Clinical Trials at Vanderbilt University Medical Center

As of June 2026, 387 paid clinical trials are recruiting at Vanderbilt University Medical Center, located at Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, phone (615) 322-5000 in Nashville, Tennessee. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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387 clinical trials at Vanderbilt University Medical Center

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Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)

for Brain Cancer

Drug: Nivolumab

1 location in Nashville

Sponsor: Eben Rosenthal

Sex: All·Age: 18+

Code: NCT07210632·EARLY_Phase 1·Recruiting

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The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms

for Hemorrhagic Stroke

17 locations incl. Phoenix

Sponsor: phenox Inc.

Sex: All·Age: 18+

Code: NCT07143019·Recruiting

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A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)

for Hepatocellular Carcinoma (HCC)

Drug: Ipilimumab

9 locations incl. Los Angeles

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07291076·Phase 1, Phase 2·Recruiting

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Endoscopic COlorectal Mucosal Evaluation of Oxygen Tension

for Anastomotic Leak Rectum

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07467980·Recruiting

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A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

for Parkinson Disease

25 locations incl. Little Rock

Sponsor: Appello Pharmaceuticals, Inc.

Sex: All·Age: 30 - 80

Code: NCT07432958·Phase 2·Recruiting

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Rehabilitation With Empowered STrategies to Optimize REcovery

for Lumbar Spine Degenerative Changes

4 locations incl. Honolulu

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 85

Code: NCT07406997·Recruiting

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Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

for Chronic Obstructive Pulmonary Disease (COPD)

Drug: Omalizumab

23 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 40+

Code: NCT07059091·Phase 2·Recruiting

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Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS

for Short Bowel Syndrome

4 locations incl. St Louis

Sponsor: Zealand Pharma

Sex: All·Age: 18 - 90

Code: NCT07197944·Phase 3·Recruiting

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A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

for Familial Pulmonary Fibrosis

Drug: Nerandomilast

13 locations incl. Los Angeles

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07201922·Phase 3·Recruiting

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A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury

for Traumatic Brain Injury

13 locations incl. Sacramento

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07455136·Recruiting

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Metastatic Ewing's Trial Testing Schedule Enhancement to Improve Outcomes

for Metastatic Ewing Sarcoma

17 locations incl. Birmingham

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 1+

Code: NCT07194044·Phase 1·Recruiting

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NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE)

for Postpartum Depression (PPD)

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07214597·Recruiting

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Registry Study for the Evaluation of High-risk Cardiac Patients by WILLEM AI-based ECG Platform

for High-risk Cardiac Patients

1 location in Nashville

Sponsor: Idoven 1903 S.L.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07333547·Recruiting

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Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease

for Huntington Disease

2 locations incl. Rochester

Sponsor: BioSensics

Sex: All·Age: 25 - 65·Accepts healthy volunteers

Code: NCT07315984·Not Yet Recruiting

Increasing Germline Genetic Testing for Patients With Cancer

for Hereditary Pancreatic Cancer

10 locations incl. Los Angeles

Sponsor: Josh Peterson

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07307664·Recruiting

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Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

for Opioid Use Disorder

Drug: Tirzepatide

9 locations incl. Jacksonville

Sponsor: T. John Winhusen, PhD

Sex: All·Age: 18+

Code: NCT06651177·Phase 2·Recruiting

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Digoxin Medulloblastoma Study

for Medulloblastoma

15 locations incl. Birmingham

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 12 Months - 30

Code: NCT06701812·Phase 2·Recruiting

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Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema

for Head and Neck Cancer

2 locations incl. Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06837480·Recruiting

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Lead Evaluation for Defibrillation and Reliability Post Approval Study

for Tachyarrhythmia

46 locations incl. Birmingham

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT07005232·Enrolling By Invitation

Hyperangulated Versus Standard Geometry Laryngoscope Blade Trial

for Acute Respiratory Failure

16 locations incl. Los Angeles

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07223762·Enrolling By Invitation

AI-driven Clinical Decision Support to Reduce Hospital-Acquired Venous Thromboembolism: Study Protocol for the VTE-AI Randomized Trial.

for Venothromboembolism

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: All ages

Code: NCT06939803·Recruiting

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A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

for Focal Epilepsy

7 locations incl. Boise

Sponsor: Rapport Therapeutics Inc.

Sex: All·Age: 18 - 70

Code: NCT07219407·Phase 2·Recruiting

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A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

for Clostridioides Difficile Associated Disease

135 locations incl. Athens

Sponsor: Pfizer

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT07282665·Phase 3·Recruiting

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A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

for Chronic Kidney Disease

Drug: Empagliflozin

30 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07107945·Phase 3·Recruiting

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A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

for Squamous Cell Carcinoma of Head and Neck

Drug: Amivantamab

41 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07276399·Phase 3·Recruiting

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Impact of Intraoperative Oxygenation Practices on Patient Outcomes

for Surgeries Undergoing General Anesthesia

4 locations incl. Ann Arbor

Sponsor: Frederic T Billings IV

Sex: All·Age: 18+

Code: NCT07224243·Recruiting

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Observational Study of VYKAT™ XR in Patients With Prader-Willi Syndrome

for Prader-Willi Syndrome

15 locations incl. Los Angeles

Sponsor: Soleno Therapeutics, Inc.

Sex: All·Age: 4+

Code: NCT07450664·Enrolling By Invitation

Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

for Bladder Cancer

6 locations incl. Tampa

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT07225127·Recruiting

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Bevacizumab

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701656·Phase 2·Recruiting

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A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer

for Colorectal Cancer

9 locations incl. New Haven

Sponsor: Criterium, Inc.

Sex: All·Age: 18+

Code: NCT06992258·Phase 2·Recruiting

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A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

for Ovarian Neoplasms

82 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213804·Phase 3·Recruiting

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A Study of JNT-517 in Participants With Phenylketonuria (PKU)

for Phenylketonuria

10 locations incl. Los Angeles

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 18+

Code: NCT06971731·Phase 3·Recruiting

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STrong Relationships to Improve DiabEtes Pilot

for Type 2 Diabetes

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 75

Code: NCT07210593·Enrolling By Invitation

Subcortical Arousal in Perceptual Awareness

for Epilepsy

8 locations incl. New Haven

Sponsor: Yale University

Sex: All·Age: 13+

Code: NCT06934356·Recruiting

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Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells

for Glucose

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06930976·Recruiting

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High vs. Standard Dose Influenza Vaccines in Lung Transplant (Repeater)

for Immunization

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07192458·Phase 2·Recruiting

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Validation of Donor-Derived Cell-Free DNA (Dd-cfDNA) for Kidney Transplant Monitoring

for Kidney Transplant Rejection

8 locations incl. Los Angeles

Sponsor: Insight Molecular Diagnostics

Sex: All·Age: 18+

Code: NCT07060716·Recruiting

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High-Resolution PET-CT Imaging for Surgical Margin Visualization

for Cancer

1 location in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT06915454·Recruiting

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Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial

for Postoperative Nausea

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07152249·Recruiting

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Sentence Shaping - DHH

for Hearing Loss, Bilateral

1 location in Nashville

Sponsor: Vanderbilt University

Sex: All·Age: 9 - 15

Code: NCT06860022·Recruiting

Apply to this trial