Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,674 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,674 clinical trials

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PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial

for Lung Carcinoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05775939·Recruiting

Apply to this trial

Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)

for Pulmonary Arterial Hypertension

10 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 1 - 17

Code: NCT05587712·Phase 2·Recruiting

Apply to this trial

Posterior Cingulate Cortex and Executive Control of Episodic Memory

for Episodic Memory

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 50

Code: NCT06540976·Recruiting

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Validation of Oxygen Nanosensor in Mitochondrial Myopathy

for Mitochondrial Myopathies

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT04086329·Phase 1·Recruiting

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Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

for Gastric Cancer

11 locations incl. Los Angeles

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05702229·Phase 2·Recruiting

Apply to this trial

WBSI Guided Personalized Delivery of TTFields

for GBM

2 locations incl. Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 22+

Code: NCT05086497·Recruiting

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Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

for Multiple Sclerosis

12 locations incl. New Haven

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55

Code: NCT05285891·Phase 4·Recruiting

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FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

for Urinary Bladder Neoplasms

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05614739·Phase 1·Recruiting

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Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)

for Mesotheliomas Pleural

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT03760575·Phase 1·Recruiting

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Alleviant ALLAY-HF Study

for Heart Failure

53 locations incl. Birmingham

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 40+

Code: NCT05685303·Enrolling By Invitation

Treatment for Problematic Sexual Behavior of Preteen Children

for Problematic Sexual Behavior Among Preteen Children

1 location in Harrisburg

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 4 - 12

Code: NCT05514730·Recruiting

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Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

for Acute Gout Flare

25 locations incl. Birmingham

Sponsor: Olatec Therapeutics LLC

Sex: All·Age: 18+

Code: NCT05658575·Phase 2, Phase 3·Recruiting

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DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis

for Venous Thromboembolism

48 locations incl. Scottsdale

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT05701917·Recruiting

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Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

for Abdominal Aortic Aneurysm

32 locations incl. Loma Linda

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 20+

Code: NCT05378347·Recruiting

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taVNS for FRNS in Children

for Nephrotic Syndrome in Children

2 locations incl. New Hyde Park

Sponsor: Northwell Health

Sex: All·Age: 3 - 17

Code: NCT05588063·Recruiting

Apply to this trial

The Effects of Medicaid Policy Interventions on Racial Equity in Severe Maternal Morbidity

for Severe Maternal Morbidity

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05678699·Recruiting

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A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

for Autoimmune Diseases

12 locations incl. Orange

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06587828·Recruiting

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Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study

for Pain, Chronic

5 locations incl. Phoenix

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT05612750·Recruiting

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A Long-Term Follow-Up Study in Severe Hemophilia A Subjects Who Received BMN 270 in a Prior BioMarin Clinical Trial (270-401)

for Hemophilia A

13 locations incl. Los Angeles

Sponsor: BioMarin Pharmaceutical

Sex: Male·Age: 18+

Code: NCT05768386·Enrolling By Invitation

Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema

for Hereditary Angioedema

13 locations incl. Birmingham

Sponsor: Pharvaris Netherlands B.V.

Sex: All·Age: 12+

Code: NCT05396105·Phase 2, Phase 3·Enrolling By Invitation

Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B Respectively

for Hemophilia A

14 locations incl. Rancho Cordova

Sponsor: Pfizer

Sex: Male·Age: 18+

Code: NCT05568719·Phase 3·Recruiting

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Safety Extension Study for Subjects With HR+, HER2- Breast Cancer for Subjects Who Have Completed the OVELIA Study

for Breast Cancer

17 locations incl. Greenbrae

Sponsor: Tolmar Inc.

Sex: All·Age: 18 - 51

Code: NCT05645536·Phase 3·Enrolling By Invitation

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

for Atrial Fibrillation (AF)

Drug: Abelacimab

150 locations incl. Birmingham

Sponsor: Anthos Therapeutics, Inc.

Sex: All·Age: 65+

Code: NCT05712200·Phase 3·Recruiting

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Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

for Cervical Cancer

8 locations incl. Chicago

Sponsor: Orano Med Theranostics, SAS

Sex: All·Age: 18+

Code: NCT05283330·Phase 1·Recruiting

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PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

for Critical Limb Ischemia

30 locations incl. La Jolla

Sponsor: LimFlow, Inc.

Sex: All·Age: 18 - 95

Code: NCT05313165·Recruiting

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A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant

for Graft-Versus-Host Disease

9 locations incl. Bethesda

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 4+

Code: NCT05675930·Phase 2·Recruiting

Apply to this trial

EXploring Inflammation and Social deTerminants Study in Breast Cancer Patients

for Breast Cancer

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+

Code: NCT07478016·Recruiting

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Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)

for Advanced Melanoma

Drug: Tebentafusp

25 locations incl. Phoenix

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT05549297·Phase 3·Recruiting

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Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

for Endometrial Cancer

68 locations incl. Anchorage

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 18+

Code: NCT05640999·Phase 2·Recruiting

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Beta-blocker Administration for Cardiomyocyte Division

for Tetralogy of Fallot

3 locations incl. New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 30 Days - 60 Days

Code: NCT04713657·Phase 1·Recruiting

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Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control

for Movement Disorders (Incl Parkinsonism)

1 location in Pittsburgh

Sponsor: Jorge Gonzalez-Martinez

Sex: All·Age: 18 - 75

Code: NCT07056361·Recruiting

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Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

for Lung Adenocarcinoma

34 locations incl. Buena Park

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05198830·Phase 2·Recruiting

Apply to this trial

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

for Hematopoietic Cell Transplant

27 locations incl. Birmingham

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: Up to 18

Code: NCT05550298·Recruiting

Apply to this trial

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

for Viral Lung Infection and Acute Respiratory Failure

68 locations incl. Mobile

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05624450·Phase 3·Recruiting

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Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease

for Primary Mitochondrial Disease

20 locations incl. Orange

Sponsor: Abliva AB

Sex: All·Age: 18+

Code: NCT05650229·Phase 2·Recruiting

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Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

for Triple Negative Breast Cancer

184 locations incl. Birmingham

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05633654·Phase 3·Recruiting

Apply to this trial

Angiotensin-(1-7) Cardiovascular Effects in Aging

for Aging

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 65 - 80·Accepts healthy volunteers

Code: NCT05301192·EARLY_Phase 1·Recruiting

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A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC)

for Non Small Cell Lung Cancer

9 locations incl. Miami

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT05657873·Phase 2·Recruiting

Apply to this trial

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

for High Grade Epithelial Ovarian Cancer

37 locations incl. Phoenix

Sponsor: Genmab

Sex: All·Age: 18+

Code: NCT05579366·Phase 1, Phase 2·Recruiting

Apply to this trial

Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer

for Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8

55 locations incl. Washington D.C.

Sponsor: NRG Oncology

Sex: Female·Age: 18+

Code: NCT05646316·Phase 3·Recruiting

Apply to this trial