Paid Clinical Trials in Minnesota

Minnesota has 2,364 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,364 clinical trials

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AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF

for Symptomatic Heart Failure With Preserved Ejection Fraction (HFpEF)

25 locations incl. Fairhope

Sponsor: Cytokinetics

Sex: All·Age: 40 - 85

Code: NCT06793371·Phase 2·Recruiting

Apply to this trial

Feasibility of a First-Line Physical Activity Intervention After Stroke

for Stroke

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06679803·Enrolling By Invitation

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

for Malignant Brain Neoplasm

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06788886·Recruiting

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A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for Proteinuric Kidney Disease

Drug: MZE829

72 locations incl. Decatur

Sponsor: Maze Therapeutics

Sex: All·Age: 18 - 68

Code: NCT06830629·Phase 2·Recruiting

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A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for Recurrent Childhood Acute Myeloid Leukemia

19 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 18

Code: NCT06247787·Phase 1·Recruiting

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BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS

for AML, Adult Recurrent

6 locations incl. Duarte

Sponsor: BlueSphere Bio, Inc

Sex: All·Age: 18 - 70

Code: NCT06704152·Phase 1, Phase 2·Recruiting

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A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for KRAS G12C Mutation

11 locations incl. Phoenix

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06720987·Phase 1·Recruiting

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EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

for Glioblastoma

32 locations incl. Phoenix

Sponsor: NovoCure GmbH

Sex: All·Age: 18+

Code: NCT06556563·Phase 3·Recruiting

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Effect of Sacubitril-Valsartan on Cardiac Structure and Function

for Congenital Heart Disease

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06693674·Phase 3·Recruiting

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DESIFOR-EXPAND (MHIF)

for Statin Therapy

1 location in Minneapolis

Sponsor: Minneapolis Heart Institute Foundation

Sex: All·Age: 21+

Code: NCT06804980·Phase 4·Recruiting

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A Study of Carbon 13-based Deep Labelling of Bone Marrow Cells

for Monoclonal Gammopathy of Undetermined Significance (MGUS)

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07057583·Enrolling By Invitation

StrokeNet Thrombectomy Endovascular Platform

for Ischemic Stroke

41 locations incl. Birmingham

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06289985·Recruiting

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BOOM-IBD2 Pivotal Clinical Trial

for Ulcerative Colitis

19 locations incl. Folsom

Sponsor: Boomerang Medical

Sex: All·Age: 18 - 85

Code: NCT06571669·Recruiting

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Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

for Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer

3 locations incl. Westwood

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06374459·Phase 1, Phase 2·Recruiting

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

464 locations incl. Fairbanks

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting

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Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

for Anaplastic Large Cell Lymphoma, ALK-Negative

158 locations incl. Birmingham

Sponsor: Eastern Cooperative Oncology Group

Sex: All·Age: 18 - 75

Code: NCT06724237·Phase 3·Recruiting

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

for Metastatic Head and Neck Squamous Cell Carcinoma

53 locations incl. Birmingham

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT06788990·Phase 2, Phase 3·Recruiting

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An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis

for Recurrent Pericarditis

17 locations incl. Tucson

Sponsor: Zomagen Biosciences Ltd.

Sex: All·Age: 18 - 75

Code: NCT06836232·Phase 2·Recruiting

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US National TOP Registry

for Lung Transplant

7 locations incl. Phoenix

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT06513091·Recruiting

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Phenotype-Tailored Lifestyle Intervention for Obesity: A Randomized Trial

for Obesity

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 65

Code: NCT06770049·Recruiting

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A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy

for Geographic Atrophy

65 locations incl. Phoenix

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: All ages

Code: NCT06779773·Recruiting

Apply to this trial

Real World Observational Study of Sotatercept for Pulmonary Hypertension

for Pulmonary Hypertension

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06751082·Recruiting

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Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study

for Left Ventricular Systolic Dysfunction

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06770062·Recruiting

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Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma

for Vestibular Schwannoma

4 locations incl. Baltimore

Sponsor: Akouos, Inc.

Sex: All·Age: 18+

Code: NCT06517888·Phase 1, Phase 2·Recruiting

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A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

for Parkinson Disease

45 locations incl. Sun City

Sponsor: Neuron23 Inc.

Sex: All·Age: 40 - 80

Code: NCT06680830·Phase 2·Recruiting

Apply to this trial

Referral Training and eGen Trials

for Behavioral Problem

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06695663·Recruiting

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Brain Training for Substance Use Disorders

for Opioid Use Disorder

1 location in Minneapolis

Sponsor: Neurotype Inc.

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06870110·Recruiting

Apply to this trial

Biomarkers of Resiliency In Childhood Cancer Surgery

for Pediatric Cancer

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 3 - 25

Code: NCT06674811·Recruiting

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Standardized Microbiota Transplant Therapy in Crohn's Disease

for Crohn Disease

2 locations incl. Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 89

Code: NCT06631586·Phase 2·Recruiting

Apply to this trial

Targeting Transdiagnostic Self-regulatory Factors and Eating Disorder Pathology Among Adults With BInge-spectrum Eating disOrders: A mHEALTH Interoceptive Exposure Intervention (the Bio-HEALTH Study)

for Eating Disorders

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 64

Code: NCT06631729·Recruiting

Apply to this trial

Exploration of HRQOL and Urinary Outcomes Following Partial Cystectomy

for Bladder Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06891209·Recruiting

Apply to this trial

Mechanisms of Anabolic Resistance in Older Humans

for Aging

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 21 - 85·Accepts healthy volunteers

Code: NCT06617195·Recruiting

Apply to this trial

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

for Melanoma, Cutaneous Malignant

40 locations incl. Phoenix

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT06743126·Phase 3·Recruiting

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Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

for Adult Growth Hormone Deficiency

17 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 21 - 55

Code: NCT04867317·Phase 3·Recruiting

Apply to this trial

AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)

for Phenylketonurias

5 locations incl. Orange

Sponsor: NGGT INC.

Sex: All·Age: 18 - 55

Code: NCT06332807·Phase 1, Phase 2·Recruiting

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Cryo Rib Fracture Study

for Rib Fractures

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06347874·Phase 4·Recruiting

Apply to this trial

PACTAID App in Adults With Type 1 Diabetes to Help Manage Exercise

for Type 1 Diabetes Mellitus

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 65

Code: NCT06730906·Enrolling By Invitation

A Prospective, Randomized Comparison Of Drainage Techniques After One- Or Two-Level Open Posterior Lumbar Decompression Or Decompression And Fusion

for Complications, Postoperative

1 location in Minneapolis

Sponsor: Twin Cities Spine Center

Sex: All·Age: 18 - 70

Code: NCT06820736·Recruiting

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A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

for NSCLC (Advanced Non-small Cell Lung Cancer)

23 locations incl. Phoenix

Sponsor: BlossomHill Therapeutics

Sex: All·Age: 18+

Code: NCT06706076·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

for Arthritis, Psoriatic

23 locations incl. Glendale

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06807424·Phase 3·Recruiting

Apply to this trial