Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,656 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,656 clinical trials

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Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital

for COPD

3 locations incl. Des Moines

Sponsor: Fisher and Paykel Healthcare

Sex: All·Age: 22+

Code: NCT07222410·Recruiting

Apply to this trial

Individual Differences in Gait and Osteoarthritis Pain

for Knee Osteoarthritis (OA)

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 45 - 80

Code: NCT07308873·Recruiting

Apply to this trial

Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis

for Stroke

1 location in Pittsburgh

Sponsor: Marco Capogrosso

Sex: All·Age: 22 - 70

Code: NCT07153536·Recruiting

Apply to this trial

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for Major Depressive Disorder

32 locations incl. Phoenix

Sponsor: Syndeio Biosciences, Inc

Sex: All·Age: 18 - 64

Code: NCT07115329·Phase 2·Recruiting

Apply to this trial

Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder

for GRIN-related Neurodevelopmental Disorder

17 locations incl. Los Angeles

Sponsor: GRIN Therapeutics, Inc.

Sex: All·Age: 1 Month - 18

Code: NCT07224581·Phase 3·Recruiting

Apply to this trial

Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma

for Open Angle Glaucoma

1 location in Philadelphia

Sponsor: Jonathon Myers

Sex: All·Age: 18+

Code: NCT07228221·Phase 4·Recruiting

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Heated Versus Aerosol-based Laparoscopic Chemotherapy for Cancer That Has Spread to the Peritoneum (Abdominal Lining)

for Peritoneal (Metastatic) Cancer

1 location in Pittsburgh

Sponsor: Patrick Wagner, MD, FACS

Sex: All·Age: 18 - 80

Code: NCT07282834·Phase 2·Recruiting

Apply to this trial

Spinal Dural Arteriovenous Fistula International Data and Outcomes Registry

for Spinal Dural Arteriovenous Fistula

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: All ages

Code: NCT07574645·Recruiting

Apply to this trial

External Drainage of Thoracic Duct Lymph to Reduce Inflammatory Cytokines in Septic Shock Patients

for Sepsis

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 80

Code: NCT04855786·Recruiting

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Study of ONC206 (JZP3507) in Advanced Pheochromocytoma and Paraganglioma

for Advanced Pheochromocytoma and Paraganglioma

9 locations incl. Los Angeles

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07282587·Phase 2·Recruiting

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A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers.

for Diabetic Foot Ulcer

1 location in Philidelphia

Sponsor: BioLab Holdings

Sex: All·Age: 18+

Code: NCT07364630·Phase 4·Recruiting

Apply to this trial

Bromocriptine for Patients With Schizophrenia and Prediabetes

for Schizophrenia

1 location in Pittsburgh

Sponsor: VA Pittsburgh Healthcare System

Sex: All·Age: 18+

Code: NCT03575000·Phase 4·Not Yet Recruiting

Adapting the Penny Chatbot for Perinatal OUD Patients: COPILOT

for Perinatal Opioid Use Disorder

2 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: Female·Age: All ages

Code: NCT06969261·Recruiting

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Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery

for Breast Cancer

4 locations incl. Bethesda

Sponsor: University Hospital, Basel, Switzerland

Sex: All·Age: 18+

Code: NCT07140172·Recruiting

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The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery

for Ventral Hernia

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18 - 75

Code: NCT07145099·Not Yet Recruiting

Supraglottic Airway for Resuscitation Trial

for Neonatal Resuscitation

30 locations incl. Birmingham

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 Days+

Code: NCT07150923·Recruiting

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Pilot Study Exploring the Feasibility, Acceptability, and Impact of Medically Tailored Meals on Post-Discharge Recovery in Patients With Heart Failure

for Heart Failure

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07251894·Enrolling By Invitation

Restorative Neurophysiology: Backing up and Restoring the Brain (BandR)

for Adults With Variability in Their Mood

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07252011·Recruiting

Apply to this trial

Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar

for Burns

2 locations incl. Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06857435·Not Yet Recruiting

Autologous Point-of-Care Adipose Therapy: Recent Injury

for Burns

2 locations incl. Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06857448·Not Yet Recruiting

