Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,677 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,674 clinical trials

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iLookOut Micro-learning to Improve Knowledge Retention

for Knowledge

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06273618·Recruiting

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A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

for Neoplasms

4 locations incl. New York

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18+

Code: NCT06311578·Phase 1·Recruiting

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A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for Oncology

17 locations incl. San Francisco

Sponsor: Nested Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06326411·Phase 1·Recruiting

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Intramedullary Calcium Sulfate Antibiotic Depot

for Open tíbia Fracture

10 locations incl. Los Angeles

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05766670·Phase 3·Recruiting

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Comparing Two Different Emotion Therapies for Autistic Youth and Young Adults

for Autism Spectrum Disorder

2 locations incl. Tuscaloosa

Sponsor: University of Pittsburgh

Sex: All·Age: 10 - 30

Code: NCT06158581·Recruiting

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[18F]FES PET/.CT in Uterine Cancer

for Uterine Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 18+

Code: NCT05916196·Phase 2·Recruiting

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Empagliflozin Treatment in Kidney Transplant Recipients

for Kidney Transplant

Drug: Empagliflozin

5 locations incl. Hines

Sponsor: VA Office of Research and Development

Sex: All·Age: 19+

Code: NCT06013865·Phase 4·Recruiting

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AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion

for Aortic Aneurysm, Abdominal

39 locations incl. Birmingham

Sponsor: Shape Memory Medical, Inc.

Sex: All·Age: 18+

Code: NCT06029660·Recruiting

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Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition

for Primary Myelofibrosis

Drug: Pacritinib

1 location in Philadelphia

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT06218628·Phase 1·Recruiting

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Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

for Acne

79 locations incl. Scottsdale

Sponsor: Sanofi Pasteur, a Sanofi Company

Sex: All·Age: 18 - 45

Code: NCT06316297·Phase 1, Phase 2·Recruiting

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Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients

for Cytomegalovirus Infections

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06066957·Phase 2·Recruiting

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Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

for Ovarian Cancer

17 locations incl. Duarte

Sponsor: Xencor, Inc.

Sex: All·Age: 15+

Code: NCT06276491·Phase 1·Recruiting

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iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for Pediatric PH

for Pulmonary Hypertension

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 8 - 18

Code: NCT05442671·Recruiting

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Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation

for Delirium

2 locations incl. Boston

Sponsor: Penn State University

Sex: All·Age: 70+

Code: NCT05915377·Recruiting

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A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

for Non Small Cell Lung Cancer

49 locations incl. Little Rock

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06312137·Phase 3·Recruiting

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Diabetic Foot Ulcer (DFU) Biofilm Infection and Recurrence

for Chronic Wounds

2 locations incl. Tucson

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT05172089·Recruiting

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Combined Thrombectomy for Distal MediUm Vessel Occlusion StroKe

for Ischemic Stroke

4 locations incl. Atlanta

Sponsor: Raul Nogueira

Sex: All·Age: 18+

Code: NCT05983757·Recruiting

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Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking

for Lung Carcinoma

1 location in Philadelphia

Sponsor: Ronald Myers

Sex: All·Age: 50 - 77·Accepts healthy volunteers

Code: NCT05679349·Recruiting

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A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection

for Cystic Fibrosis Lung

13 locations incl. Tucson

Sponsor: Respirion Pharmaceuticals Pty Ltd

Sex: All·Age: 12+

Code: NCT06016088·Phase 1, Phase 2·Recruiting

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Passive Calf Stretching Therapy in Peripheral Artery Disease

for Peripheral Artery Disease

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 40 - 85

Code: NCT06041880·Recruiting

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Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

for HIV-1-infection

10 locations incl. San Diego

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06071767·Phase 1, Phase 2·Recruiting

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MicroRNAs as Biomarkers for Obstructive Sleep Apnea

for Obstructive Sleep Apnea

2 locations incl. Columbus

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 75

Code: NCT06189755·Recruiting

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A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

for Heart Failure

Drug: Ziltivekimab

41 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT06200207·Phase 3·Recruiting

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Esophageal String Test Monitoring to Monitor Eosinophilic Esophagitis During Oral Immunotherapy

for Eosinophilic Esophagitis (EoE)

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 7 - 17

Code: NCT06389994·Recruiting

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Testing an Intergenerational Model of Suicide Risk in Mother-child Dyads

for Emotion Regulation

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT06463054·Recruiting

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Self-Management for Head and Neck Lymphedema and Fibrosis [PROMISE Trial]

for Lymphedema of the Head and Neck

2 locations incl. Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06125743·Recruiting

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A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

for Recurrent Langerhans Cell Histiocytosis

105 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 180 Days - 22

Code: NCT05828069·Phase 2·Recruiting

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A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

for Antineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV)

16 locations incl. Beverly Hills

Sponsor: Fate Therapeutics

Sex: All·Age: 12 - 70

Code: NCT06308978·Phase 1·Recruiting

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Promoting Shared Decision Making for Severe Aortic Stenosis

for Aortic Stenosis

8 locations incl. San Francisco

Sponsor: Massachusetts General Hospital

Sex: All·Age: 65 - 85

Code: NCT06171737·Enrolling By Invitation

A Study of Participants With Cerebral Adrenoleukodystrophy (CALD) Treated With Elivaldogene Autotemcel

for Cerebral Adrenoleukodystrophy (CALD)

3 locations incl. Boston

Sponsor: Genetix Biotherapeutics Inc.

Sex: Male·Age: All ages

Code: NCT06224413·Recruiting

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The Patient and Family Centered I-PASS LISTEN Study: Language, Inclusion, Safety, and Teamwork for Equity Now

for Communication

8 locations incl. Birmingham

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT05591066·Recruiting

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A Phase 1/2 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia (CARDINAL)

for Chronic Myeloid Leukemia, Chronic Phase

18 locations incl. Birmingham

Sponsor: Terns, Inc.

Sex: All·Age: 18+

Code: NCT06163430·Phase 1, Phase 2·Recruiting

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The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System

for Polycystic Ovary Syndrome

24 locations incl. Encino

Sponsor: May Health

Sex: Female·Age: 18 - 40

Code: NCT06206746·Recruiting

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Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

for Non-small Cell Lung Cancer

18 locations incl. Duarte

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06218914·Phase 1·Recruiting

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Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis

for Pulmonary Sarcoidosis

7 locations incl. Birmingham

Sponsor: Molecure S.A.

Sex: All·Age: 18+

Code: NCT06205121·Phase 2·Recruiting

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A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

for Neoplasms, Head and Neck

Drug: Dostarlimab

36 locations incl. Jonesboro

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06256588·Phase 3·Recruiting

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Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

41 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06297226·Phase 2·Recruiting

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Daily Goal Setting to Increase Everyday Physical Activity and Promote Cognitive Health in Midlife

for Physical Inactivity

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 30 - 70·Accepts healthy volunteers

Code: NCT05826379·Enrolling By Invitation

Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement

for Opioid Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05897788·Recruiting

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Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia

for Insomnia

3 locations incl. Denver

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT06281756·EARLY_Phase 1·Recruiting

Apply to this trial