Paid Clinical Trials in Minnesota

Minnesota has 2,364 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,364 clinical trials

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Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial

for Locally Advanced Bladder Urothelial Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06764095·Phase 4·Recruiting

Apply to this trial

Utility of Random Biopsies in Patients With Inflammatory Bowel Disease

for Inflammatory Bowel Diseases

20 locations incl. Birmingham

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06560021·Enrolling By Invitation

Probiotic in Patients With Bile Acid Malabsorption/Diarrhea

for Bile Acid Malabsorption

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06609148·Recruiting

Apply to this trial

Corticosteroid Injection Versus Nerve Block

for Glenohumeral Arthritis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 99

Code: NCT06735027·Recruiting

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Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

for Oral Leukoplakia

2 locations incl. Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05727761·Phase 2·Recruiting

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Utility and Effectiveness of Polygenic Risk Scoring (PRS) for Coronary Artery Disease (CAD)

for Coronary Artery Disease

2 locations incl. Rochester

Sponsor: MyOme

Sex: All·Age: 40 - 70

Code: NCT06542432·Enrolling By Invitation

Safety and Effectiveness of the Akura Thrombectomy System for Use in the Removal of Emboli From the Pulmonary Arteries in Treating Acute Pulmonary Embolism (PE)

for Pulmonary Embolism Acute

12 locations incl. Thousand Oaks

Sponsor: Akura Medical

Sex: All·Age: 18+

Code: NCT06672510·Recruiting

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A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

for Treatment Resistant Depression

34 locations incl. Tucson

Sponsor: atai Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06524830·Phase 2·Recruiting

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A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

for Advanced Hepatocellular Carcinoma

16 locations incl. Phoenix

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06600321·Phase 1·Recruiting

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A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors

for Solid Tumors

8 locations incl. Duarte

Sponsor: Adcentrx Therapeutics

Sex: All·Age: 18+

Code: NCT06710379·Phase 1·Recruiting

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Adenovirus (RGDCRAdCOX2F)

for Adenocarcinoma of Pancreas

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT06693986·Phase 1·Recruiting

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TMS Pilot in Early AD II

for Alzheimer Disease

1 location in Saint Paul

Sponsor: HealthPartners Institute

Sex: All·Age: 40 - 90

Code: NCT06817902·Enrolling By Invitation

ECD-Score: a Study on Erdheim-Chester Disease

for Erdheim-Chester Disease (ECD)

3 locations incl. Bethesda

Sponsor: Meyer Children's Hospital IRCCS

Sex: All·Age: 7+

Code: NCT07454343·Recruiting

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Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium

for Delirium on Emergence

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 2 - 7

Code: NCT06624592·Phase 3·Recruiting

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Clinical Data Collection for Obstetric Ultrasound Algorithms

for Pregnancy

2 locations incl. Minneapolis

Sponsor: Caption Health, Inc.

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06742229·Not Yet Recruiting

A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

for Focal Segmental Glomerulosclerosis

Drug: Brivekimig

16 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 16 - 75

Code: NCT06500702·Phase 2·Recruiting

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A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

for Metastatic Uveal Melanoma

Drug: Nivolumab

29 locations incl. Scottsdale

Sponsor: Replimune, Inc.

Sex: All·Age: All ages

Code: NCT06581406·Phase 2, Phase 3·Recruiting

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Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

for IgA Nephropathy

37 locations incl. Birmingham

Sponsor: Calliditas Therapeutics AB

Sex: All·Age: 18+

Code: NCT06712407·Phase 4·Recruiting

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A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for Graves' Disease

Drug: IMVT-1402

64 locations incl. Phoenix

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 75

Code: NCT06727604·Phase 2·Recruiting

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RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for Osteoporosis

23 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT06455085·Recruiting

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Suprachoroidal Administration in Subjects With Metastases to the Choroid

for Eye Cancer

10 locations incl. Palo Alto

Sponsor: Aura Biosciences

Sex: All·Age: 18+

Code: NCT06643884·Phase 2·Recruiting

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A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

Drug: Amivantamab

150 locations incl. Daphne

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06667076·Phase 2·Recruiting

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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

57 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting

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First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

for Advanced Solid Tumors

12 locations incl. New Haven

Sponsor: Tubulis GmbH

Sex: All·Age: 18+

Code: NCT06657222·Phase 1, Phase 2·Recruiting

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Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

for Pancreatic Carcinoma

9 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06271291·Recruiting

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Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer

for Endometrial Cancer

18 locations incl. La Jolla

Sponsor: Faeth Therapeutics

Sex: Female·Age: 18+

Code: NCT06463028·Phase 2·Recruiting

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Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

for Anatomic Stage IV Breast Cancer AJCC v8

256 locations incl. Tucson

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500455·Phase 3·Recruiting

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Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure

for Hypertension

Drug: Empagliflozin

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 60+

Code: NCT06507657·EARLY_Phase 1·Recruiting

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A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

for Asthma

85 locations incl. Phoenix

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 12+

Code: NCT06664619·Phase 3·Recruiting

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A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.

for Candidemia

23 locations incl. Birmingham

Sponsor: Basilea Pharmaceutica

Sex: All·Age: 18+

Code: NCT05421858·Phase 3·Recruiting

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Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

for Resectable Lung Non-Small Cell Carcinoma

378 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06632327·Phase 3·Recruiting

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Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy

for Hematopoietic and Lymphatic System Neoplasm

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06723041·Recruiting

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Support for Transgender and Non-Binary Individuals Seeking Vaginoplasty Study

for Gender Affirmation Surgery

9 locations incl. San Francisco

Sponsor: Oregon Health and Science University

Sex: Male·Age: 18+

Code: NCT06436560·Enrolling By Invitation

A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST)

for Gastrointestinal Stromal Tumor (GIST)

10 locations incl. Scottsdate

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06630234·Phase 1, Phase 2·Recruiting

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The JenaValve ALIGN-AR LVAD Registry

for Aortic Regurgitation

15 locations incl. Los Angeles

Sponsor: JenaValve Technology, Inc.

Sex: All·Age: 18+

Code: NCT06594705·Recruiting

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A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

6 locations incl. Los Angeles

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06625593·Phase 1·Recruiting

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Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer

for Locally Advanced Pancreatic Adenocarcinoma

Drug: Verteporfin

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06381154·Phase 2·Recruiting

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Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple Myeloma

for Recurrent Multiple Myeloma

Drug: Teclistamab

14 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06465316·Phase 1·Recruiting

Apply to this trial

3D DL Ozteo in the Detection of Osseous Changes in Patients With Inflammatory Arthritis

for Inflammatory Arthritis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06383585·Recruiting

Apply to this trial

MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma

for Autologous Stem Cell Transplant

1 location in Minneapolis

Sponsor: Masonic Cancer Center, University of Minnesota

Sex: All·Age: 18+

Code: NCT06377540·Phase 2·Recruiting

Apply to this trial