Paid Clinical Trials in Minnesota

Minnesota has 2,364 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,364 clinical trials

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Alleviant ALLAY-HFrEF Study

for Heart Failure

35 locations incl. Los Angeles

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 18+

Code: NCT06812533·Enrolling By Invitation

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-Resistant Prostate Cancer

12 locations incl. Palo Alto

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT06879041·Phase 1·Recruiting

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Parent-Child EF Intervention

for Cognitive Intervention to Promote Healthy Development of Executive Function (EF) Skills in Young Children

2 locations incl. Minneapolis

Sponsor: Koronis Biomedical Technologies

Sex: All·Age: 2 - 5·Accepts healthy volunteers

Code: NCT06924307·Recruiting

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Effect of Vibro-tactile Stimulation Intensity on Head Posture in Cervical Dystonia

for Cervical Dystonia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT07245615·Recruiting

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52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism

for Hypogonadism, Male

20 locations incl. Los Angeles

Sponsor: Halozyme Therapeutics

Sex: Male·Age: 12 - 17

Code: NCT06689085·Phase 3·Recruiting

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Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

for Non Small Cell Lung Carcinoma

26 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06772623·Phase 1, Phase 2·Recruiting

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Rilonacept in Subjects With Cardiac Sarcoidosis

for Cardiac Sarcoidosis

2 locations incl. Baltimore

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80

Code: NCT06660732·Phase 2·Recruiting

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A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

for Mantle Cell Lymphoma

Drug: Sonrotoclax

37 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06742996·Phase 3·Recruiting

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Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease

for APOL1-Mediated Kidney Disease

67 locations incl. Alabaster

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65

Code: NCT06824987·Phase 2·Recruiting

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Weight Loss Through Mayo Clinic Diet

for Obesity

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT06862375·Recruiting

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Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

for Anatomic Stage IV Breast Cancer AJCC v8

58 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06500481·Phase 3·Recruiting

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Home-based Pulmonary Rehabilitation and Health Coaching in Patients With Fibrotic Interstitial Lung Disease

for Lung Fibrosis

4 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06751069·Recruiting

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A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

for Multiple System Atrophy

6 locations incl. Los Angeles

Sponsor: Dasher Neuroscience Inc.

Sex: All·Age: 30+

Code: NCT06848231·Phase 2·Recruiting

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A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

for HER2-positive Gastric Cancer

Drug: Rilvegostomig

53 locations incl. Anchorage

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06764875·Phase 3·Recruiting

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Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0

for Acute Kidney Injury

50 locations incl. Birmingham

Sponsor: Indiana University

Sex: All·Age: 0 Minutes - 2 Weeks

Code: NCT06823115·Enrolling By Invitation

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

for Hidradenitis Suppurativa (HS)

Drug: Povorcitinib

108 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06855498·Phase 3·Recruiting

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Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

190 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting

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CBIT+TMS R33 Phase

for Tics

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 12 - 21

Code: NCT06678737·Phase 2·Recruiting

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Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

for Gastric Cancer

18 locations incl. New Haven

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06731478·Phase 3·Recruiting

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Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

for Non-Small Cell Lung Cancer

Drug: Ivonescimab

89 locations incl. Chandler

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT06767514·Phase 3·Recruiting

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I CAN DO Surgical ACP

for Surgical Advanced Care Planning

3 locations incl. Irvine

Sponsor: University of California, San Francisco

Sex: All·Age: 65+

Code: NCT06090552·Recruiting

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A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults

for Healthy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 60 - 85·Accepts healthy volunteers

Code: NCT06820658·Recruiting

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A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

for Extensive-Stage Small Cell Lung Cancer

Drug: Atezolizumab

20 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06646276·Phase 3·Recruiting

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An Extension Study to Evaluate Safety and Efficacy in Participants Treated With CRN04894

for Congenital Adrenal Hyperplasia

2 locations incl. Minneapolis

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 16+

Code: NCT06712823·Phase 2·Recruiting

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Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant

for E Coli Infections

8 locations incl. Duarte

Sponsor: SNIPR Biome Aps.

Sex: All·Age: 18+

Code: NCT06938867·Phase 1, Phase 2·Recruiting

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Prevail Global Study

for Coronary Artery Disease

51 locations incl. Birmingham

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT06535854·Recruiting

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Sleep Restriction and Parental History of Hypertension

for Hypertension

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT06482814·Recruiting

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Treatment of Upper Gastrointestinal Symptoms Using Hypnotherapy Sessions

for GI Symptoms

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06846359·Recruiting

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A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus

for Congenital Cytomegalovirus Infection

10 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 0 Days - 90 Days

Code: NCT06118515·Phase 1·Recruiting

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Sensing Physiological Symptoms of Opioid Withdrawal and Cravings in Patients With Opioid Use Disorder

for Opioid Withdrawal

2 locations incl. Center City

Sponsor: Spark Biomedical, Inc.

Sex: All·Age: 18 - 50

Code: NCT06487533·Recruiting

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An Open-Label, Pilot Clinical Trial To Test The Safety And Feasibility Of A Suspension of Freeze-dried Microbiota In Patients Undergoing Colon Resection

for Recurrent Clostridioides Difficile Infection

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06692179·Phase 1·Recruiting

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A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

for Sickle Cell Disease

Drug: Etavopivat

50 locations incl. Birmingham

Sponsor: Novo Nordisk A/S

Sex: All·Age: 12+

Code: NCT06612268·Phase 3·Recruiting

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The PeriCut Catheter System Early Feasibility Study (REIMAGINE-HFpEF)

for Heart Failure With Preserved Ejection Fraction

1 location in Rochester

Sponsor: Heart Failure Solutions, Inc.

Sex: All·Age: 30+

Code: NCT06702501·Recruiting

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Cryoprobe Biopsy and Chronic Rejection in Lung Transplant Recipients

for Lung Transplant Rejection

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 99

Code: NCT06824402·Recruiting

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A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma

for Primary Open Angle Glaucoma

24 locations incl. Glendale

Sponsor: AbbVie

Sex: All·Age: 45+

Code: NCT06822738·Phase 3·Recruiting

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A Study of Hemodynamic Cardiopulmonary Exercise for CHD

for Congenital Heart Disease

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06566196·Recruiting

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Intravenous Ketamine for Treatment-Resistant Depression

for Depressive Disorder, Treatment-Resistant

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 65

Code: NCT06668571·Phase 2·Recruiting

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Assessment of Risks of Perinephric Fat Thickness to Adverse Renal Outcomes Post Donor Nephrectomy

for Living Kidney Donation

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06886087·Recruiting

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Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

for Castration-Resistant Prostate Carcinoma

107 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06632977·Phase 2·Recruiting

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REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

for Aortic Stenosis

71 locations incl. Birmingham

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18 - 105

Code: NCT06777368·Recruiting

Apply to this trial