JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

Part of paid clinical trials in La Jolla, California.

Sponsor
University of Texas Southwestern Medical Center
Study ID
NCT02468024
Phase
PHASE3
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Lung Surgery — PROCEDURE
    Sublobar Lung Resection
  • Radiation therapy — RADIATION
    Stereotactic Ablative Radiotherapy, 54 Gy in 3 fractions

Study Details

To Determine if SAbR improves survival over SR in High Risk Operable Stage I NSCLC

Key Dates

Start date
Jul 31, 2015
Status verified
Apr 2026
Primary completion
Dec 31, 2028
Completion
Dec 31, 2028

Study Design

Enrollment
272 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Arm 1 lung surgery
    Sublobar Resection (SR)
  • Experimental: Arm 2 radiation therapy
    Stereotactic Ablative Radiotherapy (SAbR)

Primary Outcome Measure

overall survival [ Time Frame: 3 years ]

Central Contacts

Locations (40)

FacilityCityStateZIPSite coordinators
UCSDLa JollaCalifornia92023-
University of Colorado/MemorialAuroraColorado80045-
Penrose Cancer CenterColorado SpringsColorado80907-
Boca Raton Regional HospitalBoca RatonFlorida33486-
Curtis and Elizabeth Anderson CancerSavannahGeorgia31404
Aaron Pederson, MD
912-350-8490
University of IowaIowa CityIowa52242-
University of Kansas Medical CenterKansas CityKansas66160-
University of Kentucky Health CareLexingtonKentucky40536-0093-
University of Louisville PhysiciansLouisvilleKentucky40202-
Ochsner Medical CenterNew OrleansLouisiana70121-
Luminis Health Research InstituteAnnapolisMaryland21401-
University of Maryland Medical CenterBaltimoreMaryland21201-
Boston Medical CenterBostonMassachusetts02118-
Henry Ford Health SystemDetroitMichigan48202-2689-
BeaumontRoyal OakMichigan48073-
Mayo Clinic RochesterRochesterMinnesota55905-
Meridian Health SystemNeptune CityNew Jersey07753
Thomas Bauer, MD
[email protected]
New York University Langone Medical CenterNew YorkNew York10016-
SUNY - Upsate Medical CentreSyracuseNew York13210
Jeffrey Bogart, MD
[email protected]
Erin Bingham
[email protected]
University of North CarolinaChapel HillNorth Carolina27599-
Wake Forest Baptist HealthWinston-SalemNorth Carolina27157-
University of CincinnatiCincinnatiOhio45267-
Case Western (University Hospitals Case Medical Center)ClevelandOhio44106-
Cleveland ClinicClevelandOhio44195-
Ohio State University Wexner Medical CenterColumbusOhio43210-
Providence Health & Services/Oregon ClinicPortlandOregon97213-
Thomas Jefferson UniversityPhiladelphiaPennsylvania19107-
AlleghenyPittsburghPennsylvania15212
Benny Weksler, MD
[email protected]
UPMC Health SystemPittsburghPennsylvania15234-
Mount NittanyState CollegePennsylvania16803-
Lifespan Oncology Clinical ResearchProvidenceRhode Island02903-
University of Tennessee Health Science CenterMemphisTennessee38163-
Cardiothoracic and Vascular SurgeonsAustinTexas78756-
University of Texas Southwestern Medical CenterDallasTexas75390
Robert Timmerman, MD
214-645-8525
Robert Timmerman, MD (PRINCIPAL_INVESTIGATOR)
Intermountain Medical CenterSalt Lake CityUtah84107-
University of Virginia Health SystemCharlottesvilleVirginia22901-
Inova Fairfax Medical CampusFalls ChurchVirginia22042-
Swedish Cancer InstituteSeattleWashington98104-
Clement Zablocki VA Medical CenterMilwaukeeWisconsin53295-
Medical College of WisconsinMilwaukeeWisconsin53226-

Find similar trials in La Jolla, CA

By condition
Lung cancer
By specialty
OncologyLung oncologyLung disease
By research site
UCSD· La Jolla, CAUniversity of Colorado/Memorial· Aurora, COPenrose Cancer Center· Colorado Springs, COBoca Raton Regional Hospital· Boca Raton, FLCurtis and Elizabeth Anderson Cancer· Savannah, GAUniversity of Iowa· Iowa City, IA

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