Sleep Restriction and Parental History of Hypertension

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT06482814
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 35 Years
Healthy Volunteers
Accepted

Interventions

  • Partial sleep deprivation (sleep restriction) — BEHAVIORAL
    During the experimental segment the sleep opportunity will be restricted to 5 hours/night. During the acclimation and recovery phases a 9-hour/night sleep opportunity will be provided.
  • Normal sleep — BEHAVIORAL
    During the normal sleep condition a 9-hour/night sleep opportunity will be provided throughout the 10-day inpatient visit.

Study Details

The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.

Key Dates

Start date
Feb 20, 2025
Status verified
Jul 2025
Primary completion
Apr 30, 2029
Completion
Apr 30, 2029

Study Design

Enrollment
44 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER

Arms

  • Experimental: Study Sequence AB
    Sleep restriction condition in the first period and normal sleep condition in the second period. Each period will consist of a 10-day inpatient visit comprising a 3-day/2-night baseline, followed by a 5-day/5-night experimental phase, and a 2-day/2-night recovery phase.
  • Experimental: Study Sequence BA
    Normal sleep condition in the first period and sleep restriction condition in the second period. Each period will consist of a 10-day inpatient visit comprising a 3-day/2-night baseline, followed by a 5-day/5-night experimental phase, and a 2-day/2-night recovery phase.

Primary Outcome Measure

24-hour Systolic Blood Pressure (BP) [ Time Frame: Day 2, Day 4, Day 7, and Day 9 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo Clinic in RochesterRochesterMinnesota55905
Naima Covassin (PRINCIPAL_INVESTIGATOR)

Find similar trials in Rochester, MN

By condition
Hypertension (high blood pressure)
By specialty
CardiologyHeart disease
By research site
Mayo Clinic in Rochester· Rochester, MN

Related Studies