Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells

Part of paid clinical trials in Nashville, Tennessee.

Sponsor
Vanderbilt University Medical Center
Study ID
NCT06930976
Status
Recruiting
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Conditions

  • Glucose
  • Immune System and Related Disorders
  • Isotope Labeling
  • Metabolism

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • 13C6-Glucose — DRUG
    Compounded as 5% 13C6-Glucose in sterile water given IV over 2-4 hours as a split bolus and infusion

Study Details

The purpose of this study is to understand how cells of the immune system use the common sugar glucose to fuel energy production and as a building block within the cell. Investigators will intravenously infuse a non-radioactive glucose tracer into participants over a few hours and collect immune cells from the blood to track uptake and usage of this glucose within these immune cells.

Key Dates

Start date
Oct 1, 2025
Status verified
Oct 2025
Primary completion
Jun 30, 2027
Completion
Jun 30, 2027

Study Design

Enrollment
12 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Other: 13C6-Glucose
    10-25gm of 13C6-Glucose

Primary Outcome Measure

13C6-glucose uptake in immune cells [ Time Frame: Up to 4 hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Vanderbilt University Medical CenterNashvilleTennessee37212-

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Vanderbilt University Medical Center· Nashville, TN

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