Clinical Trials at Vanderbilt University Medical Center

As of June 2026, 387 paid clinical trials are recruiting at Vanderbilt University Medical Center, located at Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, phone (615) 322-5000 in Nashville, Tennessee. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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387 clinical trials at Vanderbilt University Medical Center

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Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

for Diffuse Astrocytoma, IDH-Mutant

6 locations incl. Beverly Hills

Sponsor: Neonc Technologies, Inc.

Sex: All·Age: 18+

Code: NCT06047379·Phase 1, Phase 2·Recruiting

Apply to this trial

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for Single Ventricle Heart Disease

37 locations incl. Phoenix

Sponsor: Mezzion Pharma Co. Ltd

Sex: All·Age: 12 - 18

Code: NCT05918211·Phase 3·Recruiting

Apply to this trial

Nectero EAST System Clinical Study

for Abdominal Aortic Aneurysm

37 locations incl. Scottsdale

Sponsor: Nectero Medical, Inc.

Sex: All·Age: 21 - 85

Code: NCT06001918·Phase 2, Phase 3·Recruiting

Apply to this trial

Low-dose Buccal Buprenorphine: Relative Abuse Potential and Analgesia

for Analgesia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05988710·Phase 4·Recruiting

Apply to this trial

Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age

for Lymphatic Malformation

10 locations incl. Birmingham

Sponsor: Protara Therapeutics

Sex: All·Age: 6 Months - 18

Code: NCT05871970·Phase 2·Recruiting

Apply to this trial

Neurophysiologic Biomarkers in Rett Syndrome

for Rett Syndrome

6 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: Female·Age: 1 - 18·Accepts healthy volunteers

Code: NCT05932589·Recruiting

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A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction

for Lung Transplant Rejection

32 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06082037·Phase 3·Recruiting

Apply to this trial

Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT

for Microtia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 89

Code: NCT05288790·Phase 2·Recruiting

Apply to this trial

Cryoablation for Monomorphic Ventricular Tachycardia

for Sustained VT

13 locations incl. Phoenix

Sponsor: Adagio Medical

Sex: All·Age: 18+

Code: NCT05675865·Recruiting

Apply to this trial

Biomarker-Led Optimization of Successful Surgical Outcomes in Moyamoya

for Moyamoya Disease

2 locations incl. Baltimore

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 69·Accepts healthy volunteers

Code: NCT06634004·Enrolling By Invitation

Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

for Community-acquired Pneumonia

19 locations incl. Mobile

Sponsor: Biotest

Sex: All·Age: 18+

Code: NCT05722938·Phase 3·Recruiting

Apply to this trial

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

for Chronic Kidney Diseases

2 locations incl. Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 21 - 85

Code: NCT04984226·Phase 2·Recruiting

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Assessment of the Ocular Microbiome in Health and Disease

for Microbial Colonization

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05414994·Recruiting

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The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

for Obesity

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05972564·Phase 1, Phase 2·Recruiting

Apply to this trial

Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer

for Nasolacrimal Duct Obstruction

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05999630·Phase 3·Recruiting

Apply to this trial

Polyethylene-glycol Assisted Nerve Repair in Phalloplasty

for Gender Dysphoria

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18+

Code: NCT05897086·Phase 2, Phase 3·Enrolling By Invitation

Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease

for cGVHD

32 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05919511·Recruiting

Apply to this trial

Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers

for Autism

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 Months - 36 Months

Code: NCT05880225·Recruiting

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Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

19 locations incl. Birmingham

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting

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REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study

for Intra Cerebral Hemorrhage

26 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: All ages

Code: NCT05611918·Enrolling By Invitation

SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery

for Endothelial Dysfunction

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05812755·Phase 4·Recruiting

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Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

for Osteomyelitis Tibia

14 locations incl. Gainesville

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05421741·Phase 4·Recruiting

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A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

for Focal Onset Seizures

19 locations incl. Little Rock

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT05716100·Phase 3·Recruiting

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Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

for Relapsed Non-Hodgkin Lymphoma

32 locations incl. Irvine

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT05826535·Phase 1, Phase 2·Recruiting

Apply to this trial

Platform of Randomized Adaptive Clinical Trials in Critical Illness

for Respiratory Insufficiency

26 locations incl. Tucson

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05440851·Recruiting

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Localized Leiomyosarcoma Biomarker Protocol

for Leiomyosarcoma

3 locations incl. Ann Arbor

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: All ages

Code: NCT04925089·Recruiting

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An Open-label Study of XEN1101 in Epilepsy

for Focal Epilepsy

53 locations incl. Phoenix

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 12+

Code: NCT05718817·Phase 3·Enrolling By Invitation

Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)

for Tachycardia, Ventricular

11 locations incl. Los Angeles

Sponsor: Varian, a Siemens Healthineers Company

Sex: All·Age: 18+

Code: NCT05765175·Recruiting

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Pounce™ Thrombectomy System Retrospective Registry

for Peripheral Arterial Disease

9 locations incl. Peoria

Sponsor: SurModics, Inc.

Sex: All·Age: 18+

Code: NCT05868161·Recruiting

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Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis

for Surgery

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05774717·Phase 1·Recruiting

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VZV in the Enteric Nervous System: Pathogenesis and Consequences

for Achalasia

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 75

Code: NCT05550194·Phase 4·Recruiting

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Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)

for Von Willebrand Diseases

10 locations incl. Los Angeles

Sponsor: Vega Therapeutics, Inc

Sex: All·Age: 12 - 60·Accepts healthy volunteers

Code: NCT05776069·Phase 1, Phase 2·Recruiting

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Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for Alpha1-Antitrypsin Deficiency

37 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT05677971·Phase 3·Recruiting

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Intraoperative Ansa Cervicalis Nerve (ACN) Stimulation

for Head and Neck Cancer

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05650710·Recruiting

Apply to this trial

Splanchnic Venous Capacitance in Postural Tachycardia Syndrome

for Postural Tachycardia Syndrome (POTS)

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05375968·Phase 2·Recruiting

Apply to this trial

REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19

for COVID-19

5 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT05218083·Recruiting

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Canakinumab for the Prevention of Progression to Cancer in Patients With Clonal Cytopenias of Unknown Significance, IMPACT Study

for Clonal Cytopenia of Undetermined Significance

Drug: Canakinumab

6 locations incl. Miami

Sponsor: Uma Borate

Sex: All·Age: 18+

Code: NCT05641831·Phase 2·Recruiting

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Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases

for Neurodegenerative Diseases

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 50 - 85·Accepts healthy volunteers

Code: NCT05357612·Phase 4·Recruiting

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Right Ventricle Lipid in Pulmonary Arterial Hypertension (PAH)

for Idiopathic Pulmonary Arterial Hypertension

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT05462574·Recruiting

Apply to this trial

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

for Urinary Bladder Neoplasms

41 locations incl. Tucson

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05614739·Phase 1·Recruiting

Apply to this trial