Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

3,656 clinical trials

↓ Download CSV

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for Parkinson's Disease

Drug: Prasinezumab

42 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 85

Code: NCT07174310·Phase 3·Recruiting

Apply to this trial

A Study of KT-621 Administered Orally to Participants With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

20 locations incl. Birmingham

Sponsor: Kymera Therapeutics, Inc.

Sex: All·Age: 12 - 75

Code: NCT07217015·Phase 2·Recruiting

Apply to this trial

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

for Epileptic Encephalopathy

6 locations incl. Orange

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 2 - 12

Code: NCT07227857·Phase 1, Phase 2·Recruiting

Apply to this trial

Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)

for Cervical Carcinoma

18 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 25+·Accepts healthy volunteers

Code: NCT07281430·Recruiting

Apply to this trial

A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)

for Bipolar Disorder

Drug: Brenipatide

20 locations incl. Orange

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07286175·Phase 2·Recruiting

Apply to this trial

Tongue-out Radiation Therapy (TORT) for the Mitigation of Radiotherapy-related Toxicities in Patients With Head and Neck Cancer

for Head and Neck Carcinoma

1 location in Pittsburgh

Sponsor: Yvonne Mowery

Sex: All·Age: 18+

Code: NCT07227792·Recruiting

Apply to this trial

Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)

for Fragile X Syndrome

15 locations incl. Phoenix

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: Male·Age: 13 - 45

Code: NCT07209462·Phase 2·Recruiting

Apply to this trial

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for Epithelial Ovarian Cancer

64 locations incl. Birmingham

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06890338·Phase 2·Recruiting

Apply to this trial

Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

for Macular Telangiectasia Type 2 (MacTel)

23 locations incl. La Jolla

Sponsor: Neurotech Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06971939·Phase 4·Recruiting

Apply to this trial

Neurofeedback to Treat Depression - 2

for Major Depressive Disorder (MDD)

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 65

Code: NCT07159061·Recruiting

Apply to this trial

Sanctuary Farm Prescription in Adolescents

for Obesity &Amp

3 locations incl. Wilmington

Sponsor: Nemours Children's Clinic

Sex: All·Age: 12 - 17

Code: NCT07218588·Recruiting

Apply to this trial

Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

for Carcinoid Syndrome

17 locations incl. Gilbert

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07087054·Phase 3·Recruiting

Apply to this trial

Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)

for Autosomal Dominant Polycystic Kidney Disease (ADPKD)

26 locations incl. Alabaster

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 65

Code: NCT07161037·Phase 2·Recruiting

Apply to this trial

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

for Left Ventricular Systolic Dysfunction

Drug: Finerenone

22 locations incl. Aurora

Sponsor: Bayer

Sex: All·Age: 6 Months - 17

Code: NCT07188805·Phase 3·Recruiting

Apply to this trial

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

for Advanced or Metastatic Solid Tumors

15 locations incl. Santa Monica

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07205718·Phase 1, Phase 2·Recruiting

Apply to this trial

Opdualag vs. Cemiplimab/Fianlimab in Relation to the Immunological Response in Tumor and Peripheral Blood in Unresectable or Metastatic Melanoma

for Locally Advanced Melanoma

Drug: Cemiplimab

1 location in Pittsburgh

Sponsor: John Kirkwood

Sex: All·Age: 18+

Code: NCT07223411·Recruiting

Apply to this trial

Stories to Prevent (StoP) HPV Cancers

for Human Papillomavirus Vaccination

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06808776·Recruiting

Apply to this trial

A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

for Colorectal Cancer

Drug: Bevacizumab

11 locations incl. Phoenix

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT06948448·Phase 2·Recruiting

Apply to this trial

Gene Therapy for HER-Positive Cancer (SENTRY-HER2)

for HER2 Expressing Solid Tumors

6 locations incl. Los Angeles

Sponsor: Vironexis Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT07192432·Phase 1, Phase 2·Recruiting

Apply to this trial

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

for Metastatic Colorectal Cancer (CRC)

