A Long-Term Follow-Up Study in Severe Hemophilia A Subjects Who Received BMN 270 in a Prior BioMarin Clinical Trial (270-401)

Part of paid clinical trials in Los Angeles, California.

Sponsor
BioMarin Pharmaceutical
Study ID
NCT05768386
Status
Enrolling By Invitation

Conditions

  • Hemophilia A

Eligibility Criteria

Sex
MALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

The BMN 270 clinical development program consists of multiple interventional studies designed to assess the safety and efficacy of a single infusion of BMN 270 for at least 5 years post-infusion. This long-term follow-up study is needed to help further understand the long-term safety of BMN 270 beyond 5 years and to assess the durability of efficacy.

Key Dates

Start date
Jan 1, 2023
Status verified
Jan 2026
Primary completion
Jan 31, 2040
Completion
Jan 31, 2040

Study Design

Enrollment
172 participants (estimated)

Primary Outcome Measure

Evaluate the long-term safety of BMN 270 [ Time Frame: Duration of study (10 years) ]

Locations (13)

FacilityCityStateZIPSite coordinators
Orthopedic Institute for Children, Orthopedic Hemophilia Treatment CenterLos AngelesCalifornia90007-
UC Davis Hemophilia Treatment CenterSacramentoCalifornia95817-
University of California San Diego, Hemophilia & Thrombosis Treatment CenterSan DiegoCalifornia92121-
University of California San Francisco - Moffit Hospital, Outpatient Hematology ClinicSan FranciscoCalifornia94143-
UCN Hemophilia and Thrombosis CenterShandonCalifornia27517-
Hemophilia and Thrombosis Center at the University of Colorado Anschutz Medical CampusAuroraColorado80045-
St Joseph's Children's Hospital, Center for Bleeding and Clotting DisordersTampaFlorida33614-
University Medical Center, Inc,; DBA University of Louisville Hospital, James Graham Brown Cancer CenterLouisvilleKentucky40202-3229-
University of Michigan, Pediatric Hematology and OncologyAnn ArborMichigan48109-5718-
Children's Hospital of Michigan, Hemophilia and Thrombosis CenterDetroitMichigan48201-
Washington University School of Medicine, Department of Pediatrics, Division of Hematology/OncologySt LouisMissouri63110-1093-
Nationwide Children's HospitalColumbusOhio43205-
Hemophilia Center of Western PennsylvaniaPittsburghPennsylvania15213-

Find similar trials in Los Angeles, CA

By research site
Orthopedic Institute for Children, Orthopedic Hemophilia Treatment Center· Los Angeles, CAUC Davis Hemophilia Treatment Center· Sacramento, CAUniversity of California San Diego, Hemophilia & Thrombosis Treatment Center· San Diego, CAUniversity of California San Francisco - Moffit Hospital, Outpatient Hematology Clinic· San Francisco, CAUCN Hemophilia and Thrombosis Center· Shandon, CAHemophilia and Thrombosis Center at the University of Colorado Anschutz Medical Campus· Aurora, CO

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