Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

Part of paid clinical trials in Los Angeles, California.

Sponsor
Syntrix Biosystems, Inc.
Study ID
NCT06228053
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
MALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • SX-682 — DRUG
    Specified dose twice daily
  • Enzalutamide — DRUG
    Specified dose once daily

Study Details

The goal of this clinical trial is to study the combination of SX-682 plus enzalutamide in men with metastatic castration resistant prostate cancer (mCRPC) who have failed prior therapy with androgen receptor pathway inhibitors.

Key Dates

Start date
Nov 18, 2024
Status verified
May 2026
Primary completion
Jun 30, 2027
Completion
Jun 30, 2028

Study Design

Enrollment
53 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: SX-682 + enzalutamide

Primary Outcome Measure

Clinical Benefit [ Time Frame: Ten 21-day treatment cycles ]

Central Contacts

Locations (6)

FacilityCityStateZIPSite coordinators
University of California, Los AngelesLos AngelesCalifornia90095
Rosa Lara Vazquez
[email protected]
Adam E. Singer, MD, PhD (PRINCIPAL_INVESTIGATOR)
University of California, San FranciscoSan FranciscoCalifornia94143
Danny Avins
[email protected]
Kelly Fitzgerald, MD (PRINCIPAL_INVESTIGATOR)
University of MichiganAnn ArborMichigan48109
Syntrix Biosystems Clinical Trials
[email protected]
Zachery R. Reichert, MD, PhD (PRINCIPAL_INVESTIGATOR)
University of MinnesotaMinneapolisMinnesota55455
Syntrix Biosystems Clinical Trials
[email protected]
Duke UniversityDurhamNorth Carolina27710
Julia Hurrelbrink
[email protected]
Andrew J. Armstrong, MD, ScM, FACP (PRINCIPAL_INVESTIGATOR)
University of WisconsinMadisonWisconsin53792
UW Carbone Cancer Center - Cancer Connect
[email protected]
800-622-8922
Douglas G. McNeel, MD, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Los Angeles, CA

By condition
Prostate cancer
By specialty
OncologyProstate oncologyMen's healthUrology
By research site
University of California, Los Angeles· Los Angeles, CAUniversity of California, San Francisco· San Francisco, CAUniversity of Michigan· Ann Arbor, MIUniversity of Minnesota· Minneapolis, MNDuke University· Durham, NCUniversity of Wisconsin· Madison, WI

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