Invasive Bladder Cancer

39 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07206225·Phase 1·Recruiting

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Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

for Neovascular Age-related Macular Degeneration

Drug: Surabgene Lomparvovec

53 locations incl. Mesa

Sponsor: AbbVie

Sex: All·Age: 50+

Code: NCT07007065·Phase 3·Recruiting

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Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

for Non-Small Cell Lung Cancer

28 locations incl. Irvine

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07100080·Phase 2, Phase 3·Recruiting

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Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

for Breast Cancer

Drug: Palazestrant

28 locations incl. Hot Springs

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07085767·Phase 3·Recruiting

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Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

for Bladder Cancer

6 locations incl. Tampa

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT07225127·Recruiting

Apply to this trial