A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitisfor Antineutrophil Cytoplasmic Antibody-associated VasculitisDrug: Avacopan60 locations incl. AnchorageSponsor: AmgenSex: All·Age: 18 - 100Code: NCT06072482·Phase 4·RecruitingApply to this trial
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Studyfor Muscle Invasive Bladder Urothelial Carcinoma490 locations incl. PhoenixSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT05987241·Phase 2, Phase 3·RecruitingApply to this trial
Promoting CT Engagement for Pancreatic Cancer With Appfor Pancreas Cancer2 locations incl. Chapel HillSponsor: UNC Lineberger Comprehensive Cancer CenterSex: All·Age: 18+Code: NCT06252545·RecruitingApply to this trial
A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomidefor Multiple MyelomaDrug: Talquetamab49 locations incl. ClovisSponsor: Janssen Research & Development, LLCSex: All·Age: 18+Code: NCT06208150·Phase 3·RecruitingApply to this trial
Blood Flow Regulation and Neuromuscular Function Post-Strokefor Stroke2 locations incl. MilwaukeeSponsor: Medical College of WisconsinSex: All·Age: 18 - 85Code: NCT06027294·RecruitingApply to this trial
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)for Prostate Cancer Metastatic44 locations incl. OrangeSponsor: Merck Sharp & Dohme LLCSex: All·Age: All agesCode: NCT06136624·Phase 3·RecruitingApply to this trial
Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinomafor Cholangiocarcinoma19 locations incl. Santa MonicaSponsor: TransThera Sciences (Nanjing), Inc.Sex: All·Age: 18+Code: NCT05948475·Phase 3·RecruitingApply to this trial
Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancerfor Recurrent Endometrial Carcinoma14 locations incl. AugustaSponsor: National Cancer Institute (NCI)Sex: Female·Age: 18+Code: NCT05950464·Phase 1·RecruitingApply to this trial
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)for Metastatic Castration-resistant Prostate Cancer (mCRPC)62 locations incl. TucsonSponsor: Merck Sharp & Dohme LLCSex: All·Age: 18+Code: NCT06136650·Phase 3·RecruitingApply to this trial
BLOCK-SAH - PPF-Block for Post-SAH Headachefor Subarachnoid Hemorrhage, Aneurysmal11 locations incl. GainesvilleSponsor: University of FloridaSex: All·Age: 18 - 85Code: NCT06008795·Phase 2·RecruitingApply to this trial
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancerfor Prostate Adenocarcinoma388 locations incl. BirminghamSponsor: NRG OncologySex: Male·Age: 18+Code: NCT05946213·Phase 3·RecruitingApply to this trial
Sequential Therapy in Multiple Myeloma Guided by MRD Assessmentsfor Multiple Myeloma10 locations incl. BirminghamSponsor: University of Alabama at BirminghamSex: All·Age: 18+Code: NCT05231629·Phase 2·RecruitingApply to this trial
Evaluation of the GORE® Ascending Stent Graftfor Aortic Aneurysm, Thoracic41 locations incl. BirminghamSponsor: W.L.Gore & AssociatesSex: All·Age: 18+Code: NCT05800743·Enrolling By Invitation
Prehospital Analgesia INtervention Trial (PAIN)for Traumatic Injury11 locations incl. San DiegoSponsor: Jason SperrySex: All·Age: 18+Code: NCT05437575·Phase 3·RecruitingApply to this trial
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancerfor Anatomic Stage II Breast Cancer AJCC v8Drug: Durvalumab536 locations incl. BirminghamSponsor: National Cancer Institute (NCI)Sex: All·Age: 18+Code: NCT06058377·Phase 3·RecruitingApply to this trial
Transcranial Alternating Current Stimulation (tACS) for the Recovery of Phonological Short-Term Memory in Patients With Aphasia After Strokefor Stroke1 location in MilwaukeeSponsor: Medical College of WisconsinSex: All·Age: 18+Code: NCT06048159·RecruitingApply to this trial
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)for Progressive Pulmonary Fibrosis70 locations incl. BirminghamSponsor: United TherapeuticsSex: All·Age: 18+Code: NCT05943535·Phase 3·RecruitingApply to this trial
Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphomafor Mantle Cell Lymphoma237 locations incl. Little RockSponsor: Alliance for Clinical Trials in OncologySex: All·Age: 60+Code: NCT05976763·Phase 3·RecruitingApply to this trial
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25for Breast Cancer1208 locations incl. BirminghamSponsor: NRG OncologySex: Female·Age: 18 - 60Code: NCT05879926·Phase 3·RecruitingApply to this trial
AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumoniafor Community-acquired Pneumonia6 locations incl. ChicagoSponsor: University of ManitobaSex: All·Age: 18+Code: NCT05848713·Phase 3·RecruitingApply to this trial
