Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,661 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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3,663 clinical trials

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A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

for COVID-19 SARS-CoV-2 Infection

84 locations incl. Little Rock

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT06679140·Phase 3·Recruiting

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Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion

for Degenerative Disc Disease

6 locations incl. Irvine

Sponsor: Kuros Biosurgery AG

Sex: All·Age: 18+

Code: NCT04679844·Recruiting

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Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma

for Neuroblastoma

12 locations incl. Little Rock

Sponsor: Giselle Sholler

Sex: All·Age: 1 - 21

Code: NCT06540963·Phase 2·Recruiting

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The Social Determinants of Health Screening and Referral Project

for Preterm Birth

7 locations incl. Denver

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18+

Code: NCT06582147·Enrolling By Invitation

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

16 locations incl. Farmington

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18+

Code: NCT06667908·Phase 2·Recruiting

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Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.

for Venous Leg Ulcer

1 location in Monroeville

Sponsor: Tiger Biosciences, LLC.

Sex: All·Age: 21+

Code: NCT06826339·Phase 4·Recruiting

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A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for Recurrent Mycosis Fungoides

10 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07003100·Recruiting

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A Study to Document and to Further Describe Long-term Safety and Effectiveness of Palovarotene in Participants With Fibrodysplasia Ossificans Progressiva (FOP)

for Fibrodysplasia Ossificans Progressiva

2 locations incl. San Francisco

Sponsor: Ipsen

Sex: All·Age: 8+

Code: NCT06089616·Recruiting

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Vagal Stimulator to Reduce Nasogastric Tube Use

for Nasogastric Tube Intubation

1 location in Pittsburgh

Sponsor: Jacques E. Chelly

Sex: All·Age: 18+

Code: NCT06648759·Recruiting

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Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)

for Dilated Cardiomyopathy

1 location in Lancaster

Sponsor: Lancaster General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06688396·Recruiting

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Feasibility of Resting Intervals During Exercise Programs for Individuals With Knee Osteoarthritis

for Knee Osteoarthristis

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 45 - 79

Code: NCT06857123·Recruiting

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A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

for Psoriatic Arthritis

Drug: Upadacitinib

3 locations incl. Cleveland

Sponsor: CARE ARTHRITIS LTD.

Sex: All·Age: 18+

Code: NCT06454188·Phase 4·Recruiting

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Dose-Response to Resistance Exercise on Cardiovascular Health

for Cardiovascular Risk

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 40+

Code: NCT06619444·Recruiting

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OurSleepKit To Support CPAP Adherence

for Obstructive Sleep Apnea

2 locations incl. Boston

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18+

Code: NCT06621511·Recruiting

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A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

24 locations incl. Phoenix

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06679946·Phase 3·Enrolling By Invitation

Impact of Obicetrapib and Obicetrapib Plus Repatha on Lp(a) Levels

for Dyslipidemias

Drug: Obicetrapib

1 location in Philadelphia

Sponsor: NewAmsterdam Pharma

Sex: All·Age: 18 - 75

Code: NCT06496243·Phase 2·Recruiting

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A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

for HIV Infections

41 locations incl. Birmingham

Sponsor: ViiV Healthcare

Sex: All·Age: 12+

Code: NCT06694805·Phase 3·Recruiting

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Assessing Perceptions of ML Explanations by Medical Oncologists

for Oncology

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: All ages

Code: NCT06699615·Enrolling By Invitation

Meditation Effects on Discomfort, Pain InTerference, and AnxieTy After urEteroscopy

for Kidney Stone

2 locations incl. Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 12+·Accepts healthy volunteers

Code: NCT06783946·Enrolling By Invitation

A Study of RSLV-132 in Females With Sjögren's Disease

for Primary Sjögren Syndrome

24 locations incl. Chula Vista

Sponsor: Resolve Therapeutics

Sex: Female·Age: 18 - 75

Code: NCT06440525·Phase 2·Recruiting

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Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

for Cystic Fibrosis

31 locations incl. Birmingham

Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center

Sex: All·Age: 3 - 18

Code: NCT06654752·Recruiting

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Implementation of Red Blood Cell Transfusion Recommendations in the Pediatric Intensive Care Unit

for Red Blood Cell Transfusions

2 locations incl. Palo Alto

Sponsor: Stanford University

Sex: All·Age: All ages

Code: NCT07108374·Enrolling By Invitation

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

for Pleural Biphasic Mesothelioma

132 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05647265·Phase 2·Recruiting

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CoMind Early Feasibility Study

for Intracranial Pressure

14 locations incl. Sacramento

Sponsor: CoMind Technologies Limited

Sex: All·Age: 18+

Code: NCT06368648·Recruiting

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Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

for Castration-Resistant Prostate Carcinoma

174 locations incl. Fayetteville

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT06470243·Phase 3·Recruiting

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Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

for B-cell Non-Hodgkin Lymphoma

23 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06526793·Phase 2·Recruiting

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC

for Non-squamous Non-small Cell Lung Cancer

Drug: Rilvegostomig

77 locations incl. Mobile

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06627647·Phase 3·Recruiting

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A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

for B-cell Malignancy

18 locations incl. Phoenix

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06634589·Phase 1, Phase 2·Recruiting

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Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

for Normal Pressure Hydrocephalus

28 locations incl. Los Angeles

Sponsor: CereVasc Inc

Sex: All·Age: 60+

Code: NCT06498960·Recruiting

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Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

for Prostate Cancer

7 locations incl. San Francisco

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT06613100·Phase 1·Recruiting

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Evaluating Intact Fish Skin Graft and Standard of Care Versus Standard of Care Alone in Nonhealing Venous Leg Ulcers

for Venous Leg Ulcer (VLU)

1 location in Monroeville

Sponsor: Kerecis Ltd.

Sex: All·Age: 18+

Code: NCT06693570·Phase 4·Recruiting

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Assessing the Impact of VR-Based Observational Mindfulness Meditation on Stress Reduction in Adults

for Stress

1 location in Erie

Sponsor: Penn State University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06704282·Not Yet Recruiting

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for Alzheimers Disease

12 locations incl. Birmingham

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05552157·Phase 2, Phase 3·Recruiting

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Acellular Dermal Matrix Investigation in Breast Reconstruction

for Breast Reconstruction

13 locations incl. Little Rock

Sponsor: RTI Surgical

Sex: Female·Age: 22+·Accepts healthy volunteers

Code: NCT06456554·Recruiting

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A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

for Gastroesophageal-junction Cancer

29 locations incl. Anaheim

Sponsor: Shanghai Henlius Biotech

Sex: All·Age: 18+

Code: NCT06532006·Phase 3·Recruiting

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A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for Alzheimers Disease

12 locations incl. Birmingham

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06647498·Phase 2, Phase 3·Recruiting

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A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

for Noonan Syndrome

Drug: Vosoritide

22 locations incl. Los Angeles

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06668805·Phase 2·Recruiting

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A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

for Eosinophilic Esophagitis (EoE)

54 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 1+

Code: NCT06693531·Recruiting

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A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

61 locations incl. Avondale

Sponsor: UCB Biopharma SRL

Sex: All·Age: 16+

Code: NCT06617325·Phase 3·Recruiting

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A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

for Chronic Graft-Versus-Host Disease (cGVHD)

26 locations incl. Duarte

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06619561·Phase 2·Recruiting

Apply to this trial