Paid Clinical Trials in Minnesota

Minnesota has 2,364 paid clinical trials enrolling now across cities including Rochester, Minneapolis and Saint Paul. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Minnesota include Mayo Clinic and University of Minnesota Medical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,364 clinical trials

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Tumor-Derived Extracellular Vesicles for Noninvasive Molecular Classification of Kidney Cancer

for Renal Cell Carcinoma

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: All ages

Code: NCT07243067·Not Yet Recruiting

MRI and Local Anesthesia

for Dental Anesthesia

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07602686·Not Yet Recruiting

A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 Therapy

for Multiple Sclerosis

10 locations incl. Birmingham

Sponsor: Genentech, Inc.

Sex: All·Age: 18 - 65

Code: NCT07609719·Phase 4·Not Yet Recruiting

R01_Pilot Jaw Muscle Phenotypes

for Chronic TMD Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07153107·Not Yet Recruiting

Optimization of Adaptive Rowing Seating

for Spinal Cord Diseases

2 locations incl. Minneapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07099625·Not Yet Recruiting

Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations

for Epilepsy

2 locations incl. Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 3 - 70

Code: NCT06898138·Not Yet Recruiting

Varenicline for Smoking Reduction in Veterans Not Ready To Quit

for Veterans

4 locations incl. San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 21+

Code: NCT06966362·Phase 4·Not Yet Recruiting

Remote Assessment of Digital Neurologic Testing

for Neurology

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07014982·Not Yet Recruiting

Simultaneous Engagement of Networks for Alleviating Pain (SENAP)

for Neuropathic Pain

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 22+

Code: NCT07057206·Phase 1·Not Yet Recruiting

Vaped Phenanthrene

for Former Smoker

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07134426·Not Yet Recruiting

Influence Of A Slope Adaptive Foot On Participation Of Veterans With Lower-Limb Amputations

for Amputation

1 location in Minneapolis

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 89

Code: NCT07266077·Not Yet Recruiting

COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

for New Onset Refractory Status Epilepticus

Drug: Tocilizumab

25 locations incl. Phoenix

Sponsor: Yale University

Sex: All·Age: 2+

Code: NCT07281027·Phase 3·Not Yet Recruiting

How Does Vagus Nerve Stimulation Affect Blood Glucose, Food, and Movement Cravings?

for Vagus Nerve Stimulation

1 location in Duluth

Sponsor: University of Minnesota

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT07457372·Not Yet Recruiting

Validation and Feasibility of Noninvasive Oxygen Delivery Index Monitoring in Cardiac Surgery Patients

for Cardiac Surgery

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07573306·Not Yet Recruiting

The Healing and Empowerment Actions for Recovery From Trauma (HEART) Trial

for Trauma Blunt

7 locations incl. Aurora

Sponsor: Stephanie Di Stasi

Sex: All·Age: 18+

Code: NCT07584252·Not Yet Recruiting

The Effect Of Lisinopril On Polycythemia

for Polycythemia

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80

Code: NCT07594535·Phase 4·Not Yet Recruiting

The Effect of the Safe and Sound Protocol on Depression and Anxiety Symptoms

for Anxiety

1 location in Saint Paul

Sponsor: HealthPartners Institute

Sex: All·Age: 18+

Code: NCT06701578·Not Yet Recruiting

A Study Investigating Coagadex in the Treatment AFXD Associated With AL Amyloidosis

for Acquired Factor X Deficiency

2 locations incl. Phoenix

Sponsor: Kedrion S.p.A.

Sex: All·Age: 18 - 70

Code: NCT06963216·Phase 3·Recruiting

Apply to this trial

An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

for REM Sleep Behavior Disorder

19 locations incl. Los Angeles

Sponsor: Yale University

Sex: All·Age: 50 - 80

Code: NCT06996652·Phase 2·Not Yet Recruiting

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

for Lymphoma, Non-Hodgkin

23 locations incl. Duarte

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07101328·Phase 1·Not Yet Recruiting

IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)

for Relapsed/Refractory Primary Central Nervous System Lymphoma

Drug: Rituximab

14 locations incl. Phoenix

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT07104032·Phase 3·Recruiting

