Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,663 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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3,663 clinical trials

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Adult Trauma Centers RE-AIM at Gun Safety

for Firearm Injury

3 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06302452·Enrolling By Invitation

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohn Disease

43 locations incl. Fairhope

Sponsor: Abivax S.A.

Sex: All·Age: 18 - 75

Code: NCT06456593·Phase 2·Recruiting

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Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for Neuroblastoma

20 locations incl. Birmingham

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 30

Code: NCT06541262·Phase 1, Phase 2·Recruiting

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A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

for Age-related Macular Degeneration (AMD)

Drug: Cemdisiran

152 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 50 - 85

Code: NCT06541704·Phase 3·Recruiting

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A Study to Investigate the Safety and Efficacy of SAR446523 Injected Subcutaneously in Adult Participants With Relapsed/Refractory Myeloma

for Plasma Cell Myeloma Refractory

5 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06630806·Phase 1·Recruiting

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A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer

12 locations incl. La Jolla

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06644768·Phase 1, Phase 2·Recruiting

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The THOR IDE Study

for Peripheral Artery Disease

29 locations incl. St. Helena

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT05916950·Recruiting

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The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

for Metastatic Breast Cancer

73 locations incl. Chandler

Sponsor: American Society of Clinical Oncology

Sex: All·Age: 65+

Code: NCT06377852·Phase 3·Recruiting

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A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.

for Endometrial Cancer

Drug: Lifileucel

12 locations incl. Phoenix

Sponsor: Iovance Biotherapeutics, Inc.

Sex: Female·Age: 18 - 70

Code: NCT06481592·Phase 2·Recruiting

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Safety Study of SMOFlipid to Evaluate the Risk of Developing EFAD and/or PNAC in Pediatric and Adult Patients

for Malnutrition, Child

5 locations incl. Atlanta

Sponsor: Fresenius Kabi

Sex: All·Age: 1 Month - 17

Code: NCT06049680·Phase 4·Recruiting

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Apimostinel + Automated Neurocognitive Training for Depression

for Depression

1 location in Pittsburgh

Sponsor: Rebecca Price

Sex: All·Age: 18 - 60

Code: NCT06400121·Phase 2·Recruiting

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Bright Light Therapy for OSA

for Obstructive Sleep Apnea

1 location in Pittsburgh

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 65

Code: NCT05917119·Recruiting

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Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis

for Recurrent Acute Pancreatitis

5 locations incl. Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18 - 75

Code: NCT05771675·EARLY_Phase 1·Recruiting

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A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

for Sickle Cell Disease

14 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT06439082·Phase 3·Recruiting

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A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

for Healthy Volunteers, Pulmonary Arterial Hypertension

19 locations incl. Scottsdale

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06649110·Phase 1, Phase 2·Recruiting

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Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

for Classic Follicular Lymphoma

Drug: Mosunetuzumab

267 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06337318·Phase 3·Recruiting

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Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma

for Rib Fractures

1 location in Pittsburgh

Sponsor: Rebecca E Kotcher, MD

Sex: All·Age: 18+

Code: NCT06626334·Recruiting

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Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.

for Vasculitis

Drug: Rituximab

10 locations incl. Atlanta

Sponsor: Amgen

Sex: All·Age: 6 - 17

Code: NCT06321601·Phase 3·Recruiting

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A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for Basal Ganglia Germinoma

92 locations incl. Mobile

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT06368817·Phase 2·Recruiting

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Sacral Neuromodulation for Male Overactive Bladder (MOAB)

for Overactive Bladder

20 locations incl. Birmingham

Sponsor: Axonics, Inc.

Sex: Male·Age: 18+

Code: NCT06511141·Recruiting

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Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

for Amblyopia

58 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 8 - 12

Code: NCT06524882·Phase 3·Recruiting

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Dyadic Sleep Study

for Gastrointestinal Cancer

2 locations incl. Coral Gables

Sponsor: University of Miami

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06569693·Recruiting

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ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)

for Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome

8 locations incl. San Diego

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: Male·Age: 2 - 65

Code: NCT06430385·Phase 1, Phase 2·Recruiting

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Open-Label Extension Study of Setmelanotide

for Obesity Associated With Defects in Leptin-melanocortin Pathway

13 locations incl. Scottsdale

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 2+

Code: NCT06596135·Phase 3·Enrolling By Invitation

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for Carcinoma, Non-Small-Cell Lung

Drug: Intismeran autogene

48 locations incl. Gilbert

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06623422·Phase 3·Recruiting

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Characterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 Variants

for Williams Beuren Syndrome

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06930417·Recruiting

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Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

for Hypertensive Disorders of Pregnancy

16 locations incl. Birmingham

Sponsor: Ohio State University

Sex: Female·Age: 14 - 35

Code: NCT06468202·Phase 4·Recruiting

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A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

for Colorectal Neoplasms

Drug: Amivantamab

79 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06662786·Phase 3·Recruiting

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Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06401577·Recruiting

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Clinical Outcomes of Patients with LAL+ in At Least One Eye

for IOL, Cataract

1 location in Wilkes-Barre

Sponsor: Frank A. Bucci, Jr., M.D.

Sex: All·Age: All ages

Code: NCT06650358·Enrolling By Invitation

Enhancing Memory in CPT for PTSD

for Stress Disorders, Post-Traumatic

1 location in Philadelphia

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT06000475·Recruiting

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Criterion-learning Based Naming Treatment in Aphasia

for Aphasia

1 location in Elkins Park

Sponsor: Albert Einstein Healthcare Network

Sex: All·Age: 18 - 89

Code: NCT06364709·Enrolling By Invitation

A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

76 locations incl. Mesa

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting

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Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

for Arthritis, Psoriatic

44 locations incl. Avondale

Sponsor: MoonLake Immunotherapeutics AG

Sex: All·Age: 18+

Code: NCT06641089·Phase 3·Recruiting

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Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

for Liver Neoplasms

30 locations incl. Fullerton

Sponsor: HistoSonics, Inc.

Sex: All·Age: 22+

Code: NCT06486454·Recruiting

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Open-label Extension Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy

for Familial Partial Lipodystrophy

7 locations incl. Birmingham

Sponsor: Amryt Pharma

Sex: All·Age: 13+

Code: NCT06679270·Phase 3·Recruiting

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A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia

for Leukemia, Juvenile Myelomonocytic

Drug: Trametinib

19 locations incl. Phoenix

Sponsor: Therapeutic Advances in Childhood Leukemia Consortium

Sex: All·Age: 1 Month - 21

Code: NCT05849662·Phase 1, Phase 2·Recruiting

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Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations

for Solid Tumours

20 locations incl. Anchorage

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06581432·Phase 2·Recruiting

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QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

for HER2-positive Metastatic Breast Cancer

37 locations incl. San Francisco

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06551116·Recruiting

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A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults

for Episodic Migraine

71 locations incl. Birmingham

Sponsor: Ipsen

Sex: All·Age: 18 - 80

Code: NCT06625060·Phase 2·Recruiting

Apply to this trial