Clinical Trials at Children's Hospital of Philadelphia

As of June 2026, 308 paid clinical trials are recruiting at Children's Hospital of Philadelphia, located at 3550 MARKET ST, 5TH FLOOR, PHILADELPHIA, PA 19104-3329, phone (215) 590-4862 in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

308 clinical trials at Children's Hospital of Philadelphia

·Clear filters·↓ Download CSV

National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

61 locations incl. Birmingham

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting

Apply to this trial

Quality of Pediatric Resuscitation in a Multicenter Collaborative

for Cardiac Arrest

40 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 18

Code: NCT02708134·Recruiting

Apply to this trial

Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)

for Congenital Central Hypoventilation Syndrome

4 locations incl. Los Angeles

Sponsor: Debra Weese-Mayer

Sex: All·Age: 3 - 85

Code: NCT03568669·Recruiting

Apply to this trial

Evaluation of Outcome Metrics in Alexander Disease

for Alexander Disease

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT02714764·Recruiting

Apply to this trial

Fecal Microbiome Transplant

for Clostridium Difficile

1 location in Philadelphia

Sponsor: Judith Kelsen

Sex: All·Age: 3 - 21

Code: NCT02636517·Phase 1·Enrolling By Invitation

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

for Neurofibromatosis 1

6 locations incl. Washington D.C.

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5+·Accepts healthy volunteers

Code: NCT02544022·Recruiting

Apply to this trial

Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

Apply to this trial

KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children

for Acute Lymphoblastic Leukemia

11 locations incl. Los Angeles

Sponsor: Michael Pulsipher

Sex: All·Age: Up to 21

Code: NCT02646839·Phase 2·Enrolling By Invitation

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

for Genetic Disease

33 locations incl. Birmingham

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Month - 100·Accepts healthy volunteers

Code: NCT02450851·Recruiting

Apply to this trial

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

75 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting

Apply to this trial

OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages

for Eosinophilic Gastrointestinal Disorders (EGIDs)

19 locations incl. Phoenix

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 3+

Code: NCT02523118·Recruiting

Apply to this trial

Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry

for Pulmonary Vascular Disease

13 locations incl. Palo Alto

Sponsor: New York Medical College

Sex: All·Age: 1 Day - 21

Code: NCT02249923·Recruiting

Apply to this trial

Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC

for Leukemia

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 30

Code: NCT02356653·EARLY_Phase 1·Recruiting

Apply to this trial

Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease

for Legg Calve Perthes Disease

28 locations incl. Birmingham

Sponsor: Texas Scottish Rite Hospital for Children

Sex: All·Age: 1 - 18

Code: NCT02040714·Enrolling By Invitation

Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

71 locations incl. Birmingham

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting

Apply to this trial

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

142 locations incl. Birmingham

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting

Apply to this trial

Neuroblastoma Biology Study

for Neuroblastoma

16 locations incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 31 Days - 99

Code: NCT01587300·Recruiting

Apply to this trial

ARPKD Database Study

for Hepato/Renal Fibrocystic Disease

6 locations incl. Washington D.C.

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 18

Code: NCT01401998·Recruiting

Apply to this trial

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

for Charcot-Marie-Tooth Disease, Type Ia (Disorder)

17 locations incl. Los Angeles

Sponsor: University of Iowa

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01193088·Recruiting

Apply to this trial

Nephrotic Syndrome Study Network

for Minimal Change Disease (MCD)

39 locations incl. Los Angeles

Sponsor: University of Michigan

Sex: All·Age: Up to 80

Code: NCT01209000·Recruiting

Apply to this trial

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

for Charcot Marie Tooth Disease

18 locations incl. Los Angeles

Sponsor: Michael Shy

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01193075·Recruiting

Apply to this trial

Biliary Atresia Study in Infants and Children

for Biliary Atresia

15 locations incl. Los Angeles

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 6 Months - 20

Code: NCT00345553·Recruiting

Apply to this trial

Longitudinal Study of Urea Cycle Disorders

for Brain Diseases, Metabolic, Inborn

12 locations incl. Los Angeles

Sponsor: Andrea Gropman

Sex: All·Age: All ages

Code: NCT00237315·Recruiting

Apply to this trial

Pompe Disease Registry Protocol

for Glycogen Storage Disease Type II

93 locations incl. Birmingham

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00231400·Recruiting

Apply to this trial

A Prospective Database of Infants With Cholestasis

for Biliary Atresia

15 locations incl. Los Angeles

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: Up to 6 Months

Code: NCT00061828·Recruiting

Apply to this trial

Fabry Disease Registry & Pregnancy Sub-registry

for Fabry Disease

92 locations incl. Birmingham

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00196742·Recruiting

Apply to this trial

Childhood Cancer Survivor Study

for Cancer

30 locations incl. Birmingham

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting

Apply to this trial

International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

for Gaucher Disease

86 locations incl. Phoenix

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00358943·Recruiting

Apply to this trial