Tissue Growth Characterization for Cochlear Implant Usersfor Cochlear Implant1 location in NashvilleSponsor: Vanderbilt University Medical CenterSex: All·Age: 18+Code: NCT04320251·Enrolling By Invitation
GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumabfor Type 1 Diabetes1 location in NashvilleSponsor: Vanderbilt University Medical CenterSex: All·Age: 12 - 50Code: NCT06338553·EARLY_Phase 1·RecruitingApply to this trial
Prospective Clinical Assessment Study in Children With Hypochondroplasiafor Hypochondroplasia8 locations incl. OaklandSponsor: QED Therapeutics, a BridgeBio companySex: All·Age: 30 Months - 16Code: NCT06410976·RecruitingApply to this trial
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinibfor MyelofibrosisDrug: Ruxolitinib58 locations incl. BirminghamSponsor: Kartos Therapeutics, Inc.Sex: All·Age: 18+Code: NCT06479135·Phase 3·RecruitingApply to this trial
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).for PediatricDrug: Aficamten26 locations incl. PhoenixSponsor: CytokineticsSex: All·Age: 12 - 17Code: NCT06412666·Phase 2, Phase 3·RecruitingApply to this trial
VE303 for Prevention of Recurrent Clostridioides Difficile Infectionfor Clostridium Difficile84 locations incl. HuntsvilleSponsor: Vedanta Biosciences, Inc.Sex: All·Age: 12+Code: NCT06237452·Phase 3·RecruitingApply to this trial
Respiratory Strength Training in Heart Transplant Recipientsfor Dysphagia1 location in NashvilleSponsor: Vanderbilt University Medical CenterSex: All·Age: 18 - 90Code: NCT06190171·RecruitingApply to this trial
A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilastfor Idiopathic Pulmonary FibrosisDrug: Nerandomilast58 locations incl. BirminghamSponsor: Boehringer IngelheimSex: All·Age: 18+Code: NCT06238622·Phase 3·RecruitingApply to this trial
REHAB Fontan Failure: A Trial of Cardiac Rehabilitationfor Heart Failure Congenital2 locations incl. StanfordSponsor: Stanford UniversitySex: All·Age: 18+Code: NCT06150950·RecruitingApply to this trial
Platform Clinical Study for Conquering Sclerodermafor Interstitial Lung Disease Due to Systemic Disease34 locations incl. BirminghamSponsor: Scleroderma Research Foundation, Inc.Sex: All·Age: 18+Code: NCT06195072·Phase 2·RecruitingApply to this trial
Intramedullary Calcium Sulfate Antibiotic Depotfor Open tíbia Fracture10 locations incl. Los AngelesSponsor: Wake Forest University Health SciencesSex: All·Age: 18+Code: NCT05766670·Phase 3·RecruitingApply to this trial
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expressionfor Solid Tumor, Adult12 locations incl. GilbertSponsor: A2 Biotherapeutics Inc.Sex: All·Age: 18+Code: NCT06051695·Phase 1, Phase 2·RecruitingApply to this trial
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myelomafor Multiple Myeloma41 locations incl. BirminghamSponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb CompanySex: All·Age: 18+Code: NCT06297226·Phase 2·RecruitingApply to this trial
Wearable Technology to Evaluate Hyperglycemia and HRV in DMDfor Duchenne Muscular Dystrophy1 location in NashvilleSponsor: Vanderbilt University Medical CenterSex: Male·Age: 10+·Accepts healthy volunteersCode: NCT06124196·RecruitingApply to this trial
Tranexamic Acid in Nasal Mohs Reconstructionfor Postoperative Bleeding1 location in NashvilleSponsor: Vanderbilt University Medical CenterSex: All·Age: 18+·Accepts healthy volunteersCode: NCT06057675·Phase 2·RecruitingApply to this trial
ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantationfor Aortic Valve Stenosis67 locations incl. BirminghamSponsor: Abbott Medical DevicesSex: All·Age: 18+Code: NCT05932615·Enrolling By Invitation
A Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsyfor Focal EpilepsyDrug: BHV-700061 locations incl. PhoenixSponsor: Biohaven Therapeutics Ltd.Sex: All·Age: 18 - 75Code: NCT06132893·Phase 2, Phase 3·RecruitingApply to this trial
Telehealth-enhanced Patient-oriented Recovery Trajectory After Intensive Carefor Post-intensive Care Syndrome2 locations incl. ColumbusSponsor: Vanderbilt UniversitySex: All·Age: 45+Code: NCT06014931·RecruitingApply to this trial
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.for Oligometastatic Prostate Cancer (OMPC)41 locations incl. FayettevilleSponsor: Novartis PharmaceuticalsSex: Male·Age: 18 - 100Code: NCT05939414·Phase 3·RecruitingApply to this trial
Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancerfor Stage III Ovarian CancerDrug: Niraparib59 locations incl. DuarteSponsor: GOG FoundationSex: Female·Age: 18+Code: NCT05659381·Phase 3·RecruitingApply to this trial
