A Study of Carbon 13-based Deep Labelling of Bone Marrow Cells

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT07057583
Status
Enrolling By Invitation

Conditions

  • Monoclonal Gammopathy of Undetermined Significance (MGUS)
  • Non-IgM Monoclonal Gammopathy of Undetermined Significance

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Non-Interventional Study — OTHER
    Non-interventional study

Study Details

This study evaluates a novel laboratory method to study how certain bone marrow cells in the body take up nutrients from their environment.

Key Dates

Start date
Feb 1, 2025
Status verified
Dec 2025
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
40 participants (estimated)

Arms

  • Arm: Observational Group I
    Patients undergo blood collection and bone marrow aspiration as part of their standard care and have their medical records reviewed on study.
  • Arm: Observational Group II
    Healthy volunteers undergo blood collection and bone marrow aspiration on study.

Primary Outcome Measure

Extracellular uptake of glucose and amino acids (AAs) between pre-malignant clonal plasma cells (cPCs) and polyclonal plasma cells (pPCs) [ Time Frame: Up to 30 days ]

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in RochesterRochesterMinnesota55905-

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By research site
Mayo Clinic in Rochester· Rochester, MN

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