Remapping Text in Sentence and Word Tasks to Aid Reading With Central Vision Loss

Part of paid clinical trials in Edina, Minnesota.

Sponsor
University of Minnesota
Study ID
NCT07216924
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
16 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Personalised Remapping Training — BEHAVIORAL
    Participants will receive training across multiple days with text being shifted in real time as it is being read from locations covered by scotoma to locations determined by personalization procedure .
  • RSVP personalized remappi — BEHAVIORAL
    Participants will read one word at a time presented in rapid succession at fixation with text being shifted from scotoma locations to locations determined by personalization procedure.
  • Reading text in the wild with remapping — BEHAVIORAL
    Participants will read short texts presented in natural scenes in virtual reality with text being shifted from scotoma locations to locations determined by personalization procedure.

Study Details

Reading performance in patients with Central Vision Loss will be measured with and without missing text being remapped to different parts of the visual field in a variety of different reading tasks.

Key Dates

Start date
Jun 30, 2026
Status verified
Oct 2025
Primary completion
May 31, 2031
Completion
May 31, 2032

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Perceptual Learning
    Participants will practice reading with remapping over many sessions on different days.
  • Experimental: Rapid Serial Visual Presentation
    Participants will read words presented one at a time in rapid succession near fixation.
  • Experimental: Reading in The Wild
    Participants will view scenes in virtual reality showing natural settings and read a single word at a time within those scenes- e.g. a name on a street sign or shop in a city scene.

Primary Outcome Measure

Sentence reading speed [ Time Frame: Measured on day 35, end of the Personalised Remapping Training in the 33 participants in the Perceptual Learning arm. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MinnesotaEdinaMinnesota55416
Stephen A Engel, Ph.D.
[email protected]
9522852895
[email protected]
Stephen Engel, Ph.D. (PRINCIPAL_INVESTIGATOR)

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