Transcranial Alternating Current Stimulation (tACS) for the Recovery of Phonological Short-Term Memory in Patients With Aphasia After Stroke

Part of paid clinical trials in Milwaukee, Wisconsin.

Sponsor
Medical College of Wisconsin
Study ID
NCT06048159
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • HD-tACS — DEVICE
    High definition tACS will be applied during speech therapy.
  • Sham HD-tACS — DEVICE
    Sham high definition tACS will be applied during speech therapy.

Study Details

This study will assess the effects of transcranial alternating current stimulation (tACS) on language recovery after stroke.

Key Dates

Start date
Nov 6, 2023
Status verified
May 2025
Primary completion
Jan 31, 2033
Completion
Jan 31, 2033

Study Design

Enrollment
120 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: High Definition tACS with Short-term Memory Focused Speech Therapy
    High-Definition-tACS will be delivered via a battery operated alternating current stimulator (Soterix) using two 3x1 center-surround montages.The current is turned on and increased in a ramplike fashion over approximately 30 seconds. Participants will undergo tACS stimulation for 20-minutes with 2 milliampere (mA) peak-to-peak intensity. Stimulation will be maintained no longer than 20 minutes. This will be paired with short-term memory focused speech therapy.
  • Sham Comparator: Sham-High Definition tACS with Short-term Memory Focused Speech Therapy
    High-Definition-tACS will be delivered via a battery operated alternating current stimulator (Soterix) using two 3x1 center-surround montages. The current is turned on and increased in a ramplike fashion for 10 to 30 seconds and then ramped down. In this way, the participants experience the same initial sensations (mild tingling) as the active tACS groups. This will be paired with short-term memory focused speech therapy.

Primary Outcome Measure

Accuracy on a phonological STM task [ Time Frame: Upon the completion of therapy cycle (a cycle consists of 10 intervention days) and 10 weeks post ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Medical College of WisconsinMilwaukeeWisconsin53226
Sidney E Schoenrock, MA
[email protected]
414-955-7579
Priyanka Shah-Basak, PhD
[email protected]
414-955-5752

Find similar trials in Milwaukee, WI

By condition
Stroke
By specialty
NeurologyBrain disorders
By research site
Medical College of Wisconsin· Milwaukee, WI

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