Paid Clinical Trials in Philadelphia, PA

As of June 2026, 2,101 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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2,101 clinical trials

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PET Tau - Neurodegenerative Disease Imaging

for Neurodegenerative Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT03143374·Phase 2, Phase 3·Recruiting

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Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients With Recurrent or Progressive Grade 2 or 3 Meningioma

for Anaplastic (Malignant) Meningioma

Drug: Bevacizumab

8 locations incl. Santa Monica

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT02847559·Phase 2·Recruiting

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COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

for Complex Congenital Heart Defect

25 locations incl. Little Rock

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT02744677·Recruiting

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Prospective Research Rare Kidney Stones (ProRKS)

for Hyperoxaluria

8 locations incl. Birmingham

Sponsor: Mayo Clinic

Sex: All·Age: All ages

Code: NCT02780297·Recruiting

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National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

61 locations incl. Birmingham

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting

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Quality of Pediatric Resuscitation in a Multicenter Collaborative

for Cardiac Arrest

40 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 18

Code: NCT02708134·Recruiting

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PENN-Surveillance Markers of Utility for Recurrence After (Neo)Adjuvant Therapy for Breast Cancer

for Breast Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT02732171·Recruiting

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Autoimmune Blistering Diseases Study

for Pemphigus Vulgaris

3 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT02753777·Recruiting

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TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

for Lymphoma, Non-Hodgkin

174 locations incl. Birmingham

Sponsor: American Society of Clinical Oncology

Sex: All·Age: 12+

Code: NCT02693535·Phase 2·Recruiting

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Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)

for Congenital Central Hypoventilation Syndrome

4 locations incl. Los Angeles

Sponsor: Debra Weese-Mayer

Sex: All·Age: 3 - 85

Code: NCT03568669·Recruiting

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TSC Biosample Repository and Natural History Database

for Tuberous Sclerosis

24 locations incl. Birmingham

Sponsor: National Tuberous Sclerosis Association

Sex: All·Age: All ages

Code: NCT05676099·Recruiting

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Evaluation of Outcome Metrics in Alexander Disease

for Alexander Disease

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT02714764·Recruiting

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Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT

for Suspected Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT02637934·Phase 1·Recruiting

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Fecal Microbiome Transplant

for Clostridium Difficile

1 location in Philadelphia

Sponsor: Judith Kelsen

Sex: All·Age: 3 - 21

Code: NCT02636517·Phase 1·Enrolling By Invitation

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

for Neurofibromatosis 1

6 locations incl. Washington D.C.

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5+·Accepts healthy volunteers

Code: NCT02544022·Recruiting

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

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CAR-T Long Term Follow Up (LTFU) Study

for Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program

44 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 0 - 100

Code: NCT02445222·Phase 3·Recruiting

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KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children

for Acute Lymphoblastic Leukemia

11 locations incl. Los Angeles

Sponsor: Michael Pulsipher

Sex: All·Age: Up to 21

Code: NCT02646839·Phase 2·Enrolling By Invitation

Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

52 locations incl. Phoenix

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting

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Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

for Intracranial Meningioma

780 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT02523014·Phase 2·Recruiting

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Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

for Genetic Disease

33 locations incl. Birmingham

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Month - 100·Accepts healthy volunteers

Code: NCT02450851·Recruiting

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Protocol to Permit the Acquisition of Circulating Tumor Material in Pancreatic Diseases

for Pancreatic Diseases

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT02471170·Enrolling By Invitation

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

75 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting

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JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

for Non-Small Cell Lung Cancer

40 locations incl. La Jolla

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT02468024·Phase 3·Recruiting

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Total Shoulder Arthroplasty Multi-Center Registry

for Shoulder Arthroplasty

22 locations incl. Phoenix

Sponsor: Arthrex, Inc.

Sex: All·Age: 18 - 100

Code: NCT03511586·Recruiting

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OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages

for Eosinophilic Gastrointestinal Disorders (EGIDs)

19 locations incl. Phoenix

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 3+

Code: NCT02523118·Recruiting

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Clinical Outcomes Study of the Nexel Total Elbow

for Elbow Joint Destruction

4 locations incl. Golden

Sponsor: Zimmer Biomet

Sex: All·Age: 18+

Code: NCT02469662·Recruiting

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Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

for Pancreatic Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT02478892·Recruiting

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Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

for Focal Segmental Glomerulosclerosis

12 locations incl. Loma Linda

Sponsor: Kaneka Medical America LLC

Sex: All·Age: Up to 21

Code: NCT02235857·Recruiting

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C-Brace Prospective Registry

for Pareses

70 locations incl. Harrison

Sponsor: Otto Bock Healthcare Products GmbH

Sex: All·Age: All ages

Code: NCT04640584·Recruiting

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ALS/MND Natural History Study Data Repository

for ALS

14 locations incl. Loma Linda

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting

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Safety and Durability of Sirolimus for Treatment of LAM

for Lymphangioleiomyomatosis

20 locations incl. Stanford

Sponsor: University of Cincinnati

Sex: Female·Age: 18+

Code: NCT02432560·Recruiting

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Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

for HIV Infection

20 locations incl. La Jolla

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: Up to 48 Hours

Code: NCT02140255·Phase 1, Phase 2·Recruiting

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Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry

for Pulmonary Vascular Disease

13 locations incl. Palo Alto

Sponsor: New York Medical College

Sex: All·Age: 1 Day - 21

Code: NCT02249923·Recruiting

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Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer

for Hepatocellular Carcinoma

2 locations incl. Palo Alto

Sponsor: Teclison Ltd.

Sex: All·Age: 20 - 99

Code: NCT02174549·Phase 1, Phase 2·Recruiting

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Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

for Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease

44 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT01915511·Recruiting

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Osteochondritis Dissecans of Knee Prospective Cohort

for Osteochondritis Dissecans

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT02771496·Recruiting

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Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer

for Carcinoma, Hepatocellular

9 locations incl. San Francisco

Sponsor: Baylor Research Institute

Sex: All·Age: 18+

Code: NCT02081755·Phase 4·Enrolling By Invitation

Evaluation of the PACE/PACENET BHL Clinical Program

for Depression

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 65+

Code: NCT02463266·Recruiting

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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for Hodgkin Lymphoma in Remission

69 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT01790152·Recruiting

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