CaRi-Heart Assessment of Risk and Evaluation of Inflammation in Coronary CT Angiography (CARE-CCTA)

for Coronary Artery Disease

18 locations incl. Bay City

Sponsor: Corazon Medical PC

Sex: All·Age: All ages

Code: NCT07220304·Not Yet Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

for Untreated, Unresectable, or Metastatic Colorectal Cancer

Drug: Bevacizumab

49 locations incl. Tucson

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07221357·Phase 2, Phase 3·Recruiting

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Evaluation of Gadolinium Based Contrast Agents for Portable MR Imaging Systems

for Intra-axial Tumors

4 locations incl. Amherst

Sponsor: Hyperfine

Sex: All·Age: 18+

Code: NCT07296263·Enrolling By Invitation

Better Social, Emotional Communication, Healthy Relationship and ASD Accommodation Skills: Emotional Intelligence ("EQ") Training for Autistic People and ASD Accommodation Training for People Who Care

for Autism

1 location in Wexford

Sponsor: Kairon Connect, PBC

Sex: All·Age: 18+

Code: NCT07315867·Recruiting

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Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

for Colorectal Anastomosis

8 locations incl. New Haven

Sponsor: Medtronic - MITG

Sex: All·Age: 18+

Code: NCT07351071·Recruiting

Apply to this trial

Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

15 locations incl. Little Rock

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting

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A Dose-ranging Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Galvokimig in Adult Study Participants With Atopic Dermatitis

for Atopic Dermatitis

20 locations incl. Oceanside

Sponsor: UCB Biopharma SRL

Sex: All·Age: 18+

Code: NCT07277660·Phase 2·Recruiting

Apply to this trial

Diagnosing Epilepsy To EffeCT Change

for Epilepsy

18 locations incl. Phoenix

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110337·Recruiting

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Evaluation of a Peer Recovery Support Program Adapted to Target Retention in Clinic-based Medication for Opioid Use Disorder Treatment

for Opioid Use Disorder

1 location in Danville

Sponsor: Geisinger Clinic

Sex: All·Age: 18 - 89

Code: NCT07197801·Recruiting

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Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy

for Bladder Cancer

2 locations incl. Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18 - 85

Code: NCT07234968·Recruiting

Apply to this trial

Psilocybin on Brain Mechanisms of Motivation in OUD

for Opioid Use Disorder

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 60

Code: NCT06810310·Phase 2·Recruiting

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A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

for Breast Neoplasms

117 locations incl. Anchorage

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07174336·Phase 3·Recruiting

Apply to this trial

A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)

for Gout

18 locations incl. Little Rock

Sponsor: Protalix

Sex: All·Age: 18+

Code: NCT07280156·Phase 2·Recruiting

Apply to this trial

Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis (AD)

23 locations incl. Birmingham

Sponsor: Enveda Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07298395·Phase 2·Recruiting

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A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

for Aortic Aneurysm

16 locations incl. Los Angeles

Sponsor: Vascutek Ltd.

Sex: All·Age: 18+

Code: NCT07078383·Recruiting

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A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostatic Neoplasms, Castration-Resistant

Drug: Pasritamig

49 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07225946·Phase 3·Recruiting

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Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS

for Amyotrophic Lateral Sclerosis

7 locations incl. Phoenix

Sponsor: Vector Y Therapeutics

Sex: All·Age: 18+

Code: NCT07287397·Phase 1, Phase 2·Recruiting

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A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

for Spinal Muscular Atrophy (SMA)

17 locations incl. Little Rock

Sponsor: argenx

Sex: All·Age: 5 - 17

Code: NCT07287982·Phase 2·Recruiting

Apply to this trial

NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease

for Graves Disease

8 locations incl. Phoenix

Sponsor: Merida Biosciences

Sex: All·Age: 18 - 55

Code: NCT07305818·Phase 1·Recruiting

Apply to this trial

Intervascular Post-Market Clinical Follow-Up (PMCF) Registry

for Carotid Artery Diseases

1 location in Pittsburgh

Sponsor: Intervascular

Sex: All·Age: 18+

Code: NCT07322913·Recruiting

Apply to this trial