Solid tumor Clinical Trials in Oklahoma City, OK

As of June 2026, 36 paid clinical trials are recruiting for Solid tumor in Oklahoma City, Oklahoma. Recruiting Solid tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

Related specialties in Oklahoma City

Oncology· 274
Filter results
Filter results

36 clinical trials for Solid tumor

·Clear filters·↓ Download CSV

About research studies in Oklahoma City

Oklahoma City has approximately 644 recruiting research studies across a wide range of therapeutic areas. Oklahoma hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.

Top Research Study Locations in Oklahoma City

Researchers run research studies in Oklahoma City, OK at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.

SiteSpecializes inActive trials
University of Oklahoma Health Sciences CenterAcute Myeloid Leukemia, Metastatic Malignant Solid Neoplasm, Stage IV Lung Cancer AJCC v8204
Mercy Hospital Oklahoma CityMalignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v859
University of OklahomaEndometrial Cancer, Colorectal Cancer, Ovarian Cancer28
OU Health Stephenson Cancer CenterOvarian Cancer, AML With Mutated NPM1, Acute Myeloid Leukemia20
Stephenson Cancer CenterBreast Cancer, Cervical Cancer, Endometrial Cancer16
Oklahoma Medical Research FoundationSystemic Lupus Erythematosus, Aging, Multiple Sclerosis13
The University of Oklahoma Health Sciences CenterARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome12
Hightower ClinicalUlcerative Colitis, Antineutrophil Cytoplasmic Antibody-associated Vasculitis, Cancer9
Oklahoma Heart HospitalMitral Regurgitation, Acute Decompensated Heart Failure, Aortic Stenosis9
TSET Health Promotion Research CenterCRC (Colorectal Cancer), CRC Screening, Smoking Cessation8
Integris Southwest Medical CenterStage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma6
Integris Baptist Medical CenterCardiovascular Diseases, Pulmonary Hypertension, Connective Tissue Diseases6
University of Oklahoma Health SciencesAcute Respiratory Distress Syndrome, Breast Cancer Survivor, Cancer Survivorship5
GSK Investigational SiteAlzheimer's Disease, Asthma, Colonic Neoplasms4
Integris Cancer Institute of OklahomaStage IIIB Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma4
Lynn Health Science InstituteMigraine, Obesity or Overweight, Rheumatoid Arthritis4
Oklahoma Children's HospitalAnesthesia, Asthma Attack, Asthma in Children4
Oklahoma Proton CenterBreast Cancer, Breast Neoplasm, Breast Tumor4
South Oklahoma Heart ResearchAcute Coronary Syndrome, Heart Failure, Heart Failure With Mildly Reduced Ejection Fraction4
Unity Clinical ResearchAtopic Dermatitis, Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa4
University of Oklahoma Health CampusBrain Activity, Brain Aging, Cigar Smoking4
University of Oklahoma Health Science CenterAcute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Autoimmune Diseases4
South Oklahoma Heart Research, LLCAcute Myocardial Infarction (AMI), Cardiovascular Risk, Heart Failure3
Dean McGee Eye InstituteChoroidal Melanoma, Indeterminate Lesions, Ocular Melanoma3
Digestive Disease Specialists IncCrohn Disease, Colitis, Ulcerative3

Active & Upcoming Studies in Oklahoma City (2026)

Recruiting trials in Oklahoma City grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.

Cancer & tumors (277 active studies)

Cardiovascular (39 active studies)

Neurology & pain (27 active studies)

Mental health & behavior (25 active studies)

Diabetes & metabolic (24 active studies)

Pediatric (9 active studies)

Vaccines (4 active studies)

Eye & vision (4 active studies)

HIV / STI (1 active study)

Common conditions studied in Oklahoma City

  • Endometrial Cancer (15 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Acute Myeloid Leukemia (13 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
  • Ovarian Cancer (13 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
  • Breast Cancer (10 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
  • Malignant Solid Neoplasm (10 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
  • Major Depressive Disorder (9 active studies). Major depressive disorder research examines rapid-acting agents, augmentation strategies, and digital therapeutics for treatment-resistant cases.

Leading research sponsors in Oklahoma City

  • National Cancer Institute (NCI)
  • University of Oklahoma
  • NRG Oncology
  • SWOG Cancer Research Network
  • Alliance for Clinical Trials in Oncology

Local regulations and guidelines

Clinical trials in Oklahoma are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Oklahoma research additionally follows state public health department oversight and any applicable state privacy statutes.

Compensation & what to expect

How payment typically works
Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
Healthy volunteers
Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Oklahoma City. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
What's included beyond payment
Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
Travel and time
Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
Asking about compensation
Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.

How to find a clinical trial in Oklahoma City

Hipa.ai aggregates every recruiting study in Oklahoma City from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.

Frequently asked questions

How many paid clinical trials are currently recruiting in Oklahoma City?

There are approximately 644 recruiting clinical trials in Oklahoma City, Oklahoma listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Oklahoma City pay participants?

Most recruiting trials in Oklahoma City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Oklahoma City?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Oklahoma City?

The most common conditions under active study in Oklahoma City include Endometrial Cancer (15), Acute Myeloid Leukemia (13), Ovarian Cancer (13), Breast Cancer (10), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Oklahoma City?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Oklahoma City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Oklahoma City?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Oklahoma City?

Recruiting research sites in Oklahoma City include University of Oklahoma Health Sciences Center, Mercy Hospital Oklahoma City, University of Oklahoma, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Oklahoma City right now?

The largest active categories in Oklahoma City are Cancer & tumors (277), Cardiovascular (39), Neurology & pain (27). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

Browse more clinical trials

Other cities in Oklahoma

Tulsa, OK(177)Edmond, OK(32)Lawton, OK(28)Norman, OK(27)Yukon, OK(8)Chickasha, OK(7)Bartlesville, OK(6)Enid, OK(3)Moore, OK(3)Ada, OK(2)Ardmore, OK(2)Elk City, OK(2)Muskogee, OK(2)Stillwater, OK(2)Tahlequah, OK(2)Altus, OK(1)Bethany, OK(1)Canton, OK(1)Duncan, OK(1)Durant, OK(1)Lindsay, OK(1)Multiple Locations, OK(1)

Related healthcare resources in Oklahoma

Latest Oklahoma City, OK clinical trials research report

Trials by condition in Oklahoma City

Endometrial Cancer· 15Acute Myeloid Leukemia· 13Ovarian Cancer· 13Breast Cancer· 10Major Depressive Disorder· 9Asthma· 8