Apply to this trial

Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

for Epilepsy

12 locations incl. Phoenix

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110454·Recruiting

Apply to this trial

A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy

for Dilated Cardiomyopathy (DCM)

3 locations incl. San Diego

Sponsor: Rocket Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07137338·Phase 1·Recruiting

Apply to this trial

Adaptation of the STAIR-NT for First Responders

for PTSD - Post Traumatic Stress Disorder

1 location in Forest Lake

Sponsor: Florida State University

Sex: All·Age: 18+

Code: NCT07212140·Not Yet Recruiting

Remapping Text in Sentence and Word Tasks to Aid Reading With Central Vision Loss

for Macular Degeneration

1 location in Edina

Sponsor: University of Minnesota

Sex: All·Age: 16+

Code: NCT07216924·Not Yet Recruiting

Reducing Risk of Diabetic Ketoacidosis in Type 1 Diabetes and Kidney Disease Using Continuous Ketone Monitoring

for Type 1 Diabetes Mellitus

1 location in Minneapolis

Sponsor: HealthPartners Institute

Sex: All·Age: 18 - 75

Code: NCT07325201·Phase 2·Not Yet Recruiting

EMS-Initiated Buprenorphine

for Opioid Use Disorder

3 locations incl. Oakland

Sponsor: Yale University

Sex: All·Age: All ages

Code: NCT07475728·Not Yet Recruiting

Fainting Detection And Early Warning In Syncope Evaluation Study (ARISE)

for Orthostatic Hypotension

1 location in Rochester

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07502599·Not Yet Recruiting

Dose Schedule Study of BCMA Bispecific Antibody, Elranatamab, for Newly Diagnosed Immunoglobulin Light Chain (AL) Amyloidosis

for Amyloid Light-chain Amyloidosis

Drug: Elranatamab

2 locations incl. Rochester

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07524634·Phase 2·Not Yet Recruiting

Evaluate the Effect of Vimseltinib on Pharmacokinetics of Combined Oral Contraceptive (Ethinyl Estradiol/Levonorgestrel)

for Healthy Participants

1 location in Saint Paul

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: Female·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07539090·Phase 1·Recruiting

Apply to this trial

A Study Of Stellate Ganglion Blockade With Liposomal Bupivacaine In Preventing Atrial Fibrillation After Isolated Coronary Artery Bypass Grafting Surgery

for Coronary Artery Disease

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 40+

Code: NCT07570940·Phase 4·Not Yet Recruiting

A Study Of Acute Decompensated Heart Failure

for Acute Decompensated Heart Failure

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07572955·Not Yet Recruiting

An International Multicenter, Multivendor Evaluation of the Free-Running Framework for Cardiac Function

for Congenital Heart Diseases

9 locations incl. Los Angeles

Sponsor: Matthias Stuber

Sex: All·Age: All ages

Code: NCT07613398·Not Yet Recruiting

AUR103 Calcium in Advanced Neuroendocrine Tumours (BHARAT-3 Study)

for Neuroendocrine (NE) Tumors

5 locations incl. Phoenix

Sponsor: Aurigene Discovery Technologies Limited

Sex: All·Age: 18 - 99

Code: NCT07640737·Phase 2·Not Yet Recruiting

A Study Of Focused Shockwave For Anterior Knee Pain Following Anterior Cruciate Ligament Reconstruction

for Anterior Cruciate Ligament Injuries

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07580157·Enrolling By Invitation

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

for Systemic Sclerosis

Drug: Nerandomilast

30 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07497087·Phase 3·Not Yet Recruiting

Itraconazole Therapy In Bronchiectasis With Airway Mold

for Bronchiectasis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07283497·Phase 4·Recruiting

Apply to this trial

B-PaLMZ for TB Meningitis

for Tuberculous Meningitis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07227779·Phase 2·Not Yet Recruiting

PASCAL Feasibility Study

for Smoking Cessation

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT07301151·Not Yet Recruiting

DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for Extrapulmonary Neuroendocrine Cancer

Drug: Obrixtamig

21 locations incl. Scottsdale

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07544654·Phase 3·Not Yet Recruiting