Non-small cell lung cancer (NSCLC) Clinical Trials in Seattle, WA
As of June 2026, 51 paid clinical trials are recruiting for Non-small cell lung cancer (NSCLC) in Seattle, Washington. Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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51 clinical trials for Non-small cell lung cancer (NSCLC)
·Clear filters·↓ Download CSVExercise Training for the Improvement of Immune Activity and Treatment Outcomes During Immunotherapy for Non-small Cell Lung Cancer, BOOST Trial
A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4
A Study of Navlimetostat (BMS-986504) in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion (MountainTAP-9)
Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
SLV-154 Treatment of Metastatic Solid Tumors
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
First in Human Study of TUB-030 in Patients With Advanced Solid Tumors
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours
A Study of the Oral EGFR Inhibitor PLB1004 in Non-Small Cell Lung Cancer
Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer
Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer
A Study of IBI363 in Subjects with Advanced Solid Malignancies
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
A Study of KK2269 in Adult Participants With Solid Tumors
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
SX-682 With Pembrolizumab for the Treatment of Metastatic or Recurrent Stage IIIC or IV Non-Small Cell Lung Cancer
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
A Study of EP0031 in Patients With Advanced RET-altered Malignancies
Testing Tumor Tissue and Blood to Help Select Personalized Treatments for Patients With Suspected Lung Cancers
Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer
About research studies in Seattle
Seattle has approximately 1,369 recruiting research studies across a wide range of therapeutic areas. Washington hosts Fred Hutchinson Cancer Center, UW Medicine, and Seattle Children's — widely recognized for leadership in bone marrow transplantation, immunotherapy, and infectious disease research.
Top Research Study Locations in Seattle
Researchers run research studies in Seattle, WA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Washington | Amyotrophic Lateral Sclerosis, Spinal Cord Injuries, Multiple Myeloma | 203 |
| Seattle Children's Hospital | Diffuse Intrinsic Pontine Glioma, Cystic Fibrosis, High Grade Glioma | 193 |
| Fred Hutchinson Cancer Center | Breast Cancer, Colorectal Cancer, Acute Myeloid Leukemia | 141 |
| Fred Hutch/University of Washington Cancer Consortium | Acute Myeloid Leukemia, Hematopoietic and Lymphatic System Neoplasm, Mixed Phenotype Acute Leukemia | 101 |
| Swedish Medical Center-First Hill | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma | 71 |
| University of Washington Medical Center | Crohn's Disease, Cystic Fibrosis, Glioblastoma | 60 |
| Swedish Cancer Institute | Breast Cancer, Multiple Myeloma, Breast Neoplasms | 47 |
| Swedish Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 45 |
| University of Washington Medical Center - Montlake | Prostate Adenocarcinoma, Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8 | 43 |
| Swedish Medical Center-Ballard Campus | Malignant Solid Neoplasm, Breast Cancer, Chronic Lymphocytic Leukemia | 42 |
| Swedish Medical Center-Cherry Hill | Malignant Solid Neoplasm, Breast Cancer, Chronic Lymphocytic Leukemia | 42 |
| Virginia Mason Medical Center | Atrial Fibrillation, Breast Cancer, Hearing Loss, Unilateral | 39 |
| Fred Hutchinson Cancer Research Center | Chronic Lymphocytic Leukemia, Advanced Solid Tumor, Mantle Cell Lymphoma | 37 |
| VA Puget Sound Health Care System Seattle Division, Seattle, WA | Lower Extremity Amputation, Obesity, Adult Growth Hormone Deficiency | 23 |
| Harborview Medical Center | Ischemic Stroke, Spinal Cord Injuries, Abdominal Aortic Aneurysms | 21 |
| Pacific Gynecology Specialists | Metastatic Malignant Neoplasm in the Brain, Stage IIIB Lung Cancer AJCC v8, Acral Lentiginous Melanoma | 20 |
| Seattle Children's | Suicidal Ideation, Acute Kidney Injury, Cancer | 17 |
| FHCC at Northwest Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 14 |
| VA Puget Sound Health Care System | Parkinson's Disease, Amputation, Barrett's Esophagus | 14 |
| Seattle Children's Research Institute | ADA SCID, Adolescent Behavior, Brain Concussion | 11 |
| Fred Hutch Cancer Center | Colon Cancer, Colorectal Cancer, Advanced Adenocarcinoma | 10 |
| Kaiser Permanente Washington | Advanced Lung Non-Small Cell Carcinoma, Alcohol Use Disorder, Alzheimer Disease, Protection Against | 10 |
| Seattle Cancer Care Alliance | Acute Myeloid Leukemia, Breast Cancer, Chronic Myelomonocytic Leukemia | 9 |
