Clinical Trials at University of Minnesota

As of June 2026, 327 paid clinical trials are recruiting at University of Minnesota, located at University of Minnesota Clinical Research Unit (CRU), 516 Delaware St SE, Minneapolis, MN 55455 in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

327 clinical trials at University of Minnesota

·Clear filters·↓ Download CSV

AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)

for Phenylketonurias

5 locations incl. Orange

Sponsor: NGGT INC.

Sex: All·Age: 18 - 55

Code: NCT06332807·Phase 1, Phase 2·Recruiting

Apply to this trial

Cryo Rib Fracture Study

for Rib Fractures

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06347874·Phase 4·Recruiting

Apply to this trial

Corticosteroid Injection Versus Nerve Block

for Glenohumeral Arthritis

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 99

Code: NCT06735027·Recruiting

Apply to this trial

Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

for Oral Leukoplakia

2 locations incl. Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT05727761·Phase 2·Recruiting

Apply to this trial

Clinical Data Collection for Obstetric Ultrasound Algorithms

for Pregnancy

2 locations incl. Minneapolis

Sponsor: Caption Health, Inc.

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06742229·Not Yet Recruiting

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

Drug: Amivantamab

150 locations incl. Daphne

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06667076·Phase 2·Recruiting

Apply to this trial

Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure

for Hypertension

Drug: Empagliflozin

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 60+

Code: NCT06507657·EARLY_Phase 1·Recruiting

Apply to this trial

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.

for Candidemia

23 locations incl. Birmingham

Sponsor: Basilea Pharmaceutica

Sex: All·Age: 18+

Code: NCT05421858·Phase 3·Recruiting

Apply to this trial

Support for Transgender and Non-Binary Individuals Seeking Vaginoplasty Study

for Gender Affirmation Surgery

9 locations incl. San Francisco

Sponsor: Oregon Health and Science University

Sex: Male·Age: 18+

Code: NCT06436560·Enrolling By Invitation

BeCoMe-9: A Clinical Study of BE-101 for the Treatment of Adults With Moderately Severe or Severe Hemophilia B

for Hemophilia B

4 locations incl. Davis

Sponsor: Be Biopharma

Sex: Male·Age: 18+

Code: NCT06611436·Phase 1, Phase 2·Recruiting

Apply to this trial

Tuberoplasty Versus Balloon Spacer

for Rotator Cuff Tears

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 65+

Code: NCT06735170·Phase 1, Phase 2·Recruiting

Apply to this trial

Characterizing the Pathophysiological Role of the Pallido-thalamocortical Motor Pathway in Parkinson's Disease.

for Parkinson Disease

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 75

Code: NCT06692920·Recruiting

Apply to this trial

Cognitive Function in Rett Syndrome During Trofinetide Treatment

for Rett Syndrome

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 99

Code: NCT06705816·Recruiting

Apply to this trial

Optimizing Transcranial Magnetic Stimulation for Stimulant Use Disorder

for Stimulant Use Disorder

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06790576·Phase 1·Recruiting

Apply to this trial

Phase 1 Study of GC1130A in Patients With Sanfilippo Syndrome Type A (MPS IIIA)

for Sanfilippo Syndrome Type A

2 locations incl. Oakland

Sponsor: GC Biopharma Corp

Sex: All·Age: 12 Months - 18

Code: NCT06567769·Phase 1·Recruiting

Apply to this trial

CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

for Epithelial Ovarian Cancer

26 locations incl. Phoenix

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18+

Code: NCT06690775·Phase 2·Recruiting

Apply to this trial

Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

6 locations incl. Los Angeles

Sponsor: Syntrix Biosystems, Inc.

