As of June 2026, 164 paid clinical trials are recruiting for Oncology in Oklahoma City, Oklahoma. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Oklahoma City has approximately 644 recruiting research studies across a wide range of therapeutic areas. Oklahoma hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Researchers run research studies in Oklahoma City, OK at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Oklahoma Health Sciences Center | Acute Myeloid Leukemia, Metastatic Malignant Solid Neoplasm, Stage IV Lung Cancer AJCC v8 | 204 |
| Mercy Hospital Oklahoma City | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8 | 59 |
| University of Oklahoma | Endometrial Cancer, Colorectal Cancer, Ovarian Cancer | 28 |
| OU Health Stephenson Cancer Center | Ovarian Cancer, AML With Mutated NPM1, Acute Myeloid Leukemia | 20 |
| Stephenson Cancer Center | Breast Cancer, Cervical Cancer, Endometrial Cancer | 16 |
| Oklahoma Medical Research Foundation | Systemic Lupus Erythematosus, Aging, Multiple Sclerosis | 13 |
| The University of Oklahoma Health Sciences Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 12 |
| Hightower Clinical | Ulcerative Colitis, Antineutrophil Cytoplasmic Antibody-associated Vasculitis, Cancer | 9 |
| Oklahoma Heart Hospital | Mitral Regurgitation, Acute Decompensated Heart Failure, Aortic Stenosis | 9 |
| TSET Health Promotion Research Center | CRC (Colorectal Cancer), CRC Screening, Smoking Cessation | 8 |
| Integris Southwest Medical Center | Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma | 6 |
| Integris Baptist Medical Center | Cardiovascular Diseases, Pulmonary Hypertension, Connective Tissue Diseases | 6 |
| University of Oklahoma Health Sciences | Acute Respiratory Distress Syndrome, Breast Cancer Survivor, Cancer Survivorship | 5 |
| GSK Investigational Site | Alzheimer's Disease, Asthma, Colonic Neoplasms | 4 |
| Integris Cancer Institute of Oklahoma | Stage IIIB Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma | 4 |
| Lynn Health Science Institute | Migraine, Obesity or Overweight, Rheumatoid Arthritis | 4 |
| Oklahoma Children's Hospital | Anesthesia, Asthma Attack, Asthma in Children | 4 |
| Oklahoma Proton Center | Breast Cancer, Breast Neoplasm, Breast Tumor | 4 |
| South Oklahoma Heart Research | Acute Coronary Syndrome, Heart Failure, Heart Failure With Mildly Reduced Ejection Fraction | 4 |
| Unity Clinical Research | Atopic Dermatitis, Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa | 4 |
| University of Oklahoma Health Campus | Brain Activity, Brain Aging, Cigar Smoking | 4 |
| University of Oklahoma Health Science Center | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Autoimmune Diseases | 4 |
| South Oklahoma Heart Research, LLC | Acute Myocardial Infarction (AMI), Cardiovascular Risk, Heart Failure | 3 |
| Dean McGee Eye Institute | Choroidal Melanoma, Indeterminate Lesions, Ocular Melanoma | 3 |
| Digestive Disease Specialists Inc | Crohn Disease, Colitis, Ulcerative | 3 |
Recruiting trials in Oklahoma City grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in Oklahoma are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Oklahoma research additionally follows state public health department oversight and any applicable state privacy statutes.
Hipa.ai aggregates every recruiting study in Oklahoma City from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 644 recruiting clinical trials in Oklahoma City, Oklahoma listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Oklahoma City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Oklahoma City include Endometrial Cancer (15), Acute Myeloid Leukemia (13), Ovarian Cancer (13), Breast Cancer (10), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Oklahoma City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Oklahoma City include University of Oklahoma Health Sciences Center, Mercy Hospital Oklahoma City, University of Oklahoma, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Oklahoma City are Cancer & tumors (277), Cardiovascular (39), Neurology & pain (27). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.