Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,661 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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3,661 clinical trials

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Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy

for Pancreatic Adenocarcinoma Metastatic

Drug: Ipilimumab

2 locations incl. Boston

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06747845·Phase 2·Recruiting

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Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

7 locations incl. Scottsdale

Sponsor: Tagworks Pharmaceuticals BV

Sex: All·Age: 18+

Code: NCT06959706·Phase 1·Recruiting

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Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis

for Myasthaenia Gravis

23 locations incl. Tucson

Sponsor: Cartesian Therapeutics

Sex: All·Age: 18+

Code: NCT06799247·Phase 3·Recruiting

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Social Media Intervention for Online Victimized Youth

for Depression

2 locations incl. Philadelphia

Sponsor: University of Pittsburgh

Sex: All·Age: 12 - 18

Code: NCT06835985·Enrolling By Invitation

CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

for SLE

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 12 - 29

Code: NCT06839976·Phase 1, Phase 2·Recruiting

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Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

for NSCLC (Non-small Cell Lung Cancer)

Drug: daraxonrasib

39 locations incl. Birmingham

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06881784·Phase 3·Recruiting

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Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

for Hepatocellular Carcinoma

Drug: Rilvegostomig

35 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06921785·Phase 3·Recruiting

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Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

for Sleep Disturbance

2 locations incl. Philadelphia

Sponsor: University of Pittsburgh

Sex: All·Age: 12 - 18

Code: NCT06963463·Recruiting

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Intra-tumoral (IT) Injection of vvDD-hIL2-2-RG-1 for Metastatic Gastrointestinal and Peritoneal Tumors

for Gastric Neoplasms

1 location in Pittsburgh

Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sex: All·Age: 18 - 69

Code: NCT07001592·Phase 1·Recruiting

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Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2

for Intracerebral Hemorrhage

48 locations incl. Birmingham

Sponsor: Joseph Broderick, MD

Sex: All·Age: 18 - 80

Code: NCT07227246·Phase 3·Recruiting

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WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

for Idiopathic Pulmonary Fibrosis

26 locations incl. Birmingham

Sponsor: Mediar Therapeutics

Sex: All·Age: 40+

Code: NCT06967805·Phase 2·Recruiting

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Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma

for Glioblastoma

2 locations incl. Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06613841·EARLY_Phase 1·Recruiting

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Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

for Cystic Fibrosis

18 locations incl. Birmingham

Sponsor: Boston Children's Hospital

Sex: All·Age: 6+

Code: NCT06683092·Recruiting

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A Study of Lorigerlimab in Participants With Advanced Solid Tumors

for Platinum-resistant Ovarian Cancer

7 locations incl. Los Angeles

Sponsor: MacroGenics

Sex: Female·Age: 18+

Code: NCT06730347·Phase 2·Recruiting

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Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass

for Pulmonary Hypertension

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07132788·Recruiting

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A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

for Muscular Diseases

13 locations incl. Los Angeles

Sponsor: Arcellx, Inc.

Sex: All·Age: 18+

Code: NCT06626919·Phase 1·Recruiting

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Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma

for Neuroblastoma

6 locations incl. Hartford

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: Up to 17

Code: NCT06831552·Recruiting

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Brain Activity Changes After Cognitive Behavioral Therapy for Anxiety in Autistic Youth From High-Need Communities

for Autism Spectrum Disorder

2 locations incl. Montclair

Sponsor: Montclair State University

Sex: All·Age: 8 - 14

Code: NCT06904508·Recruiting

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Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

for Hematuria - Cause Not Known

15 locations incl. Homewood

Sponsor: Pacific Edge Limited

Sex: All·Age: 18 - 88

Code: NCT06394869·Recruiting

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Adjuvant Concurrent Immunotherapy and Radiotherapy for the Treatment of Bladder Cancer

for Urothelial Carcinoma Bladder

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06586255·Phase 1·Recruiting

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Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

for Generalized Anxiety Disorder (GAD)

49 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT06846320·Phase 2·Recruiting

