Clinical Trials at Vanderbilt University Medical Center

As of June 2026, 387 paid clinical trials are recruiting at Vanderbilt University Medical Center, located at Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, phone (615) 322-5000 in Nashville, Tennessee. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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387 clinical trials at Vanderbilt University Medical Center

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American Lung Association (ALA) Lung Health Cohort

for Lung Diseases

37 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT04543461·Recruiting

Apply to this trial

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

for Solid Tumor, Adult

16 locations incl. Gilbert

Sponsor: A2 Biotherapeutics Inc.

Sex: All·Age: 18+

Code: NCT04981119·Recruiting

Apply to this trial

Tennessee Alzheimer's Project

for Aging

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT05372172·Recruiting

Apply to this trial

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

for Metastatic Colorectal Cancer

35 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT04929223·Phase 1·Recruiting

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PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

for Aortic Stenosis, Calcific

65 locations incl. Huntsville

Sponsor: Edwards Lifesciences

Sex: All·Age: 65+

Code: NCT04889872·Recruiting

Apply to this trial

Longitudinal Impact of Stressors in Adults With Tourette Syndrome

for Tourette Syndrome

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT04851678·Recruiting

Apply to this trial

Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

for Acute Myocardial Infarction

Drug: Selatogrel

81 locations incl. Alexander City

Sponsor: Viatris Innovation GmbH

Sex: All·Age: 18+

Code: NCT04957719·Phase 3·Enrolling By Invitation

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

for Pheochromocytoma/Paraganglioma

14 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 12+

Code: NCT04924075·Phase 2·Recruiting

Apply to this trial

Neural Correlates of Sensory Phenomena in Tourette Syndrome

for Tourette Syndrome

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03914664·Enrolling By Invitation

Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs

for Liver Diseases

18 locations incl. Los Angeles

Sponsor: European Foundation for Study of Chronic Liver Failure

Sex: All·Age: 18 - 80

Code: NCT04613921·Recruiting

Apply to this trial

SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

for Hemophilia A With Inhibitor

21 locations incl. Phoenix

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: 12 - 100

Code: NCT04647227·Phase 4·Recruiting

Apply to this trial

Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment

for Parkinson Disease

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 40+

Code: NCT04715984·Recruiting

Apply to this trial

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

for Cervical Cancer

11 locations incl. Clovis

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT04895709·Phase 1, Phase 2·Recruiting

Apply to this trial

Goal-Directed Sedation in Mechanically Ventilated Infants and Children

for Delirium

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 44 Weeks - 11

Code: NCT04801589·Phase 3·Recruiting

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Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

for Post Operative Surgical Site Infection

31 locations incl. Redwood City

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 64

Code: NCT04678154·Phase 3·Recruiting

Apply to this trial

Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

for Peripheral Arterial Disease

19 locations incl. New Haven

Sponsor: Population Health Research Institute

Sex: All·Age: 18+

Code: NCT04774159·Phase 3·Recruiting

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Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM

for Symptomatic Hypertrophic Cardiomyopathy (HCM)

Drug: Aficamten

52 locations incl. Birmingham

Sponsor: Cytokinetics

Sex: All·Age: 18 - 85

Code: NCT04848506·Phase 2, Phase 3·Enrolling By Invitation

Neural Correlates of Psychiatric Disorders

for Psychiatric Disorder

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT04725409·Recruiting

Apply to this trial

Genetic Epidemiology of Rotator Cuff Tears: The cuffGEN Study

for Rotator Cuff Tears

10 locations incl. Iowa City

Sponsor: University of Michigan

Sex: All·Age: 40 - 85

Code: NCT04831164·Recruiting

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Enhanced Recovery After Surgery in Extremity Sarcoma

for Sarcoma

1 location in Nashville

Sponsor: Joshua Lawrenz

Sex: All·Age: 18+

Code: NCT04461171·Recruiting

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NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

for Aortic Dissection

31 locations incl. Birmingham

Sponsor: Endospan Ltd.

Sex: All·Age: 18+

Code: NCT04471909·Recruiting

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Disposable Perfusion Phantom for Accurate DCE (Dynamic Contrast Enhanced)-MRI Measurement of Pancreatic Cancer Therapy Response

for Pancreatic Cancer

2 locations incl. Columbus

Sponsor: Ohio State University

Sex: All·Age: 19+

Code: NCT04588025·Recruiting

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Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures

for Congenital Heart Disease in Children

9 locations incl. Los Angeles

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04604418·Recruiting

Apply to this trial

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

71 locations incl. Phoenix

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting

Apply to this trial

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

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Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure

for Supine Hypertension

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 85

Code: NCT04502225·Recruiting

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A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

for Solid Tumor

24 locations incl. Tucson

Sponsor: Eisai Inc.

Sex: All·Age: 18+

Code: NCT04300556·Phase 1, Phase 2·Recruiting

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Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)

for AVB - Atrioventricular Block

23 locations incl. Phoenix

Sponsor: NYU Langone Health

Sex: Female·Age: 18+

Code: NCT04474223·Phase 3·Recruiting

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Impact of Sinus Surgery on Individuals With Cystic Fibrosis

for Chronic Rhinosinusitis (Diagnosis)

9 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 99

Code: NCT04469439·Recruiting

Apply to this trial

HEALEY ALS Platform Trial - Master Protocol

for Amyotrophic Lateral Sclerosis

81 locations incl. Phoenix

Sponsor: Merit E. Cudkowicz, MD

Sex: All·Age: 18+

Code: NCT04297683·Phase 2, Phase 3·Recruiting

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Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma

15 locations incl. La Jolla

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT04429542·Phase 1·Recruiting

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Theophylline for Treatment of Pseudohypoparathyroidism

for Pseudohypoparathyroidism

1 location in Nashville

Sponsor: Jaclyn Tamaroff

Sex: All·Age: 2 - 99·Accepts healthy volunteers

Code: NCT04240821·Phase 2·Enrolling By Invitation

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

for Myelodysplastic Syndromes

Drug: Venetoclax

24 locations incl. Los Angeles

Sponsor: Taiho Oncology, Inc.

Sex: All·Age: 18+

Code: NCT04256317·Phase 2, Phase 3·Recruiting

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Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body

for Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

51 locations incl. Mesa

Sponsor: Bayer

Sex: All·Age: All ages

Code: NCT04142437·Recruiting

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[18F]F-DOPA Imaging in Patients With Autonomic Failure

for Autonomic Failure

1 location in Nashville

Sponsor: Daniel Claassen

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04246437·Phase 1·Recruiting

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Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

for Tricuspid Regurgitation

73 locations incl. Phoenix

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04097145·Recruiting

Apply to this trial

Non-invasive Markers of Esophageal Function in Adults

for Dysphagia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04074356·Enrolling By Invitation

Parallel Versus Perpendicular Technique for Lumbar Medial Branch Radiofrequency Neurotomy

for Back Pain Without Radiation

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 40+

Code: NCT03912519·Enrolling By Invitation

Pan Tumor Rollover Study

for Cancer

59 locations incl. Huntsville

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT03899155·Phase 2·Recruiting

Apply to this trial

GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

for Stroke

45 locations incl. Tucson

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 70

Code: NCT03821129·Recruiting

Apply to this trial