| GSK Investigational Site | HIV Infections, Non-alcoholic Fatty Liver Disease, Gastrointestinal Neoplasms | 8 |
| University of Washington - Harborview Medical Center | Aneurysm, Intracranial, Brain Aneurysm, CPAP | 7 |
Active & Upcoming Studies in Seattle (2026)
Recruiting trials in Seattle grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (528 active studies)
- ²¹¹At-OKT10-B10 and Fludarabine Alone or in Combination With Cyclophosphamide and Low-Dose TBI Before Donor Stem Cell Transplant for the Treatment of Newly Diagnosed, Recurrent, or Refractory High-Risk Multiple Myeloma · Phase 1 · Fred Hutchinson Cancer Center
- An Educational Intervention (Lung Toolkit) for Improving Knowledge About Lung Cancer and Screening Among American Indian and Alaskan Native Cigarette Smokers, Lung PATHS Trial · Fred Hutchinson Cancer Center
Neurology & pain (71 active studies)
- Morphine or Ketamine for Analgesia · Phase 3 · Columbia University
- My MS Toolkit: An Internet-Based Depression Self-Management Program for Adults Living With Multiple Sclerosis · University of Washington
Diabetes & metabolic (57 active studies)
- Inherited and Environmental Risks Acting on Body Weight · University of Washington
- A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes · Phase 3 · Novo Nordisk A/S
Cardiovascular (52 active studies)
- Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH) · Phase 2 · Stanford University
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Pediatric (30 active studies)
- Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion · EARLY_Phase 1 · Nationwide Children's Hospital
- CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) · Phase 1, Phase 2 · COUR Pharmaceutical Development Company, Inc.
Mental health & behavior (28 active studies)
- VOCALE LBD: Online Peer Support for Caregivers of People With Lewy Body Dementia · University of Washington
- A Smartphone Application (QuitBot) for the Improvement of Smoking Cessation Among American Indians and Alaska Natives, NAITIVE Trial · Fred Hutchinson Cancer Center
HIV / STI (19 active studies)
- A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults · Seattle Institute for Biomedical and Clinical Research
Vaccines (9 active studies)
- Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals · Phase 2 · Fred Hutchinson Cancer Center
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
Eye & vision (3 active studies)
- Disulfiram for Treatment of Retinal Degeneration · Phase 1, Phase 2 · University of Washington
- A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration · Phase 1 · Astellas Institute for Regenerative Medicine
Common conditions studied in Seattle
- Acute Myeloid Leukemia (33 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Breast Cancer (26 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Colorectal Cancer (18 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Ovarian Cancer (17 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Advanced Solid Tumor (16 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Cancer (16 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Seattle
- University of Washington
- Fred Hutchinson Cancer Center
- National Cancer Institute (NCI)
- Seattle Children's Hospital
- AstraZeneca
Local regulations and guidelines
Clinical trials in Washington are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Studies in Washington must also comply with the My Health My Data Act, which adds consumer-health-data protections on top of federal HIPAA requirements.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Seattle. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Seattle
Hipa.ai aggregates every recruiting study in Seattle from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Seattle?
There are approximately 1,369 recruiting clinical trials in Seattle, Washington listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Seattle pay participants?
Most recruiting trials in Seattle compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Seattle?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Seattle?
The most common conditions under active study in Seattle include Acute Myeloid Leukemia (33), Breast Cancer (26), Colorectal Cancer (18), Ovarian Cancer (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Seattle?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Seattle on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Seattle?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Seattle?
Recruiting research sites in Seattle include University of Washington, Seattle Children's Hospital, Fred Hutchinson Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Seattle right now?
The largest active categories in Seattle are Cancer & tumors (528), Neurology & pain (71), Diabetes & metabolic (57). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.