Healthy Volunteers Study

Part of paid clinical trials in Philadelphia, Pennsylvania.

Sponsor
Abramson Cancer Center at Penn Medicine
Study ID
NCT06962059
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
FEMALE
Age
30 Years - 50 Years
Healthy Volunteers
Accepted

Interventions

  • Self-Administered Sample Collection — OTHER
    Participants will collect vaginal swabs and a stool sample.

Study Details

The purpose of this study is to examine the role of the bacterial environments and metabolites in the early detection and prediction of ovarian cancer development. Vaginal swabs and stool samples will be collected from healthy volunteers, or those without a known ovarian cancer diagnosis or genetic ovarian cancer risk. These samples will be compared to samples from participants with increased cancer risk and ovarian cancer diagnoses.

Key Dates

Start date
Apr 21, 2025
Status verified
Feb 2026
Primary completion
Jan 15, 2027
Completion
May 25, 2027

Study Design

Enrollment
50 participants (estimated)

Arms

  • Arm: Healthy Volunteer
    Females 30 or older who do not have a genetic predisposition to ovarian cancer, are unaffected by cancer, and have not had bilateral oophorectomy.

Primary Outcome Measure

Microbiome Involvement [ Time Frame: One-time sample donation of vaginal swabs collected at the time of the patient's appointment. A subsequent stool sample will be provided within a week of the vaginal swab. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Abramson Cancer Center of the University of PennsylvaniaPhiladelphiaPennsylvania19104
Susan Domchek, MD
[email protected]
855-216-0098
Susan Domchek, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Philadelphia, PA

By condition
Ovarian cancer
By specialty
OncologyGynecologic oncologyWomen's health
By research site
Abramson Cancer Center of the University of Pennsylvania· Philadelphia, PA

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