Paid Clinical Trials in South Carolina

South Carolina has 1,276 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,276 clinical trials

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Risk Adapted De-Intensification of Radio-Chemotherapy for Oropharyngeal Squamous Cell Carcinoma

for Oropharyngeal Squamous Cell Carcinoma

3 locations incl. Gainesville

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT05268614·Phase 2·Recruiting

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Embolization of the Splenic Artery After Trauma

for High-grade Splenic Injuries

5 locations incl. Birmingham

Sponsor: Andrew J. Gunn

Sex: All·Age: 15+

Code: NCT05128955·Recruiting

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Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

for Metastatic Malignant Neoplasm in the Liver

446 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05040360·Phase 2·Recruiting

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cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

for Brain Cancer

17 locations incl. Duarte

Sponsor: Adela, Inc

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT05366881·Recruiting

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NEPTUNE Match Study

for Nephrotic Syndrome in Children

16 locations incl. Atlanta

Sponsor: University of Michigan

Sex: All·Age: 1 - 80

Code: NCT04571658·Recruiting

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

164 locations incl. Birmingham

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting

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Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

25 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05316155·Phase 1, Phase 2·Recruiting

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

219 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting

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Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease

for Proteinuric Kidney Disease

227 locations incl. Alabaster

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 10 - 65

Code: NCT05312879·Phase 2, Phase 3·Recruiting

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4D-710 in Adult Patients With Cystic Fibrosis

for Cystic Fibrosis Lung

20 locations incl. Birmingham

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 18+

Code: NCT05248230·Phase 2·Recruiting

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A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for Non Small Cell Lung Cancer

Drug: Telisotuzumab Vedotin

50 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT04928846·Phase 3·Recruiting

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Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

for Solid Tumors

17 locations incl. Duarte

Sponsor: ORIC Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05315700·Phase 1, Phase 2·Recruiting

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COAST Therapy in Advanced Solid Tumors and Prostate Cancer

for Prostate Cancer Recurrent

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05036226·Phase 1, Phase 2·Recruiting

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Screening Women With Prior HPV for Anal Neoplasia

for HPV-related Lower Genital Tract Neoplasias

3 locations incl. New York

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: Female·Age: 35+

Code: NCT05217940·Recruiting

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A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

for Leukemia, Myeloid, Acute

33 locations incl. Newport Beach

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 12+

Code: NCT04988555·Phase 1, Phase 2·Recruiting

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Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects

for Migraine

Drug: Rimegepant

54 locations incl. Fort Smith

Sponsor: Pfizer

Sex: All·Age: 6 - 17

Code: NCT05156398·Phase 3·Recruiting

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Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders

for Bipolar Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 65

Code: NCT05064319·Phase 2·Recruiting

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Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for Epiretinal Membrane

45 locations incl. Scottsdale

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05145491·Recruiting

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Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

for Mitral Valve Regurgitation

24 locations incl. Los Angeles

Sponsor: Annetine Gelijns

Sex: All·Age: 60+

Code: NCT05051033·Recruiting

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A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

for Non-Small Cell Lung Cancer

Drug: Durvalumab

43 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05211895·Phase 3·Recruiting

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Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

for Pruritus

Drug: Dupilumab

18 locations incl. Bakersfield

Sponsor: Sanofi

Sex: All·Age: 18 - 90

Code: NCT05263206·Phase 3·Recruiting

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Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors

for Solid Tumor

4 locations incl. Hackensack

Sponsor: Impact Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05269316·Phase 1, Phase 2·Recruiting

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Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

for Adenocarcinoma of the Colon

472 locations incl. Fairbanks

Sponsor: NRG Oncology

Sex: All·Age: 45 - 70

Code: NCT05080673·Recruiting

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Assessment of CCM in HF With Higher Ejection Fraction

for Heart Failure

105 locations incl. Birmingham

Sponsor: Impulse Dynamics

Sex: All·Age: 18+

Code: NCT05064709·Recruiting

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Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System

for Osteoarthritis Ankle

10 locations incl. Mission Hills

Sponsor: DT MedTech, LLC

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT04770870·Recruiting

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Weekly Sirolimus Therapy

for Venous Malformation

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 2+

Code: NCT04861064·Phase 2·Recruiting

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Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care

for Depression

1 location in Charleston

Sponsor: VA Office of Research and Development

Sex: All·Age: 21+

Code: NCT04877197·Phase 3·Recruiting

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Long-term Extension Study to Assess Safety and Tolerability of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Pediatric Participants (Ages 6-17)

for Migraine

Drug: Ubrogepant

109 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05127954·Phase 3·Enrolling By Invitation

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

for Migraine

Drug: Ubrogepant

125 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT05125302·Phase 3·Recruiting

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Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

for AMD

107 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 50 - 89

Code: NCT05407636·Phase 3·Recruiting

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Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract

for Cataract

9 locations incl. Huntington Beach

Sponsor: EyePoint Pharmaceuticals, Inc.

Sex: All·Age: Up to 3

Code: NCT05191706·Phase 4·Recruiting

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Blood Warming in Preterm Infants to Decrease Hypothermia

for Preterm Birth

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 24 Weeks - 32 Weeks·Accepts healthy volunteers

Code: NCT05170633·Recruiting

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Long-term Follow-up Study for Participants of Kite-Sponsored Interventional Studies Treated With Gene-Modified Cells

for Solid and Hematological Malignancies

49 locations incl. Gilbert

Sponsor: Kite, A Gilead Company

Sex: All·Age: All ages

Code: NCT05041309·Enrolling By Invitation

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

for Neovascular Age-related Macular Degeneration

Drug: Ranibizumab

50 locations incl. Mesa

Sponsor: Genentech, Inc.

Sex: All·Age: 50+

Code: NCT04853251·Phase 4·Recruiting

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Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

for Renal Cell Carcinoma (RCC)

46 locations incl. Phoenix

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT05176483·Phase 1·Recruiting

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Advanced SPinal Innovations With Robotics and Enabling Technology Registry

for Spine Deformity

10 locations incl. Los Angeles

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 21·Accepts healthy volunteers

Code: NCT05071144·Recruiting

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4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration

for Neovascular (Wet) Age-Related Macular Degeneration

24 locations incl. Phoenix

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 50+

Code: NCT05197270·Phase 1, Phase 2·Recruiting

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X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma

for Advanced Solid Tumor Cancer

4 locations incl. Washington D.C.

Sponsor: Immunolight, LLC

Sex: All·Age: 18+

Code: NCT04389281·Phase 1·Recruiting

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Optimizing Tobacco Treatment Delivery for People Living With HIV

for Hiv

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+

Code: NCT05019495·Recruiting

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Autologous Mesenchymal Stromal Cells and Islet Co-transplantation in TP-IAT

for Chronic Pancreatitis

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05095532·Phase 1·Recruiting

Apply to this trial