Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

Part of paid clinical trials in Philadelphia, Pennsylvania.

Sponsor
Abramson Cancer Center at Penn Medicine
Study ID
NCT02478892
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Collection of data from endoscopic ultrasound or MRI/MRCP of the abdomen — OTHER
    Participants in this study should be undergoing pancreatic cancer screening with endoscopic ultrasound or MRI as part of their standard care. These should typically be done at least every 12 months, and the imaging tests will be ordered as routine clinical tests and will be billed to the participant's insurance. This study does not cover the costs of these screening tests, however the study will track the results of these screening tests.
  • Blood sample collection for research — OTHER
    Up to 40mL of blood may be collected for analysis at each screening examination.

Study Details

The study is a prospective, observational study evaluating the utility of endoscopic ultrasound or MRI for the identification of preneoplastic and neoplastic pancreatic lesions in patients at high risk for pancreatic cancer, specifically those with BRCA1/2, ATM, or PALB2 mutations.

Key Dates

Start date
May 31, 2015
Status verified
Feb 2026
Primary completion
May 31, 2028
Completion
May 31, 2030

Study Design

Enrollment
200 participants (estimated)

Primary Outcome Measure

identifying pancreatic neoplastic lesions lesions in patients with BRCA1/2 mutations and other less common, but related mutations (ATM, PALB2) as well as mutations identified in the future. [ Time Frame: 10 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Abramson Cancer Center of the University of PennsylvaniaPhiladelphiaPennsylvania19004
Bryson Katona, MD
[email protected]
855-216-0098
Bryson Katona, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Philadelphia, PA

By condition
Pancreatic cancer
By specialty
OncologyGI oncology
By research site
Abramson Cancer Center of the University of Pennsylvania· Philadelphia, PA

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