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemiafor AML38 locations incl. GilbertSponsor: Kura Oncology, Inc.Sex: All·Age: 18+Code: NCT06001788·Phase 1·RecruitingApply to this trial
The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registryfor Cesarean Delivery34 locations incl. Little RockSponsor: Yale UniversitySex: Female·Age: 15 - 55·Accepts healthy volunteersCode: NCT06030063·RecruitingApply to this trial
Gram-Negative Bloodstream Infection Oral Antibiotic Therapy Trialfor Gram-negative Bacteremia11 locations incl. San FranciscoSponsor: Johns Hopkins UniversitySex: All·Age: 18+Code: NCT06080698·RecruitingApply to this trial
Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) Systemfor Tricuspid Regurgitation6 locations incl. TucsonSponsor: Laplace Interventional, IncSex: All·Age: 22 - 90Code: NCT06183684·RecruitingApply to this trial
DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatmentfor Ductal Carcinoma in Situ28 locations incl. BerkeleySponsor: QuantumLeap Healthcare CollaborativeSex: Female·Age: 18+Code: NCT06075953·Phase 2·RecruitingApply to this trial
2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH)for Familial Hypercholesterolemia1 location in NashvilleSponsor: Vanderbilt University Medical CenterSex: All·Age: 18 - 69Code: NCT04941599·Phase 2·RecruitingApply to this trial
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitisfor Antineutrophil Cytoplasmic Antibody-associated VasculitisDrug: Avacopan60 locations incl. AnchorageSponsor: AmgenSex: All·Age: 18 - 100Code: NCT06072482·Phase 4·RecruitingApply to this trial
An Observational Study Comparing Delandistrogene Moxeparvovec (ELEVIDYS) With Standard of Care in Participants With Duchenne Muscular Dystrophyfor Duchenne Muscular Dystrophy25 locations incl. Little RockSponsor: Sarepta Therapeutics, Inc.Sex: Male·Age: 4+Code: NCT06270719·Enrolling By Invitation
Function After Anterior Cervical Discectomy and Fusion Surgery: Timing of Physical Therapyfor Cervical Spine Degeneration4 locations incl. HonoluluSponsor: Vanderbilt University Medical CenterSex: All·Age: 18 - 75Code: NCT06202443·RecruitingApply to this trial
Retinal Vascular Changes During Pregnancyfor Pregnancy1 location in NashvilleSponsor: Vanderbilt University Medical CenterSex: Female·Age: 18+Code: NCT06311617·RecruitingApply to this trial
Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)for WheezingDrug: Dupilumab14 locations incl. PhoenixSponsor: SanofiSex: All·Age: 2 - 5Code: NCT06191315·Phase 3·RecruitingApply to this trial
Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)for Acute Compartment Syndrome4 locations incl. BaltimoreSponsor: Major Extremity Trauma Research ConsortiumSex: All·Age: 18 - 60Code: NCT05889559·RecruitingApply to this trial
Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventionsfor Valvular Heart Disease1 location in NashvilleSponsor: Vanderbilt University Medical CenterSex: All·Age: 18+Code: NCT06077201·RecruitingApply to this trial
Defining the Risk of Ventricular Tachycardia in Genetic Cardiomyopathiesfor Atrial Fibrillation1 location in NashvilleSponsor: Vanderbilt University Medical CenterSex: All·Age: 18+Code: NCT06575881·RecruitingApply to this trial
A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphomafor Follicular Lymphoma (FL)Drug: Odronextamab20 locations incl. TucsonSponsor: Regeneron PharmaceuticalsSex: All·Age: 18+Code: NCT06091254·Phase 3·RecruitingApply to this trial
A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasmsfor Myeloproliferative NeoplasmsDrug: Ruxolitinib13 locations incl. DuarteSponsor: Incyte CorporationSex: All·Age: 18+Code: NCT06034002·Phase 1·RecruitingApply to this trial
Early Use of Long-acting Tacrolimus in Lung Transplant Recipientsfor Lung Transplant1 location in NashvilleSponsor: Vanderbilt University Medical CenterSex: All·Age: 18+Code: NCT04469842·EARLY_Phase 1·RecruitingApply to this trial
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagusfor Esophageal Stricture34 locations incl. BirminghamSponsor: GIE MedicalSex: All·Age: 22+Code: NCT05561114·Phase 3·RecruitingApply to this trial
Treatment With Endovascular Intervention for STroke Patients With Existing Disabilityfor Stroke25 locations incl. PhoenixSponsor: University of CincinnatiSex: All·Age: 18+Code: NCT05911568·RecruitingApply to this trial
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowelfor Bowel33 locations incl. ScottsdaleSponsor: GIE MedicalSex: All·Age: 22+Code: NCT05561127·Phase 3·RecruitingApply to this trial