Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,661 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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3,663 clinical trials

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Remote Sputum Collection in Cystic Fibrosis

for Cystic Fibrosis

3 locations incl. Denver

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06950892·Recruiting

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A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

for Acute Myeloid Leukemia

Drug: Venetoclax

24 locations incl. Los Angeles

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06456463·Phase 2·Recruiting

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A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for Colorectal Cancer

44 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06562543·Phase 4·Recruiting

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A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

for Breast Cancer

17 locations incl. Prescott

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06695845·Phase 2·Recruiting

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SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

for Melanoma, Cutaneous Malignant

40 locations incl. Phoenix

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT06743126·Phase 3·Recruiting

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Response to Emerging Antimicrobial Resistance With Containment Microbiota Therapy (REACT)

for Multi-Drug Resistant Organism Colonization

4 locations incl. Atlanta

Sponsor: Emory University

Sex: All·Age: 18+

Code: NCT06321536·Phase 2·Recruiting

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GLP-1R Agonist Treatment for Opioid Use Disorder

for Opioid Use Disorder

3 locations incl. Baltimore

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06548490·Phase 2·Recruiting

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Nitrous Oxide Neuroimaging

for Anesthesia

1 location in Pittsburgh

Sponsor: Keith M Vogt

Sex: All·Age: 18 - 59·Accepts healthy volunteers

Code: NCT06702631·EARLY_Phase 1·Recruiting

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Family Foundations for Special Education Trial

for Mental Health

1 location in Philadelphia

Sponsor: Penn State University

Sex: All·Age: 18+

Code: NCT07400497·Recruiting

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Topical Anti-Androgens in Pilonidal Sinus Disease

for Pilonidal Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06286397·Phase 2·Recruiting

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AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)

for Phenylketonurias

5 locations incl. Orange

Sponsor: NGGT INC.

Sex: All·Age: 18 - 55

Code: NCT06332807·Phase 1, Phase 2·Recruiting

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An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

11 locations incl. Los Angeles

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06589596·Phase 1·Recruiting

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A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

for Type 2 Diabetes

Drug: Dulaglutide

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 10 - 17

Code: NCT06739122·Phase 3·Recruiting

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A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

for NSCLC (Advanced Non-small Cell Lung Cancer)

23 locations incl. Phoenix

Sponsor: BlossomHill Therapeutics

Sex: All·Age: 18+

Code: NCT06706076·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

for Arthritis, Psoriatic

23 locations incl. Glendale

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06807424·Phase 3·Recruiting

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A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder

for Social Anxiety Disorder

9 locations incl. Sherman Oaks

Sponsor: VistaGen Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06809179·Phase 2·Recruiting

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Study of Healthy Donor FMT (hdFMT) and Pembrolizumab in Relapsed/Refractory (R/R) PD-L1 Positive NSCLC

for Non Small Cell Lung Cancer

1 location in Pittsburgh

Sponsor: Diwakar Davar

Sex: All·Age: 18+

Code: NCT05669846·Phase 2·Recruiting

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Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization

for Neurogenic Detrusor Overactivity

4 locations incl. Downey

Sponsor: EG 427

Sex: All·Age: 18 - 75

Code: NCT06596291·Phase 1, Phase 2·Recruiting

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Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL

for CTCL/ Mycosis Fungoides

17 locations incl. Phoenix

Sponsor: Soligenix

Sex: All·Age: 18+

Code: NCT06470451·Phase 3·Recruiting

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BHB & CAR-T for Lymphomas

for Large B-cell Lymphoma

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06610344·Recruiting

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A Phase 1 Study of LNCB74 in Advanced Solid Tumors

for Ovarian Cancer

14 locations incl. Newport Beach

Sponsor: NextCure, Inc.

Sex: All·Age: 18+

Code: NCT06774963·Phase 1·Recruiting

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The Apollo Device in Systemic Sclerosis for the Management of fatiguE, Raynaud Phenomenon and qualiTy of Life

for Systemic Sclerosis (SSc)

4 locations incl. New Orleans

Sponsor: Robyn T. Domsic, MD, MPH

Sex: All·Age: 18+

Code: NCT06675344·Recruiting

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Variability in Analgesic Response to Ibuprofen

for Impacted Third Molar Tooth

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06539741·Recruiting

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Utility of Random Biopsies in Patients With Inflammatory Bowel Disease

for Inflammatory Bowel Diseases

20 locations incl. Birmingham

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06560021·Enrolling By Invitation

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

21 locations incl. Chandler

Sponsor: Loxo Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06588478·Phase 2·Recruiting

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IMmunotherapy: Prospective Assessment of Cannabis Treatment in Cancer

for Cancer

2 locations incl. Portland

Sponsor: State University of New York at Buffalo

Sex: All·Age: 21+

Code: NCT06206941·Recruiting

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Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma

for Cutaneous Squamous Cell Carcinoma (CSCC)

Drug: Cemiplimab

45 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06585410·Phase 3·Recruiting

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The Collaborative Care PrTNER Study

for HIV

2 locations incl. Baltimore

Sponsor: Children's Hospital of Philadelphia

Sex: Male·Age: 15 - 29·Accepts healthy volunteers

Code: NCT06585631·Recruiting

Apply to this trial

Validation of Nanosensor Oxygen Measurement

for MItochondrial Myopathies

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06819683·Phase 1·Recruiting

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Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer

for Cancer

1 location in Pittsburgh

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: Female·Age: 20 - 89

Code: NCT06858449·Recruiting

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Leveraging Lung Cancer Screening to Optimize Screening Outcomes and COPD Management: COPD in LCS Registry

for COPD

1 location in Philadelphia

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

Sex: All·Age: 50 - 80

Code: NCT06974981·Recruiting

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Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation

for Metastatic Prostate Carcinoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Male·Age: 18+

Code: NCT05487846·Recruiting

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Oropharyngeal Candidiasis (OPC) and S-ECC

for Candida Infection

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 9 Months - 24 Months·Accepts healthy volunteers

Code: NCT05761197·Recruiting

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Utility and Effectiveness of Polygenic Risk Scoring (PRS) for Coronary Artery Disease (CAD)

for Coronary Artery Disease

2 locations incl. Rochester

Sponsor: MyOme

Sex: All·Age: 40 - 70

Code: NCT06542432·Enrolling By Invitation

How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care.

for Pneumonia

1 location in Bloomsburg

Sponsor: Geisinger Clinic

Sex: All·Age: 65 - 100

Code: NCT06495021·Recruiting

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A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

for Treatment Resistant Depression

34 locations incl. Tucson

Sponsor: atai Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06524830·Phase 2·Recruiting

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A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

for Advanced Hepatocellular Carcinoma

16 locations incl. Phoenix

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06600321·Phase 1·Recruiting

Apply to this trial

Clinical Trial to Treat Stage IV Cancer Patients

for Soft Tissue Cancer

1 location in Hershey

Sponsor: Moonshot Antibodies

Sex: All·Age: 18+

Code: NCT06674538·Phase 1·Enrolling By Invitation

A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

for Staphylococcus Aureus

43 locations incl. Huntsville

Sponsor: AstraZeneca

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT06749457·Phase 1, Phase 2·Recruiting

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Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors

for Malignant Mesothelioma

6 locations incl. Denver

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 18+

Code: NCT06566079·Phase 1·Recruiting

Apply to this trial