Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT06624592
Phase
PHASE3
Status
Recruiting

Conditions

  • Delirium on Emergence

Eligibility Criteria

Sex
ALL
Age
2 Years - 7 Years
Healthy Volunteers
Not accepted

Interventions

  • Sevoflurane — DRUG
    Subjects will receive standard of care anesthesia Sevoflurane, with intravenous push Dexmedetomidine
  • Isoflurane — DRUG
    Subjects will receive standard of care anesthesia Isoflurane

Study Details

The purpose of this study is to measure the incidences of pediatric emergence delirium between the group receiving Isoflurane and the group receiving Sevoflurane plus intravenous push dexmedetomidine.

Key Dates

Start date
Dec 20, 2024
Status verified
Dec 2025
Primary completion
Nov 1, 2026
Completion
Nov 1, 2026

Study Design

Enrollment
400 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Isoflurane group
  • Active Comparator: Sevoflurane group

Primary Outcome Measure

Number of subjects with emergence delirium [ Time Frame: Within 1 hour after dropped off by anesthesiology team ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in RochesterRochesterMinnesota55905
Lindsay Warner (PRINCIPAL_INVESTIGATOR)

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