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Studyfor Metastatic Colorectal Adenocarcinoma184 locations incl. KingmanSponsor: Alliance for Clinical Trials in OncologySex: All·Age: 18+Code: NCT05673148·Phase 3·RecruitingApply to this trial
Observational Study for Patients at Risk for Chronic Graft-Versus-Host Diseasefor cGVHD32 locations incl. BirminghamSponsor: Incyte CorporationSex: All·Age: 18+Code: NCT05919511·RecruitingApply to this trial
Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapyfor Pulmonary Embolism40 locations incl. BirminghamSponsor: NYU Langone HealthSex: All·Age: 18+Code: NCT05591118·Phase 3·RecruitingApply to this trial
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancerfor Locally Advanced Lung Non-Small Cell Carcinoma470 locations incl. BirminghamSponsor: NRG OncologySex: All·Age: 18+Code: NCT05624996·Phase 3·RecruitingApply to this trial
Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patientsfor Obesity, Morbid4 locations incl. ChicagoSponsor: Rush University Medical CenterSex: All·Age: 18+Code: NCT05918575·RecruitingApply to this trial
Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapyfor Lymphoid Leukemia22 locations incl. TucsonSponsor: Stanford UniversitySex: All·Age: Up to 26Code: NCT05865301·RecruitingApply to this trial
A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatmentfor Glioblastoma Multiforme5 locations incl. Los AngelesSponsor: Cedars-Sinai Medical CenterSex: All·Age: 18+Code: NCT05708352·Phase 2·RecruitingApply to this trial
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants With Hearing Loss Due to Otoferlin Mutationsfor Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)9 locations incl. Los AngelesSponsor: Regeneron PharmaceuticalsSex: All·Age: Up to 17Code: NCT05788536·Phase 1, Phase 2·RecruitingApply to this trial
Epcoritamab and Rituximab for First-line Follicular Lymphomafor Follicular LymphomaDrug: Epcoritamab6 locations incl. BostonSponsor: Reid Merryman, MDSex: All·Age: 18+Code: NCT05783609·Phase 2·RecruitingApply to this trial
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumabfor Anatomic Stage II Breast Cancer AJCC v8820 locations incl. BirminghamSponsor: Alliance for Clinical Trials in OncologySex: All·Age: 18+Code: NCT05812807·Phase 3·RecruitingApply to this trial
Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphomafor Diffuse Large B-Cell Lymphoma87 locations incl. TucsonSponsor: SWOG Cancer Research NetworkSex: All·Age: 18+Code: NCT05633615·Phase 2·RecruitingApply to this trial
Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Diseasefor Crohn Disease22 locations incl. PhoenixSponsor: Connecticut Children's Medical CenterSex: All·Age: 6 - 17Code: NCT05781152·Phase 4·RecruitingApply to this trial
Targeted Immunotherapy After Myeloablative TBI-Based Conditioning & AlloHCT in CAYA With High Risk T-Cell ALL & Lymphomafor T-cell Acute Lymphoblastic Leukemia16 locations incl. PhoenizSponsor: New York Medical CollegeSex: All·Age: Up to 39Code: NCT04972942·Phase 1·RecruitingApply to this trial
XTX301 in Patients With Advanced Solid Tumorsfor Advanced Solid Tumor11 locations incl. SacramentoSponsor: Xilio Development, Inc.Sex: All·Age: 18+Code: NCT05684965·Phase 1, Phase 2·RecruitingApply to this trial
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphomafor Relapsed Non-Hodgkin Lymphoma32 locations incl. IrvineSponsor: Lyell Immunopharma, Inc.Sex: All·Age: 18+Code: NCT05826535·Phase 1, Phase 2·RecruitingApply to this trial
Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)for Recurrent Lung Non-Small Cell Carcinoma454 locations incl. DaphneSponsor: SWOG Cancer Research NetworkSex: All·Age: 18+Code: NCT05642572·Phase 2·RecruitingApply to this trial
A Study to Measure the Effect of Brain Stimulation on Hand Strength and Function in Patients With Brain Tumorsfor Brain Tumor1 location in MilwaukeeSponsor: Medical College of WisconsinSex: All·Age: 18 - 75·Accepts healthy volunteersCode: NCT05023434·RecruitingApply to this trial
Study of SGR-1505 in Mature B-Cell Neoplasmsfor Mature B-Cell Neoplasm16 locations incl. GilbertSponsor: Schrödinger, Inc.Sex: All·Age: 18+Code: NCT05544019·Phase 1·RecruitingApply to this trial
Pancreatic Cancer Detection Consortiumfor Pancreatic Cancer9 locations incl. PhoenixSponsor: City of Hope Medical CenterSex: All·Age: 18+·Accepts healthy volunteersCode: NCT06388967·RecruitingApply to this trial
TArgeting Type 1 Diabetes Using POLyamines (TADPOL)for Type 1 Diabetes7 locations incl. AuroraSponsor: Emily K. SimsSex: All·Age: 4 - 40Code: NCT05594563·Phase 2·RecruitingApply to this trial