Non-small cell lung cancer (NSCLC) Clinical Trials in Sacramento, CA
As of June 2026, 22 paid clinical trials are recruiting for Non-small cell lung cancer (NSCLC) in Sacramento, California. Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Sacramento
Filter results
22 clinical trials for Non-small cell lung cancer (NSCLC)
·Clear filters·↓ Download CSVRisk-adapted, Proteomic-guided Systemic Therapy for Previously Untreated Advanced Non-small Cell Lung Cancer
EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
A Study of the Oral EGFR Inhibitor PLB1004 in Non-Small Cell Lung Cancer
Osimertinib, Cetuximab, and Tucatinib for the Treatment of EGFR-Mutant Stage IV or Recurrent Non-small Lung Cell Cancer
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
LOcally ABLatIve ThErapy for OligopRogressive Lung And Thoracic MalignanciEs (OBLITERATE)
Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
About research studies in Sacramento
Sacramento has approximately 616 recruiting research studies across a wide range of therapeutic areas. California hosts a dense network of world-class research institutions, including UC San Diego Health, Stanford Medicine, UCLA Health, UCSF, City of Hope, and Scripps Research. The state's thriving biotech corridor and diverse patient population make it a national hub for both early-phase and late-phase clinical research.
Top Research Study Locations in Sacramento
Researchers run research studies in Sacramento, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of California Davis Comprehensive Cancer Center | Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, Advanced Malignant Solid Neoplasm | 105 |
| Mercy Cancer Center - Sacramento | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer | 44 |
| Sutter Medical Center Sacramento | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 38 |
| UC Davis Medical Center | Heart Failure, Intracerebral Hemorrhage, Acute Decompensated Heart Failure | 37 |
| University of California, Davis | Oligoprogressive, Amblyopia, Amyotrophic Lateral Sclerosis | 36 |
| Kaiser Permanente-South Sacramento | Stage IIIB Lung Cancer AJCC v8, Breast Cancer, Acute Myeloid Leukemia | 35 |
| Kaiser Permanente Downtown Commons | Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Breast Cancer | 34 |
| UC Davis Health | Heart Failure, Acute Pain, Anterior Cruciate Ligament Rupture | 23 |
| University of California Davis | Adenovirus Infections, Advanced Lung Carcinoma, Breast Cancer | 20 |
| South Sacramento Cancer Center | Breast Cancer, Ovarian Carcinoma, Stage II Lung Cancer AJCC v8 | 16 |
| UC Davis | Von Willebrand Disease, Type 3, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 15 |
| University of California Davis Health | Articular Cartilage Defect, Articular Cartilage Disorder of Knee, COVID-19 Infection | 12 |
| University of California Davis Medical Center | Abdominal Aortic Aneurysm, Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder), Abdominal Aortic Aneurysm >= 5.5 Centimeters in Male (Disorder) | 12 |
| University of California, Davis Comprehensive Cancer Center | Advanced Solid Tumor, Locally Advanced Solid Tumor, Metastatic Solid Tumor | 11 |
| Sutter Institute for Medical Research | Acute Ischemic Stroke, Bladder Carcinoma, Breast Cancer | 9 |
| University of California, Davis Medical Center | Abdomen Injury, Abdomen, Acute, Abdominal Injury | 9 |
| UC Davis Comprehensive Cancer Center | Abdominal Neoplasm, Advanced Solid Tumors, Avascular Necrosis | 8 |
| University of California, Davis - Dermatology Department | Scarring, Actinic Keratoses, Alopecia Areata | 8 |
| Kaiser Permanente Sacramento Medical Center | Atrial Fibrillation, B Acute Lymphoblastic Leukemia, Intracerebral Hemorrhage | 8 |
| UC Davis MIND Institute | ADHD, Attention Deficit Hyperactivity Disorder, Down Syndrome | 7 |
| Integrative Skin Science and Research | Atopic Dermatitis, Atopic, Collagen Degeneration | 6 |
| Retinal Consultants Medical Group | Diabetic Macular Edema, Geographic Atrophy, Age-Related Macular Degeneration | 6 |
| University of California Davis Health System | COVID-19, Coagulation Disorder, Coronary Artery Disease | 6 |
| UC Davis Children's Hospital | Abdominal Pain, Ductus Arteriosus, Patent, Gastroschisis | 5 |
| UC Davis EXPLORER Molecular Imaging Center | Breast Cancer, Cardiovascular Disease, Chronic Low-back Pain (cLBP) | 5 |
Active & Upcoming Studies in Sacramento (2026)
Recruiting trials in Sacramento grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (213 active studies)
- Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation · Phase 1, Phase 2 · National Cancer Institute (NCI)
- Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia · Phase 2 · National Cancer Institute (NCI)
Neurology & pain (35 active studies)
- Morphine or Ketamine for Analgesia · Phase 3 · Columbia University
- A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT). · Phase 3 · Eli Lilly and Company
Cardiovascular (28 active studies)
- Reduction of Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US) · InnovHeart
- Dopamine vs. Norepinephrine for Hypotension in Neonates With Pulmonary Hypertension (DONE) · Phase 4 · University of California, Davis
Eye & vision (24 active studies)
- A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated · Phase 1, Phase 2 · Boehringer Ingelheim
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
Diabetes & metabolic (17 active studies)
- Pregnancy and Postpartum Breastfeeding Support for Patients With Gestational Diabetes · University of California, Davis
- A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin · Phase 3 · Eli Lilly and Company
Mental health & behavior (7 active studies)
- Sham-Controlled Rapid-Acting Neuromodulation for Depression · University of California, Davis
- ALTO-207 in Adults With Treatment-resistant Depression (TRD) · Phase 2 · Alto Neuroscience
Vaccines (4 active studies)
- Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC) · EARLY_Phase 1 · University of California, Davis
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
HIV / STI (3 active studies)
- T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL) · Phase 1, Phase 2 · Estrella Biopharma, Inc.
- Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure) · Phase 2 · GlaxoSmithKline
Pediatric (3 active studies)
- A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) · Phase 3 · Janssen Research & Development, LLC
- Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS · Phase 2, Phase 3 · Nationwide Children's Hospital
Common conditions studied in Sacramento
- Breast Cancer (13 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Acute Myeloid Leukemia (11 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Heart Failure (11 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Atopic Dermatitis (10 active studies). Atopic dermatitis studies test IL-13 inhibitors, JAK inhibitors, and next-generation topical therapies for moderate-to-severe eczema.
- Stage IV Lung Cancer AJCC v8 (9 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Prostate Cancer (7 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
Leading research sponsors in Sacramento
- University of California, Davis
- National Cancer Institute (NCI)
- NRG Oncology
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
Local regulations and guidelines
Clinical trials in California are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. In addition, California-specific protections such as the California Consumer Privacy Act (CCPA) and the Confidentiality of Medical Information Act (CMIA) impose stringent data-privacy requirements on research involving California residents.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Sacramento. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Sacramento
Hipa.ai aggregates every recruiting study in Sacramento from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Sacramento?
There are approximately 616 recruiting clinical trials in Sacramento, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Sacramento pay participants?
Most recruiting trials in Sacramento compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Sacramento?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Sacramento?
The most common conditions under active study in Sacramento include Breast Cancer (13), Acute Myeloid Leukemia (11), Heart Failure (11), Atopic Dermatitis (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Sacramento?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Sacramento on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Sacramento?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Sacramento?
Recruiting research sites in Sacramento include University of California Davis Comprehensive Cancer Center, Mercy Cancer Center - Sacramento, Sutter Medical Center Sacramento, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Sacramento right now?
The largest active categories in Sacramento are Cancer & tumors (213), Neurology & pain (35), Cardiovascular (28). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.