Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work

Part of paid clinical trials in Pittsburg, Kansas.

Sponsor
Southern College of Optometry
Study ID
NCT07266948
Phase
PHASE4
Status
Recruiting
Apply to this trial

Conditions

  • Dry Eye
  • Eye Diseases
  • Eyes Dry Chronic

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Acoltremon — DRUG
    Participants will be provided with Acoltremon or TRYPTYR to determine whether or not it is an effective medication to help alleviate symptoms associated with dry eye disease

Study Details

This 1-month, 3-visit study will be conducted at the Southern College of Optometry (Memphis, TN), Kannarr Eye Care, LLC (Pittsburg, KS) and Complete Eye Care of Medina (Minneapolis, MN). Adults ≥18 years of age who have been diagnosed with DED for at least 6 months and who are currently symptomatic (Eye Dryness VAS Score ≥40) will be recruited. Subjects will have an abnormal Schirmer test of \<10 mm/5 min. Subjects will also be required to score ≤70 on the IDEEL Quality of Life (QoL) Work domain to ensure that their DED symptoms are significantly impacting their ability to do work.9 Subjects will be required to have corrected distance visual acuity of 20/32 (0.2 logMAR) or better.

Key Dates

Start date
Nov 1, 2025
Status verified
Nov 2025
Primary completion
Jan 31, 2026
Completion
Mar 1, 2026

Study Design

Enrollment
40 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: TRYPTYR
    Participants who qualify for the study will be given TRYPTYR to determine if it is able to help alleviate symptoms associated with dry eye disease;

Primary Outcome Measure

Mean change from baseline in IDEEL-QoL Work scores at 28 days. [ Time Frame: 1 month ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
Kannar Eye CarePittsburgKansas66762
Shane Kannarr, OD
[email protected]
6202351737
Complete Eye Care of MedinaMedinaMinnesota55340
Gina Wesley, OD
[email protected]
763-478-3505
The Southern College of OptometryMemphisTennessee38104
Chris Lievens, OD
[email protected]
9014815699

Find similar trials in Pittsburg, KS

By research site
Kannar Eye Care· Pittsburg, KSComplete Eye Care of Medina· Medina, MNThe Southern College of Optometry· Memphis, TN

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