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Anti-CD7 CAR-T Cells in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia or Lymphoma

for T-Cell Acute Lymphoblastic Leukemia/Lymphoma

1 location in Philadelphia

Sponsor: Stephan Grupp MD PhD

Sex: All·Age: 0 - 29

Code: NCT06934382·Phase 1·Recruiting

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A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

for Lymphoma

Drug: Glofitamab

16 locations incl. La Jolla

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06624085·Phase 1·Recruiting

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Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)

for Adolescent Drinking

2 locations incl. Commerce

Sponsor: RAND

Sex: All·Age: 12 - 19·Accepts healthy volunteers

Code: NCT06699251·Recruiting

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Lead-212 PSV359 Therapy for Patients With Solid Tumors

for Pancreatic Ductal Adenocarcinoma

8 locations incl. Miami

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT06710756·Phase 1, Phase 2·Recruiting

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A Study to Assess the Safety and Risk of Hypersensitivity Reactions of Sulbactam-durlobactam in Adults With Acinetobacter Baumannii-calcoaceticus (ABC) Complex Infection

for Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC)

10 locations incl. Gainesville

Sponsor: Innoviva Specialty Therapeutics

Sex: All·Age: 18+

Code: NCT06746883·Recruiting

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Helping Adults With Type 2 Diabetes Use Their Health Data for Healthy Diabetes Self-Management

for Type 2 Diabetes Mellitus (T2DM)

1 location in Pittsburgh

Sponsor: Ann-Marie Rosland

Sex: All·Age: 25 - 75

Code: NCT06848361·Enrolling By Invitation

Comparative Study of Three Collagen Membranes: 1 Non-cross-linked and 2 Cross-linked

for Bone Regeneration

1 location in Pittsburgh

Sponsor: Andrea Ravida

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06944639·Enrolling By Invitation

T1D Pregnancy & Me

for Diabetes Mellitus, Type 1

10 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: Female·Age: 18+

Code: NCT06959316·Recruiting

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A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

for Carcinoma, Non-Small-Cell Lung

Drug: Adagrasib

54 locations incl. Birmingham

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06875310·Phase 3·Recruiting

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Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

for Severe Hypertriglyceridemia

Drug: Plozasiran

16 locations incl. Los Angeles

Sponsor: Arrowhead Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06880770·Phase 3·Recruiting

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MMA Embolization for Refractory Chronic Migraine

for Migraine Disorders

9 locations incl. Phoenix

Sponsor: Cerenovus, Part of DePuy Synthes Products, Inc.

Sex: All·Age: 18 - 65

Code: NCT06735833·Recruiting

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Intratumoral Lidocaine Injection Before Oropharyngeal Cancer Surgery

for Oropharyngeal Squamous Cell Carcinoma (OPSCCA)

1 location in Philadelphia

Sponsor: Ryan Carey

Sex: All·Age: 18+

Code: NCT06747390·Phase 1·Recruiting

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Pivotal Study for the Cardiac Performance System (CPS)

for Cardiovascular Diseases

10 locations incl. Huntsville

Sponsor: Sensydia Corporation

Sex: All·Age: 18+

Code: NCT06870591·Recruiting

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Uterine Preservation in the Management of Placenta Accreta Spectrum Disorders

for Placenta Accreta Spectrum

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: 18+

Code: NCT06512181·Recruiting

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Use of tAN® in Alcohol Withdrawal Management

for Alcohol Withdrawal

1 location in Wernersville

Sponsor: Erin Deneke

Sex: All·Age: 18 - 65

Code: NCT06771037·Recruiting

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Healthy Volunteers Study

for Ovarian Cancer

1 location in Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: Female·Age: 30 - 50·Accepts healthy volunteers

Code: NCT06962059·Recruiting

Apply to this trial

Fusion or Cognitive Ultrasound-guided Biopsy to Detect Prostate Cancer

for Prostate Cancer

3 locations incl. Burlington

Sponsor: Albany Medical College

Sex: Male·Age: 18+

Code: NCT06517901·Recruiting

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Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

for Metastatic Microsatellite Stable Colorectal Carcinoma

8 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06654037·Phase 1·Recruiting

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Cigarillo Public Education Messaging for Black Young Adults

for Cigarillo Smoking

2 locations incl. Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 30

Code: NCT06863168·Recruiting

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