Drug: Bevacizumab

58 locations incl. Goodyear

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT07228832·Phase 3·Recruiting

Apply to this trial

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

for Advanced Hepatocellular Carcinoma

Drug: Cabozantinib

4 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06811116·Phase 1, Phase 2·Recruiting

Apply to this trial

This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment

for Atopic Dermatitis

43 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 12+

Code: NCT07290803·Recruiting

Apply to this trial

Monitoring Eating Across Locations (MEAL) - Timing, Intake, and Mealtime Evaluation (TIME)

for Pediatric Obesity

1 location in State College

Sponsor: Penn State University

Sex: All·Age: 6 - 9·Accepts healthy volunteers

Code: NCT07095166·Recruiting

Apply to this trial

Ketone and Hawthorn Extract Supplementation in Congestive Heart Failure

for Congestive Heart Failure(CHF)

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07166965·Enrolling By Invitation

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.

for Esophageal Cancer

14 locations incl. Cerritos

Sponsor: SOFIE

Sex: All·Age: 18+

Code: NCT07217704·Phase 3·Recruiting

Apply to this trial

Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions

for Prescribing Decisions

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06605807·Recruiting

Apply to this trial

A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

for Idiopathic Pulmonary Fibrosis

Drug: BI 765423

15 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07036523·Phase 2·Recruiting

Apply to this trial

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

for Ovarian Cancer

23 locations incl. La Jolla

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT07059845·Phase 2·Recruiting

Apply to this trial

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

for Bladder Cancer

10 locations incl. Los Angeles

Sponsor: EvolveImmune United, Inc

Sex: All·Age: 18+

Code: NCT07217171·Phase 1·Recruiting

Apply to this trial

A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Psoriatic Arthritis

for Arthritis, Psoriatic

16 locations incl. Avondale

Sponsor: MoonLake Immunotherapeutics AG

Sex: All·Age: 18+

Code: NCT07223138·Phase 3·Enrolling By Invitation

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for Ovarian Cancer

Drug: INCB123667

42 locations incl. Mobile

Sponsor: Incyte Corporation

Sex: Female·Age: 18 - 99

Code: NCT07023627·Phase 2·Recruiting

Apply to this trial

SpO2 Accuracy in Children

for Hypoxemia

1 location in Philadelphia

Sponsor: Nihon Kohden

Sex: All·Age: 0 Days - 12·Accepts healthy volunteers

Code: NCT07168798·Enrolling By Invitation

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

for Alzheimers Disease

Drug: Trontinemab

33 locations incl. Phoenix

Sponsor: Hoffmann-La Roche

Sex: All·Age: 50 - 90

Code: NCT07170150·Phase 3·Recruiting

Apply to this trial

Transformative Research in Diabetic Nephropathy 2.0

for Diabetic Nephropathies

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07444203·Recruiting

Apply to this trial

A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

for Hyperlipidemia

35 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 64

Code: NCT07216482·Phase 3·Recruiting

Apply to this trial

TMS for iEEG Monitoring Recordings

for EEG

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 75

Code: NCT07518745·Enrolling By Invitation

Impact of Anatomy-Based Cochlear Implant Programming on Early Performance

for Hearing Loss, Unilateral

6 locations incl. Iowa City

Sponsor: Med-El Corporation

Sex: All·Age: 18+

Code: NCT06734039·Enrolling By Invitation

Phase 2 Study of ADX-038 in Participants With Geographic Atrophy

for Geographic Atrophy Secondary to Age-related Macular Degeneration

17 locations incl. Gilbert

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 60+

Code: NCT06990269·Phase 2·Recruiting

Apply to this trial

A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

for Eosinophilic Esophagitis (EoE)

Drug: Dupilumab

10 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 6 Months - 6

Code: NCT07112378·Phase 3·Recruiting

Apply to this trial

Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial

for Acute Respiratory Distress Syndrome (ARDS)

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 Weeks - 17

Code: NCT07123961·Phase 2·Recruiting

Apply to this trial