Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,677 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,674 clinical trials

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Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab

for Advanced Solid Tumor

6 locations incl. Scottsdale

Sponsor: Strand Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06249048·Phase 1, Phase 2·Recruiting

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Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty

for Osteoarthritis of Shoulder

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 45+

Code: NCT03921944·Recruiting

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Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents

for Acute Myeloid Leukemia

Drug: Venetoclax

7 locations incl. Miami

Sponsor: Joshua Zeidner

Sex: All·Age: 18+

Code: NCT05442216·Phase 2·Recruiting

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Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease

for Cirrhosis, Liver

2 locations incl. Ann Arbor

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06136221·Recruiting

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A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)

for Cataract

12 locations incl. Chico

Sponsor: Melt Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT06383273·Phase 3·Recruiting

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NICU Antibiotics and Outcomes (NANO) Follow-up Study

for Premature Birth

14 locations incl. San Diego

Sponsor: Sharp HealthCare

Sex: All·Age: 23 Weeks - 30 Weeks

Code: NCT05977400·Phase 3·Not Yet Recruiting

A Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)

for Homocystinuria

13 locations incl. Phoenix

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 5 - 65

Code: NCT06431893·Phase 3·Enrolling By Invitation

A Mechanistic Trial of the Neurobiology of Extinction Learning and Intraparietal Sulcus Stimulation

for Posttraumatic Stress Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 60

Code: NCT06234969·Recruiting

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A Study to Investigate the Pharmacokinetics and Safety of Risdiplam in Infants With Spinal Muscular Atrophy

for Muscular Atrophy, Spinal

3 locations incl. Chicago

Sponsor: Hoffmann-La Roche

Sex: All·Age: Up to 19 Days

Code: NCT05808764·Phase 2·Recruiting

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A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)

for Perennial Allergic Rhinitis (PAR)

27 locations incl. Huntington Beach

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06339008·Phase 3·Recruiting

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A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

for Hypothyroidism

134 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06345339·Phase 2, Phase 3·Recruiting

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Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol

for Binge-Eating Disorder

Drug: Solriamfetol

45 locations incl. Encino

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 55

Code: NCT06413433·Phase 3·Recruiting

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Cardiovascular Effects of a Healthy Dietary Pattern Containing Eggs

for Cardiovascular Diseases

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 30 - 60·Accepts healthy volunteers

Code: NCT06120400·Phase 3·Recruiting

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Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment

for Prostate Cancer

46 locations incl. Antioch

Sponsor: Canadian Cancer Trials Group

Sex: Male·Age: 18+

Code: NCT06235697·Phase 3·Recruiting

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Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma

for Esophageal Adenocarcinoma

2 locations incl. New York

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18+

Code: NCT06340711·Phase 2·Recruiting

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Acoustic Stimulation, Sleep, and Cognitive-Emotional Processes in Young Adults With Anxiety and Depression Symptoms

for Acoustic Stimulation

1 location in Pittsburgh

Sponsor: Michelle Stepan

Sex: All·Age: 18 - 25

Code: NCT05802004·Recruiting

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A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF

for Atrial Fibrillation

35 locations incl. Birmingham

Sponsor: Heart Rhythm Clinical and Research Solutions, LLC

Sex: All·Age: 18+

Code: NCT06335082·Enrolling By Invitation

A Clinical Study of the TSX Dental Implant System (Xpresso)

for Tooth Loss

2 locations incl. Columbus

Sponsor: ZimVie

Sex: All·Age: 18+

Code: NCT06571812·Recruiting

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ACP-204 in Adults With Alzheimer's Disease Psychosis Open Label Extension Study

for Alzheimer's Disease Psychosis

19 locations incl. Costa Mesa

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 55 - 95

Code: NCT06194799·Phase 3·Enrolling By Invitation

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

for Obstructive Sleep Apnea

4 locations incl. Tucson

Sponsor: California Pacific Medical Center Research Institute

Sex: All·Age: 55 - 85

Code: NCT05988385·Recruiting

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A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors

for Solid Tumor

17 locations incl. Duarte

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT06384807·Phase 1, Phase 2·Recruiting

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Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

156 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting

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Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

for Refractory Acute Myeloid Leukemia

Drug: Venetoclax

10 locations incl. San Diego

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 30

Code: NCT06177067·Phase 1·Recruiting

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A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

for Crohn's Disease

Drug: Ustekinumab

45 locations incl. Dothan

Sponsor: Takeda

Sex: All·Age: 18 - 70

Code: NCT06045754·Phase 4·Recruiting

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A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

38 locations incl. Little Rock

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06319820·Phase 3·Recruiting

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A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

for Lung Cancer, Non-small Cell

14 locations incl. Dothan

Sponsor: Krystal Biotech, Inc.

Sex: All·Age: 18+

Code: NCT06228326·Phase 1, Phase 2·Recruiting

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Evaluate the Effects of Long-term Use of Psychotropic Medications on Eye Movement Patterns With the Gaize Device

for ADHD

1 location in Philadelphia

Sponsor: Gaize

Sex: All·Age: 18 - 65

Code: NCT07389473·Recruiting

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The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for Intracranial Aneurysm

22 locations incl. Englewood

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 18 - 75

Code: NCT02998229·Recruiting

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A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)

for Niemann-Pick Diseases

5 locations incl. Chicago

Sponsor: Sanofi

Sex: All·Age: Up to 2

Code: NCT06192576·Recruiting

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Pivotal Trial of the Boomerang Catheter for pDVA

for Chronic Limb-Threatening Ischemia

19 locations incl. Sylmar

Sponsor: Aveera Medical, Inc.

Sex: All·Age: 18+

Code: NCT06311773·Enrolling By Invitation

Platform Clinical Study for Conquering Scleroderma

for Interstitial Lung Disease Due to Systemic Disease

34 locations incl. St Louis

Sponsor: Scleroderma Research Foundation, Inc.

Sex: All·Age: 18+

Code: NCT06195072·Phase 2·Recruiting

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Improving Care Transitions for Medicaid Insured Individuals With Co-occurring Serious Mental Illness

for Care Transitions

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06203509·Recruiting

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RemI for Post-Bariatric Surgery Weight Regain

for Obesity

2 locations incl. Chicago

Sponsor: Temple University

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06292936·Recruiting

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IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

61 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting

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A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

for Breast Neoplasms

46 locations incl. Chandler

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06312176·Phase 3·Recruiting

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Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

for Arthritis

7 locations incl. Carmel

Sponsor: Aptis Medical

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT05796908·Recruiting

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Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for Heart Failure and Impaired Kidney Function

Drug: Dapagliflozin

166 locations incl. Alexander City

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06307652·Phase 3·Recruiting

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iLookOut for Child Abuse: Micro-learning to Improve Knowledge Retention

for Child Abuse

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT04324619·Recruiting

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Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)

for Pelizaeus-Merzbacher Disease

3 locations incl. Atlanta

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: Male·Age: 2 - 17

Code: NCT06150716·Phase 1·Recruiting

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Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for Non-Small Cell Lung Cancer

Drug: Livmoniplimab

19 locations incl. La Jolla

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06236438·Phase 2, Phase 3·Recruiting

Apply to this trial