Oropharyngeal Candidiasis (OPC) and S-ECC

Part of paid clinical trials in Philadelphia, Pennsylvania.

Sponsor
Temple University
Study ID
NCT05761197
Status
Recruiting
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Conditions

  • Candida Infection
  • Early Childhood Caries
  • Oral Thrush

Eligibility Criteria

Sex
ALL
Age
9 Months - 24 Months
Healthy Volunteers
Accepted

Study Details

The overall objective of this study is to investigate the association of early Candida infection (known as oral thrush or oropharyngeal candidiasis, OPC) in children during the first year of life with the onset and severity of severe early childhood caries (S-ECC).

Key Dates

Start date
Jan 1, 2025
Status verified
Jul 2025
Primary completion
Aug 31, 2028
Completion
Aug 31, 2028

Study Design

Enrollment
70 participants (estimated)

Arms

  • Arm: Children with history of OPC
    Individuals in the non-OPC cohort will be age and sex-matched to individuals in the OPC cohort.
  • Arm: Children without history of OPC
    Individuals in the OPC cohort will be age and sex-matched to individuals in the non-OPC cohort.

Primary Outcome Measure

To explore the association between OPC and S-ECC onset and severity [ Time Frame: 24 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Temple UniversityPhiladelphiaPennsylvania19140
Yuan Liu, DDS, MS, PhD
[email protected]
215-707-8029

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By research site
Temple University· Philadelphia, PA

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