Oncology Clinical Trials in Sacramento, CA

As of June 2026, 126 paid clinical trials are recruiting for Oncology in Sacramento, California. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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126 clinical trials for Oncology

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A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for Carcinoma, Non-Small-Cell Lung

25 locations incl. Birmingham

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT05208762·Phase 1·Recruiting

Apply to this trial

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

for Prostate Cancer

32 locations incl. Birmingham

Sponsor: Janux Therapeutics

Sex: Male·Age: 18 - 100

Code: NCT05519449·Phase 1·Recruiting

Apply to this trial

Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer

for Lung Cancer

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT05452005·Phase 1·Recruiting

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Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

42 locations incl. Phoenix

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting

Apply to this trial

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

746 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting

Apply to this trial

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

for Locally Advanced Solid Tumor

21 locations incl. Orange

Sponsor: Nuvalent Inc.

Sex: All·Age: 12+

Code: NCT05384626·Phase 1, Phase 2·Recruiting

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

219 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting

Apply to this trial

Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML

for Myelodysplastic Syndromes

Drug: Venetoclax

3 locations incl. Sacramento

Sponsor: Montefiore Medical Center

Sex: All·Age: 18+

Code: NCT05184842·Phase 2·Recruiting

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Azacitidine or Decitabine With Venetoclax for Acute Myeloid Leukemia With Prior Hypomethylating Agent Failure

for Acute Myeloid Leukemia

Drug: Venetoclax

4 locations incl. Clovis

Sponsor: Brian Jonas

Sex: All·Age: 18+

Code: NCT04905810·Phase 2·Recruiting

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A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

for Locally Advanced Solid Tumor

20 locations incl. Orange

Sponsor: Nuvalent Inc.

Sex: All·Age: 12+

Code: NCT05118789·Phase 1, Phase 2·Recruiting

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Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

for Breast Cancer, NOS

347 locations incl. Fairbanks

Sponsor: Eastern Cooperative Oncology Group

Sex: All·Age: 18 - 39

Code: NCT05108298·Recruiting

Apply to this trial

A Cancer Vaccine (Labvax 3(22)-23) and GM-CSF Alone or in Combination With Pembrolizumab for the Treatment of Advanced Stage Adenocarcinoma

for Advanced Adenocarcinoma

1 location in Sacramento

Sponsor: Tianhong Li

Sex: All·Age: 18+

Code: NCT05101356·Phase 1, Phase 2·Recruiting

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Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

for Prostate Cancer

5 locations incl. Sacramento

Sponsor: University of British Columbia

Sex: Male·Age: 18+

Code: NCT04812366·Phase 2·Recruiting

Apply to this trial

Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

843 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting

Apply to this trial

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for Bladder Carcinoma

33 locations incl. Birmingham

Sponsor: Guardant Health, Inc.

Sex: All·Age: 18+

Code: NCT05059444·Recruiting

Apply to this trial

An Internet-based Program to Help Cancer Survivors Manage Pain

for Cancer

149 locations incl. Fort Smith

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT04462302·Recruiting

Apply to this trial

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

30 locations incl. Orange

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting

Apply to this trial

Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

387 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting

Apply to this trial

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

621 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting

Apply to this trial

Vyxeos for Re-induction Treatment of Acute Myeloid Leukemia Patients With Persistent Disease After Induction

for Blasts More Than 5 Percent of Bone Marrow Nucleated Cells

2 locations incl. Sacramento

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18 - 75

Code: NCT04049539·Phase 1, Phase 2·Recruiting

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A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

38 locations incl. Duarte

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT04302025·Phase 2·Recruiting

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Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

342 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting

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Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

45 locations incl. Phoenix

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

539 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting

Apply to this trial

Development of a Research Infrastructure for Understanding and Addressing Multiple Myeloma Disparities

for Multiple Myeloma

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 21+

Code: NCT04314752·Recruiting

Apply to this trial

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

Apply to this trial

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

1150 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting

Apply to this trial

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma

15 locations incl. La Jolla

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT04429542·Phase 1·Recruiting

Apply to this trial

Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial

for Prostate Adenocarcinoma

Drug: Apalutamide

345 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT04134260·Phase 3·Recruiting

Apply to this trial

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

Apply to this trial

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

Apply to this trial

A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

for Acute Myeloid Leukemia

11 locations incl. Duarte

Sponsor: Orca Biosystems, Inc.

Sex: All·Age: 12 - 78

Code: NCT03802695·Phase 1·Recruiting

Apply to this trial

Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia

for Leukemia, Myeloid, Acute

Drug: Tuspetinib

15 locations incl. Birmingham

Sponsor: Aptose Biosciences Inc.

Sex: All·Age: 18+

Code: NCT03850574·Phase 1, Phase 2·Recruiting

Apply to this trial

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

73 locations incl. Tucson

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting

Apply to this trial

Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

for Breast Cancer

451 locations incl. Fairbanks

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 35+

Code: NCT03488693·Phase 3·Recruiting

Apply to this trial

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for Neoplasms

100 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: All ages

Code: NCT03435796·Phase 2, Phase 3·Recruiting

Apply to this trial

A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)

for Renal Cell Carcinoma

14 locations incl. Phoenix

Sponsor: Xynomic Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT03592472·Phase 3·Recruiting

Apply to this trial

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

152 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting

Apply to this trial

Patient Satisfaction With Appearance, Scar Outcome and Quality of Life After Skin Cancer Surgery

for Skin Cancer

5 locations incl. Sacramento

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 21+

Code: NCT03503240·Enrolling By Invitation

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

for Head and Neck Squamous Cell Carcinoma

676 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT02734537·Phase 2·Recruiting

Apply to this trial

Conditions in Oncology (Sacramento, CA)

Solid tumor· 23 Non-small cell lung cancer (NSCLC)· 22 Breast cancer· 18 Acute myeloid leukemia (AML)· 12 Prostate cancer· 11 Head and neck cancer· 8 Cancer (any)· 7 Pancreatic cancer· 6 Multiple myeloma· 6 Diffuse large B-cell lymphoma (DLBCL)· 6 Kidney cancer· 5 Hematologic malignancy· 5 Colorectal cancer· 4 Ovarian cancer· 4 Myelodysplastic syndromes (MDS)· 4 Non-Hodgkin lymphoma· 4 Melanoma· 4 Lung cancer· 3 Gastric cancer· 3 Leukemia (other)· 3 Liver cancer· 2 Metastatic prostate cancer· 2 Bladder cancer· 2 Endometrial cancer· 2 Brain metastases· 2 Chronic lymphocytic leukemia (CLL)· 2 Chronic myelomonocytic leukemia· 2 Acute lymphoblastic leukemia· 2 Sarcoma· 2 Neuroblastoma· 2 Metastatic breast cancer· 1 Triple-negative breast cancer· 1 Rectal cancer· 1 Esophageal cancer· 1 Gastroesophageal junction cancer· 1 Glioblastoma· 1 Myelofibrosis· 1 Myeloproliferative neoplasm· 1 Hodgkin lymphoma· 1 Small lymphocytic lymphoma· 1 Skin cancer· 1 Osteosarcoma· 1 Neuroendocrine tumors· 1