Sex: Male·Age: 18+

Code: NCT06228053·Phase 2·Recruiting

Apply to this trial

Development of a Novel Evaluation Scale of Mental Body Representation (MBR) for Adults With Spinal Cord Injury

for Spinal Cord Injuries

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07029802·Recruiting

Apply to this trial

Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study

for Chronic Subdural Hematoma

31 locations incl. Phoenix

Sponsor: The University of Texas Medical Branch, Galveston

Sex: All·Age: 40 - 90

Code: NCT06347796·Recruiting

Apply to this trial

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

for Scleroderma, Diffuse

14 locations incl. Los Angeles

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 70

Code: NCT06655896·Phase 2·Recruiting

Apply to this trial

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

for Cardiovascular Diseases

37 locations incl. Little Rock

Sponsor: BrioHealth Solutions, Inc.

Sex: All·Age: 18 - 100

Code: NCT06310031·Recruiting

Apply to this trial

A Placebo-controlled, Randomized Clinical Trial to Assess the Safety, Feasibility, and Pharmacokinetics of Microbiota Transplant Therapy With Antibiotic Preconditioning and Fiber Supplementation in Patients With Pulmonary Arterial Hypertension

for Pulmonary Arterial Hypertension

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 75

Code: NCT06481852·Phase 1·Recruiting

Apply to this trial

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

for Long COVID

Drug: Baricitinib

17 locations incl. Tucson

Sponsor: Wes Ely

Sex: All·Age: 18+

Code: NCT06631287·Phase 3·Recruiting

Apply to this trial

A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia

for Primary Immune Thrombocytopenia (ITP)

18 locations incl. Phoenix

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06544499·Phase 3·Recruiting

Apply to this trial

Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06401577·Recruiting

Apply to this trial

Brain Vascular and Neural Function Linked to Balance Across the Adult Lifespan

for Neurotypical

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21 - 95·Accepts healthy volunteers

Code: NCT06127667·Recruiting

Apply to this trial

Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture

for Hip Fractures

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 85

Code: NCT06278987·Phase 4·Recruiting

Apply to this trial

CompuFlo CathCheck

for Epidural Placement

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 99

Code: NCT06460155·Phase 4·Recruiting

Apply to this trial

Bionic Pancreas in CFRD

for Cystic Fibrosis-related Diabetes

16 locations incl. Aurora

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 14+

Code: NCT06449677·Phase 3·Recruiting

Apply to this trial

Endogenous Pain Inhibition Deficiency in Chronic TMD Pain

for Chronic Temporomandibular Disorders (TMD)

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 74·Accepts healthy volunteers

Code: NCT06617494·Recruiting

Apply to this trial

Multicenter ALS Imaging Study

for Amyotrophic Lateral Sclerosis

3 locations incl. Gainesville

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06735014·Recruiting

Apply to this trial

Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

for Lung Transplant

18 locations incl. Los Angeles

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06399302·Recruiting

Apply to this trial

LMN-201 for Prevention of C. Difficile Infection Recurrence

for Clostridioides Difficile Infection

16 locations incl. Escondido

Sponsor: Lumen Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT05330182·Phase 2, Phase 3·Recruiting

Apply to this trial

HAPPINESS: cHAnging the Perceived Pain INtEnSity in Populations With Spinal Cord Injury and With Health Disparities: A Feasibility Study

for Spinal Cord Injuries

3 locations incl. Miami

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06140355·Recruiting

Apply to this trial

Addition of a Pectoserratus Block to Interscalene Block in Patients Undergoing Total Shoulder Replacement

for Total Shoulder Arthroplasty

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 85

Code: NCT06143306·Phase 4·Recruiting

Apply to this trial

Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults (The Exergames Telerehabilitation Study)

for At Risk for AD-dementia, With Subjective Cognitive Decline

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 65 - 99·Accepts healthy volunteers

Code: NCT06340659·Recruiting

Apply to this trial

tDCS and Cognitive Training for Restrictive Eating Disorders

for Anorexia Nervosa

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 65

Code: NCT06624150·Phase 1·Recruiting

Apply to this trial

Ostomy Simulation for Patient Education Prior to Urologic Bowel Diversion Surgeries

for Ostomy

1 location in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT06583577·Recruiting

Apply to this trial

ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting

Apply to this trial

PREVENT ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06581861·Recruiting

Apply to this trial